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Gastric Cancer

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Abstract

22,710 new cases and 11,780 deaths from gastric cancer each year in the US. Highest death rates are reported in Chile, Costa Rica, Japan, China, and the former Soviet Union. Median age of diagnosis is 65. Male:female = 1.5:1. Etiology and possible risk factors: low fruits and vegetables, high salts and nitrates, salted fish, smoked meats, Helicobacter pylori, hypochlorohydria, polyps, genetic alterations (p53 mutation, microsatellite instability, E-cadherin gene), previous radiation, gastrectomy, and pernicious anemia.

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Acknowledgement

We thank Richard M. Krieg, MD, for his valuable ­advice in the preparation of this chapter.

Author information

Authors and Affiliations

  1. Radiation Medicine, Oregon Health and Science University, Portland, OR, USA

    Charlotte Dai Kubicky MD, PhD

  2. Radiation Oncology, University of California San Francisco, San Francisco, CA, USA

    Jennifer S. Yu MD, PhD

  3. Radiation Oncology, Sunnybrook Odette Cancer Centre, University of Toronto, Toronto, ON, Canada

    Hans T. Chung MD

Authors
  1. Charlotte Dai Kubicky MD, PhD
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  2. Jennifer S. Yu MD, PhD
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  3. Hans T. Chung MD
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Editor information

Editors and Affiliations

  1. Div. Radiation Oncology, Oregon Clinic, SW. Barnes Rd. 9205, Portland, 97225, Oregon, USA

    Eric K. Hansen

  2. Department of Radiation Oncology, University of California, San Francisco, Divisadero Street, Suite H-1031 1600, San Francisco, 94143, California, USA

    Mack Roach

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© 2010 Springer-Verlag New York

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Kubicky, C.D., Yu, J.S., Chung, H.T. (2010). Gastric Cancer. In: Hansen, E., Roach, M. (eds) Handbook of Evidence-Based Radiation Oncology. Springer, New York, NY. https://doi.org/10.1007/978-0-387-92988-0_19

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  • DOI: https://doi.org/10.1007/978-0-387-92988-0_19

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