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Platelet Signal-Dependent Protein Synthesis

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Platelet Function

Part of the book series: Contemporary Cardiology ((CONCARD))

Abstract

Our understanding of platelet functions has been in evolution since their discovery. Blood platelets were initially observed in the middle of the 19th century by many investigators including Zimmerman in 1860, Schultze in 1865, Osler in 1874, and Hayem in 1878 (1). Studies by Bizzozero (2,3) were the first to recognize the adhesive qualities of platelets, their participation in thrombosis and leukocyte recruitment, and their role in blood coagulation. These monumental findings, which have withstood the test of time, have expanded at a remarkable rate and continue to be the primary focus of investigative research in the platelet arena (4).

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Authors and Affiliations

  1. Department of Medicine, Johannes Gutenberg-University, Mainz, Germany

    Stephan Lindemann MD

  2. Departments of Internal Medicine and Pathology and the Eccles Institute of Human Genetics, University of Utah, Salt Lake City, UT

    Thomas M. McIntyre PhD

  3. Department of Internal Medicine and the Huntsman Cancer Institute, University of Utah, Salt Lake City, UT

    Stephen M. Prescott MD

  4. Department of Internal Medicine and the Eccles Institute of Human Genetics, University of Utah, Salt Lake City, UT

    Guy A. Zimmerman MD & Andrew S. Weyrich PhD

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  1. Stephan Lindemann MD
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  2. Thomas M. McIntyre PhD
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  3. Stephen M. Prescott MD
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  4. Guy A. Zimmerman MD
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  5. Andrew S. Weyrich PhD
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Editor information

Editors and Affiliations

  1. Department of Cardiology, St. Vincent’s University Hospital, Dublin, Ireland

    Martin Quinn MB BCh BAO, PhD

  2. University College Dublin, Dublin, Ireland

    Desmond Fitzgerald MD, FRCPI, FESC, AAP (Vice President of Research) (Vice President of Research)

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Lindemann, S., McIntyre, T.M., Prescott, S.M., Zimmerman, G.A., Weyrich, A.S. (2005). Platelet Signal-Dependent Protein Synthesis. In: Quinn, M., Fitzgerald, D. (eds) Platelet Function. Contemporary Cardiology. Humana Press. https://doi.org/10.1007/978-1-59259-917-2_6

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  • DOI: https://doi.org/10.1007/978-1-59259-917-2_6

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