Skip to main content
SpringerLink
Log in
Book cover

Primary Care Sleep Medicine pp 171–189Cite as

Sleep in Patients With Pulmonary Disease

  • Chapter

Part of the book series: Current Clinical Practice ((CCP))

Abstract

Sleep complaints are very prevalent in the patients with pulmonary disease. This review will examine sleep effects on respiration, explore ventilatory responses during sleep in normal individuals, and examine mechanisms of hypoxemia in patients with pulmonary disease. Sleep disorders in patients with obstructive pulmonary diseases, including chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), asthma, and restrictive parenchymal disease will be reviewed. A diagnostic evaluation and management plan are also suggested for these patients.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   89.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   119.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. McNicolas WT (1997) Impact of sleep in respiratory failure. Eur Respir J 10:920–933.

    Google Scholar 

  2. Phillipson EA (1978) Control of breathing during sleep. Am Rev Respir Dis 118:909–939.

    PubMed  CAS  Google Scholar 

  3. Douglas NJ (1985) Control of ventilation during sleep. Clin Chest Med 6:563–575.

    PubMed  CAS  Google Scholar 

  4. Krieger J (1985) Breathing during sleep in normal subjects. Clin Chest Med 6:577–594.

    PubMed  CAS  Google Scholar 

  5. Tabachnik E, Muller NL, Bryan AC, et al. (1981) Changes in ventilation and chest wall mechanics during sleep in normal adolescents. J Appl Physiol 51:557–564.

    PubMed  CAS  Google Scholar 

  6. Douglas NJ (1984) Control of breathing during sleep. Clin Sci 67:465–472.

    PubMed  CAS  Google Scholar 

  7. Hudgel DW, Hendricks C (1988) Palate and hypopharynx sites of inspiratory narrowing of the upper airway during sleep. Am Rev Respir Dis 138:1542–1547.

    PubMed  CAS  Google Scholar 

  8. Yap JC, Watson RA, Gilbey S, et al. (1995) Effects of posture on respiratory mechanics in obesity. J Appl Physiol 79:1199–1205.

    PubMed  CAS  Google Scholar 

  9. Lopes JM, Tabachnik E, Muller NL, et al. (1983) Total airway resistance and respiratory muscle activity during sleep. J Appl Physiol 54:773–777.

    PubMed  CAS  Google Scholar 

  10. Douglas NJ, White DP, Weil JV, et al. (1982) Hypoxic ventilatory response decreases during sleep in normal men. Am Rev Respir Dis 125:286–289.

    PubMed  CAS  Google Scholar 

  11. Douglas NJ, White DP, Weil JV, et al. (1982) Hypercapnic ventilatory response in sleeping adults. Am Rev Respir Dis 126:758–762.

    PubMed  CAS  Google Scholar 

  12. Hedemark LL, Kronenberg RS(1982) Ventilatory and heart rate responses to hypoxemia and hypercapnia during sleep in adults. J Appl Physiol 53:307–312.

    PubMed  CAS  Google Scholar 

  13. Issa FG, Sullivan CE (1983) Arousal and breathing responses to airway occlusion in healthy sleeping adults. J Appl Physiol 55:1113–1119.

    PubMed  CAS  Google Scholar 

  14. Mohsenin V (2005) Sleep in chronic obstructive pulmonary disease. Semin Respir Crit Care Med 26:109–116.

    Article  PubMed  Google Scholar 

  15. Celli BR, MacNee W (2004) American Thoracic Society/European Respiratory Society Task Force. Standards for the diagnosis and management of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J 23:932–946.

    PubMed  CAS  Google Scholar 

  16. Mannino DM, Homa DM, Akinbami LJ, et al. (2002) Chronic obstructive pulmonary disease surveillance: United States 1971-2000. MMWR 51:1–16.

    Google Scholar 

  17. O’Donoghue FJ, Catcheside PG, Ellis EE, et al. (2003) Sleep hypoventilation in hypercapnic chronic obstructive pulmonary disease: prevalence and associated factors. Eur Respir J 21:977–984.

    PubMed  CAS  Google Scholar 

  18. O’Donoghue FJ, Catcheside PG, Eckert DJ, et al. (2004) Changes in respiration in NREM sleep in hypercapnic chronic obstructive pulmonary disease. J Physiol 599:663–673.

