Abstract
The terms pseudodementia, dementia syndrome of depression, coexisting dementia and depression, delirious mania and organic affective syndrome have all been used to label the co-occurrence of cognitive impairment and an affective disorder. Each term carries with it a point of view and assumes that cognitive and affective symptoms occur together more often than one would expect by chance and that one set of symptoms is primary. For example, the word pseudodementia implies that the depression (or some other psychiatric disorder) is primary and that the poor cognitive performance is an epiphenomenon of the primary condition; the label cognitive affective disorder (Ancill, 1989), on the other hand, implies that the cognitive disorder is primary and that the affective syndrome is secondary. In an attempt to clarify and objectify these implications and to offer a neutral label for the clinical states in which affective and cognitive symptoms co-occur, Reifler and co-workers (1982) proposed the labels Type 1 and Type 2 for these two possibilities. To date this suggestion has not been taken up by others.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Abas, M.A., Sahakian, B.J. and Levy, R. (1990) Neuropsychological deficits and CT scan changes in elderly depressives. Psychol. Med., 20, 507–20.
Albert, M.L., Feldman, R.G. and Willis, A.L. (1974) The ‘subcortical dementia’ of progressive supranuclear palsy. J. Neurol. Neurosurg. Psychiatry, 37, 121–30.
Alexopoulos, G.S., Young, R.C., Haycox, J.A. et al. (1985) Dexamethasone suppression test in depression with reversible dementia. Psychiatry Res., 16, 277–85.
Ancill, R.J. (1989) Cognitive-affective disorders: The co-presentation of depression and dementia in the elderly. Psychiatr. J. Univ. Ottawa, 14, 370–1.
Baxter, L.R. Jr, Schwartz, J.M., Phelps, M.E. et al. (1989) Reduction of prefrontal cortex glucose metabolism in three types of depression. Arch. Gen. Psychiatry, 46, 243–50.
Benninger, R.J. (1983) The role of dopamine in locomotor activity and learning. Brain Res. Rev., 6, 173–96.
Berrios, G.E. (1985) ‘Depressive pseudodementia’ or ’Melancholic dementia’: a 19th century view. J. Neurol. Neurosurg. Psychiatry, 48, 393–400.
Berrios, G.E. and Freeman, H.L. (1991) Dementia before the twentieth century. In Alzheimer and the Dementias (eds G.E. Berrios and H.L. Freeman ), Henry Ling Ltd, London, pp. 9–27.
Bulbena, A. and Berrios, G.E. (1986) Pseudodementia: Facts and figures. Br. J. Psychiatry, 148, 87–94.
Burt, D.B., Zembar, M.J. and Niederhe, G. Is depression associated with memory impairment? A meta-analysis. Submitted for publication.
Buysse, D.J., Reynolds, C.F. III, Kupfer, D.J. et al. (1988) Electroencephalographic sleep in depressive pseudodementia. Arch. Gen. Psychiatry, 45, 568–75.
Cahn, C. (1991) The history of subcortical dementia. In Alzheimer and the Dementias (eds G.E. Berrios and H.L. Freeman ), Henry Ling Ltd. London, pp. 77–88.
Cassens, G., Wolfe, L. and Zola, M. (1990) The neuropsychology of depression. J. Neuropsychiatry, 2, 202–13.
Christianson, S.A., Loftus, E.F., Hoffman, H. and Loftus, G.R. (1991) Eye fixations and memory for emotional events. J. Exp. Psychol. (Learn. Mem. Cogn.), 17, 693–701.
Cohen, R.M., Weingartner, H., Smallberg, S.A. et al. (1982) Effort and cognitive in depression. Arch. Gen. Psychiatry, 39, 593–7.
Cronholm, B. and Ottosson, J.O. (1961) Memory functions in endogenous depression. Arch. Gen. Psychiatry, 5, 193–9.
Danion, J.M., Willard-Schroeder, D., Zimmermann, M.A. et al. (1991) Explicit memory and repetition priming in depression: Preliminary findings. Arch. Gen. Psychiatry, 48, 707–11.
Dessonville Hill, C., Stoudemire, A., Morris, R. et al. (1992) Dysnomia in the differential diagnosis of major depression, depression-related cognitive dysfunction, and dementia. J. Neuropsychiatry Clin. Neurosci., 4, 64–9.
Ellis, H.C. (1991) Focused attention and depressive deficits in memory. J. Exp. Psychol. (Gen.), 3, 310–12.
