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Intracellular Processes that Affect Renal Phosphate Transport

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Phosphate and Mineral Metabolism

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 178))

Abstract

Studies of phosphate transport in the proximal renal tubule have focused recently on interactions with intracellular processes, especially oxidative metabolism and gluconeogenesis. Intracellular inorganic phosphate is essential for oxidative phosphorylation and participates in mitochondrial respiration. Gluconeogenesis liberates phosphate. This review will summarize our recent observations on changes in phosphate transport with metabolic inhibitors, metabolic substrates and changes in gluconeogenesis.

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References

  • Gullans, S. R., Brazy, P. C., Dennis, V. W., and Mandel, L. J., 1982, Metabolic inhibitors: Effects on metabolism and transport in the proximal tubule, Am. J. Physiol. 243: F133–F140.

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© 1984 Plenum Press, New York

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Dennis, V.W., Brazy, P.C. (1984). Intracellular Processes that Affect Renal Phosphate Transport. In: Massry, S.G., Maschio, G., Ritz, E. (eds) Phosphate and Mineral Metabolism. Advances in Experimental Medicine and Biology, vol 178. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4808-5_2

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  • DOI: https://doi.org/10.1007/978-1-4684-4808-5_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4810-8

  • Online ISBN: 978-1-4684-4808-5

  • eBook Packages: Springer Book Archive

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