    Article  CAS  Google Scholar 

  19. Weitzenblum E, Chaouat A(2004) Sleep and chronic obstructive pulmonary disease. Sleep Med Rev 8:281–294.

    Article  PubMed  Google Scholar 

  20. Aoki T, Ebihara A, Yogo Y, et al. (2005) Sleep-disordered breathing in patients with chronic obstructive pulmonary disease. COPD: J Chronic Obstructive Pulmonary Dis 2:243–252.

    Article  Google Scholar 

  21. Demarco FJ Jr, Wynne JS, Block AJ, et al. (1981) Oxygen desaturation during sleep as a determinant of the “blue and bloated” syndrome. Chest 79:621–625.

    PubMed  Google Scholar 

  22. Sanders MH, Newman AB, Haggerty CL, et al. (2003) Sleep Heart Health Study: sleep and sleepdisordered breathing in adults with predominantly mild obstructive airway disease. Am J Respir Crit Care Med 67:7–14.

    Article  Google Scholar 

  23. Bellia V, Catalano F, Scichilone N, et al. (2003) Sleep disorders in the elderly with and without chronic airflow obstruction: the SARA study. Sleep 26:318–323.

    PubMed  Google Scholar 

  24. Fleetham J, West P, Mezon B, et al. (1982) Sleep, arousals, and oxygen desaturation in chronic obstructive pulmonary disease: the effect of oxygen therapy. Am J Respir Dis 126:429–433.

    CAS  Google Scholar 

  25. Saaresranta T, Irjala K, Aittokallio T, et al. (2005) Sleep quality daytime sleepiness and fasting insulin levels in women with chronic obstructive pulmonary disease. Respir Med 99:856–863.

    Article  PubMed  Google Scholar 

  26. Coccagna G, Lugaresi E (1978) Arterial blood gases and pulmonary and systemic arterial pressure during sleep in chronic obstructive pulmonary disease. Sleep 1:117–124.

    PubMed  CAS  Google Scholar 

  27. Chaouat A, Weitzenblum E, Kessler R, et al. (1997) Sleep-related O2 desaturation and daytime pulmonary haemodynamics in COPD patients with mild hypoxaemia. Eur Resp J 10:1730–1735.

    Article  CAS  Google Scholar 

  28. Chaouat A, Weitzenblum E, Krieger J, et al. (1995) Association of chronic obstructive pulmonary disease and sleep apnea syndrome. Am J Respir Crit Care Med 151:82–86.

    PubMed  CAS  Google Scholar 

  29. Bradley TD, Rutherford R, Grossman RF, et al. (1985) Role of daytime hypoxemia in the pathogenesis of right heart failure in the obstructive sleep apnea syndrome. Am Rev Respir Dis 131:835–839.

    PubMed  CAS  Google Scholar 

  30. Fletcher EC, Luckett RA, Goodnight-White S, et al. (1992) A double-blind trial of nocturnal supplemental oxygen for sleep desaturation in patients with chronic obstructive pulmonary disease and a daytime Pao2 above 60 mm Hg. Am Rev Respir Dis 145:1070–1076.

    PubMed  CAS  Google Scholar 

  31. Connaughton JJ, Catterall JR, Elton RA, et al. (1988) Do sleep studies contribute to the management of patients with severe chronic obstructive pulmonary disease? Am Rev Respir Dis 138:341–344.

    PubMed  CAS  Google Scholar 

  32. Douglas NJ, Flenley DC (1990) Breathing during sleep in patients with obstructive lung disease. Am Rev Respir Dis 141:1055–1570.

    PubMed  CAS  Google Scholar 

  33. George CF, Bayliff CD (2003) Management of insomnia in patients with chronic obstructive pulmonary disease. Drugs 63:379–387.

    Article  PubMed  Google Scholar 

  34. Dolly FR, Block AJ (1983) Medroxyprogesterone acetate and COPD: effect on breathing and oxygenation in sleeping and awake patients. Chest 84:394–398.

    PubMed  CAS  Google Scholar 

  35. Saaresvanta T, Aittokallio T, Utriainen K, et al. (2005) Medroxyprogesterone improves nocturnal breathing in postmenopausal women with chronic obstructive pulmonary disease. Respir Res 6:28.

    Article  CAS  Google Scholar 

  36. McNicholas WT, Calverley PM, Lee A, et al. (2004) Long-acting inhaled anticholinergic therapy improves sleeping oxygen saturation in COPD. Eur Respir J 23:825–831.