Emery, O.B. and Breslau, L.D. (1989) Language deficits in depression: Comparisons with SDAT and normal aging. J. Gerontol., 44, M85–92.
Folstein, M.F. and McHugh, P.R. (1978) Dementia syndrome of depression. In Alzheimer’s Disease: Senile Dementia and Related Disorders (eds R. Katzman, R.D. Terry and K.L. Black ), Raven Press, New York, pp. 87–93.
Friedman, A.S. (1963) Minimal effects of severe depression on cognitive functioning. J. Abnorm. Soc. Psychol. 3, 237–43.
Gibson, A.J. (1981) A further analysis of memory loss in dementia and depression in the elderly. Br. J. Clin. Psychol., 20, 179–85.
Grafman, J., Weingartner, H., Lawlor, B. et al. (1990) Automatic memory processes in patients with dementia-Alzheimer’s disease (DAT). Cortex, 26, 361–71.
Hall, K.R.L. (1952) Conceptual impairment in depressive and organic patients of the pre-senile age group. J. Ment. Sci., 98, 256–65.
Hasher, L. and Zacks, R.T. (1979) Automatic and effortful processes in memory. J. Exp. Psychol. (Gen.), 109, 356–88.
Hemsi, L.K., Whitehead, A. and Post, F. (1968). Cognitive functioning and cerebral arousal in elderly depressives and dements. J. Psychosom. Res., 12, 145–6.
Hertel, L. and Hardin, T.S. (1990) Remembering with and without awareness in a depressed mood: Evidence of deficits in initiative. J. Exp. Psychol. (Gen.), 119, 45–59.
Hertel, P.A. and Rude, S.S. (1991) Depressive deficits in memory: Focusing attention improves subsequent recall. J. Exp. Psychol., 120, 301–9.
Kilbansky, R., Panofsky, E. and Saxl, F. (1964) Saturn and Melancholy, Basic Books, New York, pp. 84. Referred to in Jackson, S.W. ( 1986 ) Melancholia and Depression: From Hippocratic Times to Modern Times, Yale University Press, New Haven.
Kiloh, L.C. (1961) Pseudo-dementia. Acta Psychiatr. Scand., 37, 336–51.
King, D.A., Caine, E.D., Conwell, Y. and Cox, C. (1991) The neuropsychology of depression in the elderly: A comparative study of normal aging and Alzheimer’s disease. J. Neuropsychiatry Clin. Neurosci., 3, 163–8.
Kluger, A. and Goldberg, E. (1990) IQ patterns in affective disorder, lateralized and diffuse brain damage. J. Clin. Exp. Neuropsychol., 12, 182–94.
Kraeplin, E. (1915) Clinical Psychiatry (ed. and trans. A.R. Diefendorf), Macmillan, New York.
Kral, V.A. (1983) The relationship between senile dementia (Alzheimer type) and depression. Can. J. Psychiatry, 28, 304–6.
Kral, V.A. and Emery, O.B. (1989) Long-term follow-up of depressive pseudodementia of the aged. Can. J. Psychiatry, 34, 445–6.
Levy, R. (1969) The neurophysiology of dementia. Br. J. Hosp. Med., 688–90.
Liston, E.H. Jr (1977) Occult presenile dementia. J. Nerv. Ment. Dis., 164, 263–7.
Lowenstein, D.A., D’Elia, L., Guterman, A. et al. (1991) The occurrence of different intrusive errors in patients with Alzheimer’s disease, multiple cerebral infarctions, and major depression. Brain Cogn., 16, 104–17.
McHugh, P.R. (1964) Occult hydrocephalus. Q. J. Med., 33, 297–308.
McHugh, P.R. and Folstein, M.F. (1973) Recent Advances in Dementia. Address to the American Academy of Neurology, April 1973, Boston, MA.
Madden, J.J., Lohan, J.A., Kaplan, L.A. and Manfredi, H.M. (1952) Nondementing psychoses in older persons. JAMA, 150, 1567–70.
Mendez, M.F., Mastri, A.R., Sung, J.H. et al. (1991) Neuropathologically confirmed Alzheimer’s disease: Clinical diagnoses in 374 cases. J. Geriatr. Psychiatry Neurol., 4, 26–9.
Mesulam, M.M. (ed.) (1985) Principles of Behavioral Neurology, F.A. Davis Company, Philadelphia.
Miller, E. and Lewis, P. (1977) Recognition memory in elderly patients with depression and dementia. J. Abnorm. Psychol., 86, 84–6.
