Abstract
History records that oxygen was first used for treatment purposes in the United States on March 6, 1887, by Dr George E Holzapple. He used it for a teenager with pneumococcal pneumonia, generating oxygen from chlorate of potassium and black oxide of manganese, producing the life-giving gas in large test tubes heated by a lamp. Holzapple observed the resolution of cyanosis and the reduction in tachypnea in a matter of minutes.
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© 1988 Plenum Press, New York
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Lund, N. (1988). Home Oxygen Therapy. In: Mochizuki, M., Honig, C.R., Koyama, T., Goldstick, T.K., Bruley, D.F. (eds) Oxygen Transport to Tissue X. Advances in Experimental Medicine and Biology, vol 222. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-9510-6_65
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DOI: https://doi.org/10.1007/978-1-4615-9510-6_65
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