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Single Photon Emission Tomography

  • Chapter
Dementia

Abstract

Functional brain imaging with single photon emission tomography (SPET), also known as single photon emission computed tomography (SPECT), enables three-dimensional images of regional cerebral blood flow to be derived from two-dimensional data. Positron emission tomography (PET) can be used to measure regional cerebral metabolism and neurotransmitter receptor characteristics in addition to rCBF. It sets the standards for spatial resolution by which SPET is judged. However, PET requires sophisticated and expensive technology, including a cyclotron on site, and has little prospect of general clinical application. In contrast, SPET is relatively inexpensive and is widely available for clinical use. The radiotracers used in SPET emit a single gamma ray (or photon), as opposed to the dual simultaneous gamma rays of PET radiotracers, hence the term ‘single photon’ in SPET. There have now been a number of SPET studies investigating changes in rCBF in dementia.

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Authors
  1. D. P. Geaney
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Editors and Affiliations

  1. University of Manchester, UK

    Alistair Burns (Professor of Old Age Psychiatry) (Professor of Old Age Psychiatry)

  2. Institute of Psychiatry, London, UK

    Raymond Levy (Professor of Old Age Psychiatry) (Professor of Old Age Psychiatry)

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© 1994 Springer Science+Business Media Dordrecht

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Geaney, D.P. (1994). Single Photon Emission Tomography. In: Burns, A., Levy, R. (eds) Dementia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6805-6_25

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  • DOI: https://doi.org/10.1007/978-1-4615-6805-6_25

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-6807-0

  • Online ISBN: 978-1-4615-6805-6

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