Miller, E.K., Li, L. and Desimone, R. (1991) A neural mechanism for working and recognition memory in inferior temporal cortex. Science, 254, 1377–9.
Pearlson, G.D., Rabins, P.V., Kim, W.S. et al. (1989) Structural brain CT changes and cognitive deficits in elderly depressives with and without reversible dementia (’pseudodementia’). Psychol. Med., 19, 573–84.
Post, F. (1966) Somatic and psychic factors in the treatment of elderly psychiatric patients. J. Psychosom. Res., 10, 13–19.
Rabins, P.V., Merchant, A. and Nestadt, G. (1984) Criteria for diagnosing reversible dementia caused by depression: Validation by 2-year follow-up. Br. J. Psychiatry, 144, 488–92.
Reding M.J., Haycox, J. Wigforss, K. et al. (1984) Follow up of patients referred to a dementia service. J. Am. Geriatr. Soc., 32, 265–8.
Reding, M., Haycox, J. and Blass, J. (1985) Depression in patients referred to a dementia clinic: A three-year prospective study. Arch. Neurol., 42, 894–6.
Reifler, B.V., Larson, E. and Hanley, R. (1982) Coexistence of cognitive impairment and depression in geriatric outpatients. Am. J. Psychiatry, 139, 623–66.
Reifler, B.V., Teri, L., Raskind, M. et al. (1989) Double-blind trial of imipramine in Alzheimer’s disease patients with the without depression. Am. J. Psychiatry, 146, 45–9.
Reynolds, C.F., Kupfer, D.J., Hoch, C.C. et al. (1986) Two-year follow-up of elderly patients with mixed depression and dementia. Clinical and electroencephalographic sleep findings. J Am. Geriatr. Soc., 34, 793–9.
Reynolds, C.F. III, Hoch, C.C., Kupfer, D.J. et al. (1988) Bedside differentiation of depressive pseudodementia from dementia. Am. J. Psychiatry, 145, 1099–103.
Shraberg, D. (1978) The myth of pseudodementia: Depression and the aging brain. Am. J. Psychiatry, 135, 601–3.
Silfverskiold, P. and Risberg, J. (1989) Regional cerebral blood flow in depression and mania. Arch. Gen. Psychiatry, 46, 253–9.
Spar, J.E. and Cerner, R. (1982) Does the dexamethasone suppression test distinguish dementia from depression ? Am. J. Psychiatry, 139, 238–40.
Speedie, L., Rabins, P., Pearlson, G.D. and Moberg, P. (1990) Confrontation naming deficits in dementia of depression. J. Neuropsychiatry Clin. Neurosci., 2, 59–63.
Spitzer, H., Desimone, R. and Moran, J. (1988) Increased attention enhances both behavioral and neuronal performance. Science, 240, 338–40.
Sternberg, D. and Jarvik, M.E. (1976) Memory functions in depression. Arch. Gen. Psychiatry, 33, 219–24.
Sunderland, T., Rubinow, D.R., Tariot, P.N. et al. (1987) CSF somatostatin in patients with Alzhei-mer’s disease, older depressed patients, and age-matched control subjects. Am. J. Psychiatry, 144, 1313–16.
Tomlinson, B.E., Blessed, G. and Roth, M. (1968) Observations on the brains of non-demented old people. J. Neurol. Sci., 7, 331–56.
Weingartner, H., Cohen, R.M., Murphy, D.L. et al. (1982) Cognitive processes in depression. Arch. Gen. Psychiatry, 38, 42–7.
Wells, C.E. (1978) Pseudodementia. Am. J. Psychiatry, 136, 894–6.
Wells, F.L. and Martin, H.A.A. (1924) A method of memory examination suitable for psychotic cases. Am. J. Psychiatry, 3, 435–49.
Whitehead, A. (1973) Verbal learning and memory in elderly depressives. Br. J. Psychiatry, 123, 203–8.
Zhang, M., Katzman, R., Salmon, D. et al. (1990) The prevalence of dementia and Alzheimer’s disease in Shanghai, China: Impact of age, gender and education. Ann. Neurol., 27, 428–37.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1994 Springer Science+Business Media Dordrecht
About this chapter
Cite this chapter
Rabins, P.V., Pearlson, G.D. (1994). Depression Induced Cognitive Impairment. In: Burns, A., Levy, R. (eds) Dementia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6805-6_41
Download citation
DOI: https://doi.org/10.1007/978-1-4615-6805-6_41
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4615-6807-0
Online ISBN: 978-1-4615-6805-6
eBook Packages: Springer Book Archive