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The Quantity and Rate of Calcium Uptake in Normal and Hypertrophied Hearts

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Pathophysiology of Heart Disease

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 65))

Abstract

The pump performance of the heart depends on the contractile characteristics of the myocytes and the geometric organization of the myocytes to make up the macroscopic pump structure. Under steady state conditions the beat to beat force which the myocytes contribute to the development of intraventricular pressure depends on the following: 1) excitation contraction coupling (ECC) events; 2) the integrity of the contractile system (actin and myosin); and 3) high energy phosphate stores and production. This review addresses some aspects of the excitation contraction coupling events.

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References

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Author information

Authors and Affiliations

  1. Department of Physiology and Biophysics, University of Vermont, College of Medicine, Burlington, Vermont, 05405, USA

    Norman R. Alpert, Edward M. Blanchard & Louis A. Mulieri

Authors
  1. Norman R. Alpert
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  2. Edward M. Blanchard
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  3. Louis A. Mulieri
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Editor information

Editors and Affiliations

  1. Department of Physiology, Youville Research Institute, St. Boniface General Hospital and University of Manitoba, Winnipeg, Canada

    Naranjan S. Dhalla , Pawan K. Singal  & Robert E. Beamish ,  & 

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© 1987 Martinus Nijhoff Publishing, Boston

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Alpert, N.R., Blanchard, E.M., Mulieri, L.A. (1987). The Quantity and Rate of Calcium Uptake in Normal and Hypertrophied Hearts. In: Dhalla, N.S., Singal, P.K., Beamish, R.E. (eds) Pathophysiology of Heart Disease. Developments in Cardiovascular Medicine, vol 65. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2051-7_7

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  • DOI: https://doi.org/10.1007/978-1-4613-2051-7_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9219-7

  • Online ISBN: 978-1-4613-2051-7

  • eBook Packages: Springer Book Archive

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