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Toxic Substances and Human Risk pp 339–355Cite as

Assessment of the Hazard of Genetic Toxicity

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Abstract

A variety of toxic substances have structural features that permit them to reach the genetic material, where they produce damage. If such damage is not satisfactorily repaired, serious consequences for the organism can ensue. The theoretical and empirical bases for this conclusion are summarized in this chapter.

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Author information

Authors and Affiliations

  1. National Center for Toxicological Research (HFT-1), Jefferson, Arkansas, 72079, USA

    Ronald W. Hart

  2. Division of Molecular Toxicology, Hazelton Laboratories, Kensington, Maryland, 20895, USA

    David Brusick

Authors
  1. Ronald W. Hart
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  2. David Brusick
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Editor information

Editors and Affiliations

  1. Environ Corporation, Washington, D.C., 20007, USA

    Robert G. Tardiff  & Joseph V. Rodricks  & 

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© 1987 Plenum Press, New York

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Hart, R.W., Brusick, D. (1987). Assessment of the Hazard of Genetic Toxicity. In: Tardiff, R.G., Rodricks, J.V. (eds) Toxic Substances and Human Risk. Life Science Monographs. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-5290-7_15

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  • DOI: https://doi.org/10.1007/978-1-4684-5290-7_15

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4684-5292-1

  • Online ISBN: 978-1-4684-5290-7

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