    PubMed  CAS  Google Scholar 

  37. Gay PC (2004) Chronic obstructive pulmonary disease. Sleep Respir Care 49:39–51.

    Google Scholar 

  38. Hill NS (2004) Noninvasive ventilation for chronic obstructive pulmonary disease. Respir Care 49:72–87.

    PubMed  Google Scholar 

  39. Wijkstra PJ, Avendano MA, Goldstein RS (2003) Inpatient chronic assisted ventilatory care: a 15-year experience. Chest 124:850–856.

    Article  PubMed  Google Scholar 

  40. Clinical indications for noninvasive positive pressure ventilation in chronic respiratory failure due to restrictive lung disease, COPD, and nocturnal hypo ventilation: a consensus conference report. (1999) Chest 116:521–534.

    Article  Google Scholar 

  41. http://www.cms.hhs.gov/manuals/pm_trans/R1744233.pdf. Accessed Oct. 2006.

  42. Ramsey BW (1996) Management of pulmonary disease in patients with cystic fibrosis. N Engl J Med 335:179–180.

    Article  PubMed  CAS  Google Scholar 

  43. Jankelowitz L, Reid KJ, Wolfe L, et al. (2005) Cystic fibrosis patients have poor sleep quality despite normal sleep latency and efficiency. Chest 127:1593–1599.

    Article  PubMed  Google Scholar 

  44. Milross MA, Piper AJ, Dobbin CJ, et al. (2004) Sleep-disordered breathing in cystic fibrosis. Sleep Med Rev 8:295–308.

    Article  PubMed  Google Scholar 

  45. Milross MA, Piper AJ, Norman M, et al. (2001) Low-flow oxygenated bilevel ventilatory support: effects on ventilation during sleep in cystic fibrosis. Am J Respir Crit Care Med 163:129–134.

    PubMed  CAS  Google Scholar 

  46. Milross MA, Piper AJ, Norman M, et al. (2001) Predicting sleep-disordered breathing in patients with cystic fibrosis. Chest 120:1239–1248.

    Article  PubMed  CAS  Google Scholar 

  47. Frangolias MA, Wilcox PG (2001) Predictability of oxygen desaturation during sleep in patients with cystic fibrosis: clinical, spirometric, and exercise parameters. Chest 119:434–441.

    Article  PubMed  CAS  Google Scholar 

  48. Martin RJ (1992) Nocturnal asthma. Clin Chest Med 13:533–550.

    PubMed  CAS  Google Scholar 

  49. Turner-Warwick M (1988) Epidemiology of nocturnal asthma. Am J Med 85(Suppl 118):6–8.

    Article  PubMed  CAS  Google Scholar 

  50. Calhoun WJ (2003) Nocturnal asthma. Chest 123:399S–405S.

    Article  PubMed  Google Scholar 

  51. Turner-Warwick M (1977) On observing patterns of airflow obstruction in chronic asthma. Br J Dis Chest 71:73–86.

    Article  PubMed  CAS  Google Scholar 

  52. Douglas NJ (1985) Asthma at night. Clin Chest Med 6:663–674.

    PubMed  CAS  Google Scholar 

  53. Ryan G, Latimer KM, Dolovich J, et al. (1982) Bronchial responsiveness to histamine: relationship to diurnal variation of peak flow rate, improvement after bronchodilator, and airway caliber. Thorax 37:423–429.

    PubMed  CAS  Google Scholar 

  54. Martin RJ, Cicutto LC, Ballard RD (1990) Factors related to the nocturnal worsening of asthma. Am Rev Respir Dis 141:33–38.

    PubMed  CAS  Google Scholar 

  55. Sutherland ER, Martin RJ, Bowler RP, et al. (2004) Physiologic correlates of distal lung inflammation in asthma. J Allergy Clin Immunol 113:1046–1050.

    Article  PubMed  Google Scholar 

  56. Kraft M, Djukanovic R, Wilson S, et al. (1996) Alveolar tissue inflammation in asthma. Am J Respir Crit Care Med 154:1505–1509.

    PubMed  CAS  Google Scholar 

  57. Kraft M, Martin RJ, Wilson S, et al. (1999) Lymphocyte and eosinophil influx into alveolar tissue in nocturnal asthma. Am J Respir Crit Care Med 129:228–234.

    Google Scholar 

  58. Kraft M, Pak J, Martin RJ (2001) Distal lung dysfunction at night in nocturnal asthma. Am J Respir Crit Care Med 163:1551–1556.

