Abstract
In the pancreas, frozen section consultations are commonly used to provide real-time input to surgeons. There are several benign and neoplastic entities commonly encountered within these intraoperative specimens. Frequently encountered entities include chronic pancreatitis, pancreatic ductal adenocarcinoma, pancreatic endocrine tumors, mixed exocrine-endocrine carcinomas, solid pseudopapillary tumors, acinar cell carcinomas, lymphoproliferative disorders, and metastatic diseases. These entities can be found in varying degrees within the head, body, or tail of the pancreas. Frozen section diagnoses can help to answer questions which are imperative for the correct course of treatment. Is the mass an inflammatory or a neoplastic process? If neoplastic, is it benign or malignant? What type of neoplasm might it be? Does it extend to the resection margin? Is it a metastasis? To answer these questions, a variety of specimen types may be submitted including needle core biopsies, wedge resections, resection margin biopsies, lymph nodes, or entire pancreaticoduodenectomy (the Whipple procedure) resection specimens.
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Turner, K., Zhai, Q.“., Sutton, J.M., Ahmad, S. (2014). Endocrine Tumors of the Pancreas. In: Zhai, Q. (eds) Frozen Section Library: Endocrine Organs. Frozen Section Library, vol 12. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8612-1_3
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DOI: https://doi.org/10.1007/978-1-4614-8612-1_3
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