Abstract
The variety of techniques that have been developed and applied to treat metastatic colon cancer to the liver is a testament to the importance of this clinical problem and to the failure of any single technique to have provided a solution in this clinical situation. Radiofrequency thermal ablation (RFA) is one of the most recent techniques to be applied to the treatment of primary and metastatic disease in the liver. It can be categorized together with cryosurgical ablation and direction injection of alcohol, chemotherapeutics, or gene therapy vectors as a treatment that targets a specific area or region of the liver. These treatment strategies can be characterized as “subregional” regional therapy as opposed to vascular-based treatment that treat the entire liver. RFA is the opposite of cryoablation, as it uses heat generated by electrical current to directly destroy tissue, as opposed to cold temperatures to accomplish the same goal (1).
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Fraker, D.L. (2002). Radiofrequency Ablation of Colorectal Metastases to the Liver. In: Saltz, L.B. (eds) Colorectal Cancer. Current Clinical Oncology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-160-2_24
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DOI: https://doi.org/10.1007/978-1-59259-160-2_24
Publisher Name: Humana Press, Totowa, NJ
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