    PubMed  CAS  Google Scholar 

  59. Kraft M, Striz I, Georges G, et al. (1998) Expression of epithelial markers in nocturnal asthma. J Allergy Clin Immunol 102:376–381.

    Article  PubMed  CAS  Google Scholar 

  60. Platts-Mills TAE, Mitchell BB, Nock P, et al. (1982) Reduction of bronchial reactivity during prolonged allergen avoidance. Lancet 2:675–677.

    Article  PubMed  CAS  Google Scholar 

  61. Turki J, Pak J, Green SA, et al. (1995) Genetic polymorphisms of the beta 2-adrenergic receptor in nocturnal and non-nocturnal asthma: evidence that the Gly-16 correlates with the nocturnal phenotype. J Clin Invest 95:1635–1641.

    Article  PubMed  CAS  Google Scholar 

  62. Sutherland ER, Kraft M, Rex MD, et al. (2003) Hypothalamic pituitary-adrenal axis dysfunction during sleep in nocturnal asthma. Chest 123:405S.

    Article  PubMed  Google Scholar 

  63. Sutherland ER, Ellison MC, Kraft M, et al. (2003) Altered pituitary adrenal interaction in nocturnal asthma. J Allergy Clin Immunol 112:52–57.

    Article  PubMed  CAS  Google Scholar 

  64. Kraft M, Vianna E, Martin RJ, et al. (1999) Nocturnal asthma is associated with reduced glucocorticoid receptor binding affinity. J Allergy Clin Immunol 103:66–71.

    Article  PubMed  CAS  Google Scholar 

  65. Sutherland ER, Ellison MC, Kraft M, et al. (2003) Elevated serum melatonin is associated with the nocturnal worsening of asthma. J Allergy Clin Immunol 112:513–517.

    Article  PubMed  CAS  Google Scholar 

  66. Morrison JF, Pearson SB, Dean HG (1988) Parasympathetic nervous system in nocturnal asthma. BMJ 296:1427–1429.

    PubMed  CAS  Google Scholar 

  67. Mackay TW, Hulks G, Douglas NJ (1998) Non-adrenergic, non-cholinergic function in the human airway. Respir Med 92:461–466.

    Article  PubMed  CAS  Google Scholar 

  68. Chen WY, Chai H (1982) Airway cooling and nocturnal asthma. Chest 81:675–680.

    PubMed  CAS  Google Scholar 

  69. Catterall JR, Rhind GB, Stewart IC, et al. (1986) Effects of sleep deprivation on overnight bronchoconstriction in nocturnal asthma. Thorax 41:676–680.

    Article  PubMed  CAS  Google Scholar 

  70. Kales A, Beall GN, Bajor GF, et al. (1968) Sleep studies in asthmatic adults: relationship of attacks to sleep stage and time of night. J Allergy 41:164–173.

    Article  PubMed  CAS  Google Scholar 

  71. Ballard RD, Irvin CG, Martin RJ, et al. (1990) Influences of sleep on lung volume in asthmatic patients and normal subjects. J Appl Physiol 68:2034–2041.

    PubMed  CAS  Google Scholar 

  72. Irvin CG, Pak J, Martin RJ (2000) Nocturnal asthma. Airway-parenchyma uncoupling in nocturnal asthma. Am J Respir Crit Care Med 161:50–56.

    PubMed  CAS  Google Scholar 

  73. Fitzpatrick MF, Engleman H, Whyte KF, et al. (1991) Morbidity in nocturnal asthma: sleep quality and daytime cognitive performance. Thorax 46:569–657.

    PubMed  CAS  Google Scholar 

  74. Weersink EJ, van Zomren EH, Köeter GH, et al. (1997) Treatment of nocturnal airway obstruction improves daytime cognitive performance in asthmatics. Am J Respir Crit Care Med 156:1144–1150.

    PubMed  CAS  Google Scholar 

  75. Qureshi A, Ballard RD (2003) Obstructive sleep apnea. J Allergy Clin Immunol 112:613–651.

    Article  Google Scholar 

  76. Ciftci TV, Ciftci B, Guren SF, et al. (2005) Effect of nasal continuous positive airway pressure in uncontrolled nocturnal asthmatic treatment with obstructive sleep apnea studies. Respir Med 99:529–534.

