Abstract
The clinical entity Wernicke’s disease was first described by Dr. Carl Wernicke in 1881. In this manuscript, Wernicke described both clinical features and autopsy findings (Wernicke, 1881). The description was of three patients, and clinical features consisted of ataxia, strabismus, nystagmus, diplopia, disorientation, and stupor. The findings at autopsy were similar and consisted of small hemorrhages located in periaqueductal gray. Wernicke interpreted this to be an acute inflammatory disease primarily of the ocular nuclei.
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© 2010 Humana Press, a part of Springer Science+Business Media, LLC
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McCandless, D.W. (2010). Wernicke’s Disease. In: Thiamine Deficiency and Associated Clinical Disorders. Contemporary Clinical Neuroscience. Humana Press. https://doi.org/10.1007/978-1-60761-311-4_5
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DOI: https://doi.org/10.1007/978-1-60761-311-4_5
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Online ISBN: 978-1-60761-311-4
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