Abstract
The cortex of the cerebellum is made up by only a few different types of neurons which are arranged in a highly regular and geometrical way. Because of its unusual regularity the cerebellar cortex has attracted many theoreticians and experimentalists, and research on the cerebellum has now been done for more than a hundred years. As a result, the cerebellum is today in many respects one of the best described parts of the vertebrate brain. Its anatomical structure has been well known since the beginning of the century, electrophysiology started in the sixties (Eccles et al. 1967) and was continued since then with increasing intensity. In spite of that, however, we are not yet able to relate the anatomical structure and the neuronal activity of the cerebellum to what is widely considered its main function: the control of posture and movement.
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References
BOWER, J. M. & WOOLSTON, D. C. (1983). Congruence of Spatial Organization of Tactile Projections to Granule Cell and Purkinje Cell Layers of Cerebellar Hemispheres of the Albino Rat: Vertical Organization of Cerebellar Cortex. J. Neurophysiol. 49, 745–766.
BRAITENBERG, V. (1961). Functional Interpretation of Cerebellar Histology. Nature 190, 539–540.
BRAITENBERG, V. (1967). Is the Cerebellar Cortex a Biological Clock in the Millisecond Range? In Progress in Brain Research. Vol. 25. The Cerebellum, eds. FOX, C. A. & SNIDER, R. S. pp. 334–346. Amsterdam: Elsevier.
BRAITENBERG, V. (1976). Real Neural Networks. In Perspectives in Brain Research, eds. CORNER, M. A. & SWAAB, D. F. pp. 197–205. Amsterdam: Elsevier.
BRAITENBERG, V. (1978). Cortical Architectonics: General and Areal. In Architectonics of the Cerebral Cortex, 443–465. New York: Raven Press.
BRAITENBERG, V. (1983). The cerebellum revisited. Journal of Theoretical Neurobiology 2, 237–241.
BRAITENBERG, V. (1987). The cerebellum and the physics of movement: some speculations. In Cerebellum and neuronal plasticity, eds. GLICKSTEIN, M., YEO, C. & STEIN, J. pp. 193–207. New York: Plenum.
BRAITENBERG, V. & ATWOOD, R. P. (1958). Morphological observations on the cerebellar cortex. J. Comp. Neurol. 109, 1–33.
BRAITENBERG, V. & SCHÜZ, A. (1991). Anatomy of the Cortex. Statistics and Geometry. Berlin,Heidelberg, New York: Springer Verlag.
ECCLES, J. C., LLINÁS, R. & SASAKI, K. (1966). The excitatory synaptic action of climbing fibres on the Purkinje cells of the cerebellum. J. Physiol. (Lond.) 182, 268–296.
ECCLES, J. C., ITO, M. & SZENTÁGOTHAI, J. (1967). The Cerebellum as a Neuronal Machine. Berlin: Springer.
EKEROT, C.-F. & OSCARSSON, O. (1981). Prolonged depolarization elicited in Purkinje cell dendrites by climbing fiber impulses in the cat. J. Physiol. (Lond.) 318, 207–221.
GILBERT, P. F. C. (1975). How the cerebellum could memorize movements. Nature 254, 688–689.
GRANIT, R. & PHILLIPS, C. G. (1956). Excitatory and inhibitory processes acting upon individual Purkinje cells of the cerebellum in cats. J. Physiol. (Lond.) 133, 520–547.
HECK, D. (1993a). Rat cerebellar cortex in vitro responds specifically to moving stimuli. Neurosci. Lett. 157, 95–98.
HECK, D. (1993b). Specific responses of the cerebellar cortex to moving stimuly. In Brain Theory: Spacio-Temporal Aspects of Brain Function, ed. AERTSEN, A. M. H. J. pp. 127–130. Amsterdam: Elsevier.
HECK, D. (1994). Making sense of parallel fibers: further experimental evidence for the interpretation of the cerebellum as a sequence addressable memory. Proceedings of the 22th Göttingen Neurobiology Conference 565 (Abstract)
HECK, D. (1995a). Die Bedeutung raum-zeitlicher Dynamik für die Aktivität des Kleinhirnkortex und die Interpretation seiner Anatomie. Hamburg: Verlag Dr. Kovac.
HECK, D. (1995b). Investigating dynamic aspects of brain function in slice preparations: Spatiotemporal stimulus patterns generated with an easy to build multi-electrode array. J. Neurosci. Methods 58, 81–87.
HECK, D. (1995c). Sequential input to guinea pig cerebellar cortex in vitro strongly affects Purkinje cells via parallel fibers. Naturwissenschaften 82, 201–203.
HECK, D. & BRAITENBERG, V (1993). Specific Responses of Rat Cerebellar Cortex to Moving Input: Dependence of Distance Covered by the Movement. Soci.Neurosci.Abstr. 19, 1589 (Abstract)
HORE, J., WILD, B. & DIENER, H. C. (1991). Cerebellar dysmetria at the elbow, wrist and fingers. J. Neurophysiol. 65, 563–571.
IVRY, R. (1993). Cerebellar involvement in the explicit representation of temporal information. Ann.NY Acad.Sci. 682, 214–230.
LLINÁS, R., BLOEDEL, J. R. & HILLMAN, D. E. (1969). Functional characterization of neuronal circuitry of frog cerebellar cortex. J. Neurophysiol. 32, 847–870.
LLINÁS, R. (1982). Radial Connectivity in the Cerebellar Cortex: A Novel View Regarding the Functional Organization of the Molecular Layer. In The Cerebellum, New Vistas, eds. PALAY, S. L. & CHAN-PALAY, V. pp. 189–192. New York: Springer.
LLINÁS, R. & SUGIMORI, M. (1992). The Electrophysiology of the Cerebellar Purkinje Cell Revisited. In The Cerebellum Revisited, eds. LLINÁS, R. & SOTELO, C. pp. 167–181. New York: Springer.
NAPPER, R. M. A. & HARVEY, R. J. (1988). Number of parallel fiber synapses on an individual Purkinje cell in the cerebellum of the rat. J. Comp. Neurol. 274, 168–177.
RAMON Y, CAJAL, S. (1911). Histologie du système nerveux de l’homme et des vertébrés. Vol. II. Paris: A. Maloine.
THACH, W. T. (1968). Discharge of cerebellar Purkinje and nuclear neurons during rapidly alternating arm movements in the monkey. J. Neurophysiol. 31, 785–797.
THACH, W. T. (1970). Discharge of cerebellar neurons related to two maintained postures and two prompt movements. II. Purkinje cell output and input. J. Neurophysiol. 33, 537–547.
TROMMALD, M., JENSEN, V & ANDERSEN, P. (1995). Analysis of dendritic spines in rat CA1 pyramidal cells intracellularly filled with a fluorescent dye. J. Comp.Neurol. 353, 260–274.
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Heck, D.H. (1996). The Functional Significance of Cerebellar Anatomy. In: Torre, V., Conti, F. (eds) Neurobiology. NATO ASI Series, vol 289. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5899-6_24
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DOI: https://doi.org/10.1007/978-1-4615-5899-6_24
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