    Article  PubMed  Google Scholar 

  77. Chan CS, Woolcock AJ, Sullivan CE (1988) Nocturnal asthma: role of snoring and obstructive sleep apnea. Am Rev Respir Dis 137:1502–1504.

    PubMed  CAS  Google Scholar 

  78. Martin RJ, Pak J (1991) Nasal CPAP in non-apneic nocturnal asthma. Chest 100:1024–1027.

    PubMed  CAS  Google Scholar 

  79. Harding SM (1999) Nocturnal asthma: role of nocturnal gastroesophageal reflux. Chronobiol Intl 16:641–662.

    CAS  Google Scholar 

  80. Harding SM (1999) Gastroesophageal reflux and asthma: insight into the association. J Allergy Clin Immunol 105:251–259.

    Article  Google Scholar 

  81. Davis RS, Larsen GL, Grunstein MM (1983) Respiratory response to intraesophageal acid infusion in asthmatic children during sleep. J Allergy Clin Immunol 72:393–399.

    Article  PubMed  CAS  Google Scholar 

  82. Martin ME, Grunstein MM, Larsen GL (1982) The relationship of gastroesophageal reflux to nocturnal wheezing in children with asthma. Ann Allergy 49:318–322.

    PubMed  CAS  Google Scholar 

  83. Cuttita G, Cibella F, Visconti A, et al. (2000) Spontaneous gastroesophageal reflux and airway patency during the night in adult asthmatics. Am J Respir Crit Care Med 161:177–181.

    Google Scholar 

  84. Harding SM, Richter JE, Guzzo MR, et al. (1996) Asthma and gastroesophageal reflux: acid suppressive therapy improves asthma outcome. Am J Med 100:395–405.

    Article  PubMed  CAS  Google Scholar 

  85. National Institutes of Health. National asthma education and prevention program expert panel report 2: guidelines for the diagnosis and management of asthma. 1997; publication No 97-4051A, 1–80. Available at:http://www.nhlbi.nih.gov/guidelines/asthma/asthgdln.pdf. Accessed Oct. 2006.

  86. Harding SM, Guzzo MR, Richter JE (2000) The prevalence of gastroesophageal reflux in asthma patients without reflux symptoms. Am J Respir Crit Care Med 162:34–39.

    PubMed  CAS  Google Scholar 

  87. Hakala K, Stenius-Aanius-Aarnislaee B, Sovigarvi A (2000) Effects of weight loss on peak flow variability, airways obstruction, and lung volumes in obese patients with asthma. Chest 118:1315–1321.

    Article  PubMed  CAS  Google Scholar 

  88. Fitzpatrick MF, Mackay T, Driver H, et al. (1990) Salmeterol in nocturnal asthma: a double-blind, placebo-controlled trial of a long-acting inhaled beta-2 agonist. BMJ 301:1365–1368.

    PubMed  CAS  Google Scholar 

  89. Lockey RF, DuBuske LM, Friedman B, et al. (1999) Nocturnal asthma: effect of salmeterol on quality of life and clinical outcomes. Chest 115:666–673.

    Article  PubMed  CAS  Google Scholar 

  90. Kraft M, Wenzel SE, Bettinger GM, et al. (1997) The effect of salmeterol on nocturnal symptoms, airway function, and inflammation in asthma. Chest111:1249–1254.

    PubMed  CAS  Google Scholar 

  91. Martin RJ, Kraft M, Beaucher WN, et al. (1999) A comparative study of extended release albuterol sulfate and long-acting inhaled salmeterol xinafoate in the treatment of nocturnal asthma. Ann Allergy Asthma Immunol 83:121–126.

    PubMed  CAS  Google Scholar 

  92. Bogin RM, Ballard RD (1992) Treatment of nocturnal asthma with pulse-release albuterol. Chest 102:362–366.

    PubMed  CAS  Google Scholar 

  93. Pincus PJ, Szefler SJ, Ackerson CM, et al. (1995) Chronotherapy of asthma with inhaled steroids: the effect of dosage timing on drug efficacy. J Allergy Clin Immunol 95:1172–1178.

    Article  PubMed  CAS  Google Scholar 

  94. Weersink EJ, Douma RR, Postma DS, et al. (1997) Flulticasone propionate, salmeterol xinafoate, and their combination in the treatment of nocturnal asthma. Am J Respir Crit Care Med 155: 1241–1246.

