Abstract
Several studies have demonstrated the presence of a number of plasma proteins (α-fetoprotein, fetuin, transferrin and albumin) in the developing brain of many different species including rat[1], mouse[2], sheep[3], pig[4] and human[5]. These proteins and some other plasma proteins have been found in high concentrations in cerebrospinal fluid in early stages of brain development[3,4,6–9]. The work described in this paper is concerned with two main questions. 1) Where do the plasma proteins in fetal csf and brain originate from? 2) What is their functional significance?
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
J. Trojan and J. Uriel, C.R.Acad.Sci., 289: 1157–1160 (1979).
C. D. Toran-Allerand, Nature, 286: 733–735 (1980).
K. M. Dziegielewska, et al., J.Physiol., 318: 239–250 (1981).
M. E. Cavanagh, et al., Dev.Neurosci., 5: 492–502 (1982).
K. Msllgrd, et al., Neurosci.Lett., 14: 85–90 (1979).
K. M. Dziegielewska, et al., J.Physiol., 300: 441–445 (1980a).
K. M. Dziegielewska, et al., J.Physiol., 300: 457–465 (1980b).
K. M. Dziegielewska, et al., Dev.Biol., 83: 193–200 (1981).
K. M. Dziegielewska and N. R. Saunders, Comp.Biochem.Physiol., 66B: 307–311 (1981).
M. E. Cavanagh, et al., In preparation (1983).
K. M6llgørd and N. R. Saunders, J.Neurocytol., 4: 453–468 (1975).
J. E. Bottenstein, et al., Exper.Cell Res., 125: 183–190 (1980).
M. Jacobsen, et al., Develop,Brain Res., 3: 239–250 (1982a).
M. Jacobsen, et al., Develop.Brain Res., 3: 251–262 (1982b).
M. Jacobsen, et al., Develop.Brain Res., In press, (1983).
K. Millg$rd, et al., Nature, 264: 5583, 293–294 (1976).
N. R. Saunders and K. M611$rd, Trends.Neurosci., 4: 56–60 (1981).
E. Bock, J.Neurochem., 19: 1731–1736 (1972).
M. E. Cavanagh, et al., Submitted to Dev.Brain Res., (1983).
T. T. Puck, et al., Proc.Nat.Acad.Sci., 59: 192–199 (1968).
S. Yachnin, J.Exp.Med., 141: 242–256 (1975).
K. M. Dziegielewska, et al., Comp.Biochem.Physiol., 76A: 2, 241–245 (1983).
H. G. Coon and C. N. Sinback, in “Growth of Cells in Hormonally Defined Media”, D.A. Sirbasku et al., ed., Cold Spring Harbor, NY, pp 1009–1016 (1982).
M. Ali, et al., Dev.Brain Res., 6: 47–55 (1983).
K. M. Dziegielewska and N. R. Saunders, Comp.Biochem.Physiol., 73A: 2, 327–329 (1982).
R. G. Ham, in “Growth of Cells in Hormonally Defined Media”, D.A.Sirbasku et al., ed., Cold Spring Harbour, NY, pp 39–60 (1982).
M. E. Molliver, et al., Brain Res., 50: 403–407 (1973).
M. W. Brightman and T. S. Reese, J.Cell Biol., 40: 648–677 (1969).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1984 Plenum Press, New York
About this chapter
Cite this chapter
Saunders, N.R. (1984). Plasma Proteins and Fetal Brain Development. In: Duprat, AM., Kato, A.C., Weber, M. (eds) The Role of Cell Interactions in Early Neurogenesis. NATO ASI Series, vol 77. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1203-1_17
Download citation
DOI: https://doi.org/10.1007/978-1-4684-1203-1_17
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-1205-5
Online ISBN: 978-1-4684-1203-1
eBook Packages: Springer Book Archive