Abstract
In 1962, when I completed my Ph.D. at Columbia under Charlie’s supervision, jobs for physicists were plentiful. It seemed to me like a good opportunity to try something that interested me in a general way, but about which I knew very little. I asked Charlie’s advice about whether to take a job in biophysics. He replied that it was worth a try, if I were interested, but that it would be prudent to set a deadline of 2 or 3 years to decide whether to continue or to return to the area of my basic training. I followed that advice, considered several areas of biophysics, and took a job at the National Institutes of Health (NIH) in Bethesda, Maryland in a laboratory started by another physicist, Kenneth Cole. My early work at NIH was on the squid giant axon, which was then the standard preparation for studying the electrical properties of nerves. I found the work quite interesting, and have remained at NIH for 33 years. (By Charlie’s standards, I am now at about mid-career.)
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References
A. D. Roses and J. Neuropathol, Exp. Neurol. 53, 429 (1994).
D. J. Selkoe and J. Neuropathol, Exp. Neurol. 53, 438 (1994).
B. T. Hyman and R. D. Terry, J. Neuropathol. Exp. Neurol. 53, 427 (1994).
A. Goate, et al, Nature 349, 704 (1991).
S. E. Arnold, B. T. Hyman, J. Flory, A. R. Damasio, and H. G. Van, Cereb. Cortex 1, 103 (1991).
P. V. Arriagada, J. H. Growdon, W. E. Hedley, and B. T. Hyman, Neurology 42, 631 (1992).
W. J. Strittmatter, etal, Proc. Natl. Acad. Sci. U.S.A. 90, 1977 (1993).
E. H. Corder, et al, Nat. Genet. 7, 180 (1994).
H. L. West, G. W. Rebeck, and B. T. Hyman, Neurosci. Lett. 175, 46 (1994).
K. L. Davis, etal, Psychopharmacol. Bull. 18, 193 (1982).
M. J. Knapp, et al, Jama 271, 985 (1994).
R. C. Mohs, et al, J. Am. Geriatr. Soc. 33, 749 (1985).
T. A. Slotkin, et al, Proc. Natl. Acad. Sci. U. S. A. 87, 2452 (1990).
J. A. Hardy, and G. A. Higgins, Science 256, 184 (1992).
W. J. Strittmatter, etal, Exp. Neurol. 125, 163 (1994).
Y. Namba, M. Tomonaga, H. Kawasaki, E. Otomo, and K. Ikeda, Brain Res. 541, 163 (1991).
M. P. Mattson, et al, J. Neurosci. 12, 376 (1992).
R. Joseph, and E. Han, Biochem. Biophys. Res. Commun. 184, 1441 (1992).
R. Etcheberrigaray, E. Ito, C. S. Kim, and D. L. Alkon, Science 264, 276 (1994).
N. Arispe, E. Rojas, and H. B. Pollard, Proc. Natl. Acad. Sci. U.S.A. 90, 567 (1993).
Z. Galdzicki, R. Fukuyama, K. C. Wadhwani, S. I. Rapoport, and G. Ehrenstein, Brain Res. 646, 332 (1994).
R. Fukuyama, K. C. Wadhwani, Z. Galdzicki, S. I. Rapoport, and G. Ehrenstein, Brain Res. 667, 269 (1994).
R. J. Wurtman, Trends Neurosci. 15, 117 (1992).
M. Ando, M. Iwata, K. Takahama, and Y. Nagata, J. Neurochem. 48, 1448 (1987).
R. J. Wurtman, et al, Adv. Neurol. 51, 117 (1990).
A. Y. Hung, et al, J. Biol. Chem. 268, 22959 (1993).
J. D. Buxbaum, A. A. Ruefli, C. A. Parker, A. M. Cypess, and P. Greengard, Proc. Natl. Acad. Sci. U.S.A. 91, 4489 (1994).
G. Ehrenstein, and Z. Galdzicki, Biophys. J. 68, A126 (1995).
S. H. Appel, Ann. Neurol. 10, 499 (1981).
R. M. Nitsch, etal, Proc. Natl. Acad. Sci. U.S.A. 89, 1671 (1992).
R. Elble, E. Giacobini, and C. Higgins, Neurobiol. Aging 10, 45 (1989).
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Ehrenstein, G. (1996). Searching for the Cause of Alzheimer’s Disease. In: Chiao, R.Y. (eds) Amazing Light. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2378-8_21
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