    PubMed  CAS  Google Scholar 

  95. Beam RW, Weiner DE, Martin RJ, et al. (1992) Timing of prednisone and alterations of airways inflammation in nocturnal asthma. Am Rev Respir Dis 146:1524–1530.

    PubMed  CAS  Google Scholar 

  96. Reiss TF, Chervinsky P, Dockhorn RJ, et al. (1998) Montelukast, a once-daily leukotriene receptor antagonist, in the treatment of chronic asthma: a multicenter, randomized, double-blind trial. Arch Intern Med 158:1213–1230.

    Article  PubMed  CAS  Google Scholar 

  97. Ilowite J, Webb R, Friedman B, et al. (2004) Addition of montelukast or salmeterol to fluticasone for protection against asthma attacks: a randomized, double-blind, multicenter study. Ann Allergy Asthma Immunol 92:641–648.

    Article  PubMed  CAS  Google Scholar 

  98. Bjermen L, Bisgaaard H, Bousquet J, et al. (2003) Montelukast and fluticasone compared with salmeterol and fluticasone in protecting against asthma exacerbation in adults: one year, double blind, randomized comparative trial. BMJ 327:871–897.

    Article  Google Scholar 

  99. Kraft M, Torvik JA, Trudeau JB, et al. (1996) Theophylline: potential anti-inflammatory effects in nocturnal asthma. J Allergy Clin Immunol 97:1242–1246.

    Article  PubMed  CAS  Google Scholar 

  100. Selby C, Engleman HM, Fitzpatrick MF, et al. (1997) Inhaled salmeterol or oral theophylline in nocturnal asthma? Am J Respir Crit Care Med 155:104–108.

    PubMed  CAS  Google Scholar 

  101. Westby M, Benson M, Gibson P (2004) Anticholinergic agents for chronic asthma in adults. Cochrane Database Syst Rev 3:CD.

    Google Scholar 

  102. Skloot GS (2002) Nocturnal asthma: mechanisms and management. Mt Sinai J Med 69:140–147.

    PubMed  Google Scholar 

  103. McNicholas WT, Coffey M, Fitzgerald MX (1986) Ventilation and gas exchange during sleep in patients with interstitial lung disease. Thorax 41:777–782.

    PubMed  CAS  Google Scholar 

  104. Perez-Padilla R, West P, Lertzman M, et al. (1985) Breathing during sleep in patients with interstitial lung disease Am Rev Respir Dis 132:224–229.

    PubMed  CAS  Google Scholar 

  105. Clark M, Cooper B, Singh S, et al. (2001) A survey of nocturnal hypoxaemia and health-related quality of life in patients with cryptogenic fibrosing alveolitis. Thorax 56:482–486.

    Article  PubMed  CAS  Google Scholar 

  106. Turner GA, Lower EE, Corser BC, et al. (1997) Sleep apnea in sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis 14:61–64.

    PubMed  CAS  Google Scholar 

  107. Krachman SL, Criner CJ, Chatila W (2003) Cor pulmonale and sleep-disordered breathing in patients with restrictive lung disease and neuromuscular disease. Semin Respir Crit Care Med 24:297–306.

    Article  PubMed  Google Scholar 

  108. González MM, Parreira VF, Rodenstein DO (2002) Non-invasive ventilation and sleep. Sleep Med Revie 6:29–44.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, Medical Director, UAB Sleep/Wake Disorders Center, University of Alabama at Birmingham, Birmingham, AL

    Susan M. Harding MD, FCCP

Authors
  1. Susan M. Harding MD, FCCP
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Family Practice, University of Colorado School of Medicine, Southern Colorado Family Medicine Residency, Pueblo, CO

    James F. Pagel MS, MD

  2. Comprehensive Center for Sleep Medicine Department of Pulmonary, Critical Care, and Sleep Medicine, Mount Sinai School of Medicine, New York, NY

    S. R. Pandi-Perumal MSc

Rights and permissions

Reprints and permissions

Copyright information

© 2007 Humana Press Inc., Totowa, NJ

About this chapter

Cite this chapter

Harding, S.M. (2007). Sleep in Patients With Pulmonary Disease. In: Pagel, J.F., Pandi-Perumal, S.R. (eds) Primary Care Sleep Medicine. Current Clinical Practice. Humana Press. https://doi.org/10.1007/978-1-59745-421-6_16

Download citation

  • DOI: https://doi.org/10.1007/978-1-59745-421-6_16

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-992-5

  • Online ISBN: 978-1-59745-421-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation