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Animal Diseases, Applications of Metagenomics

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Encyclopedia of Metagenomics

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Synonyms

Infectious diseases in animals; Livestock; Mice and dogs

Definition

This entry describes current knowledge about the microbiome of the gastrointestinal tract of animals and its relationship to infectious diseases. It also describes how the microbiome changes during infections.

Introduction

Rene Dubos’ pioneering work on microbial ecology led to the hypothesis that the microbes of mammals living in intimate contact with each other coevolved with animals (Dubos et al. 1965; Yolton and Savage 1976). Dubos stated, “It is to be expected, therefore, that anatomical structures and physiological needs have been determined in part by the microbiota (microbiome) which prevailed during evolutionary development, and that many manifestations of the body at any given time are influenced by the microbiota now present.” Thus, during the coevolution of the microflora and the host, a set of mutualistic or even symbiotic relationships developed between the host and microbes. This hypothesis is...

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Authors and Affiliations

  1. Department of Veterinary and Biomedical Sciences, University of Minnesota, 1971 Commonwealth Avenue, St. Paul, MN, 55108, USA

    Richard Isaacson

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  1. Richard Isaacson
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Correspondence to Richard Isaacson .

Editor information

Editors and Affiliations

  1. J. Craig Venter Institute (JCVI), Rockville, Maryland, USA

    Karen E. Nelson

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© 2013 Springer Science+Business Media New York

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Isaacson, R. (2013). Animal Diseases, Applications of Metagenomics. In: Nelson, K. (eds) Encyclopedia of Metagenomics. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6418-1_18-6

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  • DOI: https://doi.org/10.1007/978-1-4614-6418-1_18-6

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  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-6418-1

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