Skip to main content

Retinal Image Registration for NIH’s ETDRS

  • Conference paper
  • 1745 Accesses

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 3804))

Abstract

This paper presents a retinal image registration approach for National Institute of Health (NIH)’s Early Treatment Diabetic Retinopathy Study (ETDRS) standard. The ETDRS imaging protocol specifies seven fields of each retina and presents several major challenges for image registration. The proposed method effectively combines both area-based and feature-based methods in three steps. First, the vascular tree is extracted by using a local entropy thresholding technique. Next, zeroth-order translation is estimated by maximizing mutual information based on the binary image pair (area-based). Specifically, a local entropy-based peak selection and a multi-resolution searching schemes are developed to improve accuracy and efficiency of translation estimation. Third, we use two types of features (feature-based), landmark points and sampling points, for affine/quadratic model estimation. Simulation on 504 pairs of ETDRS retinal images shows the effectiveness of the proposed algorithm.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Zana, F., Klein, J.: A multimodal registration algorithm of eye fundus images using vessels detection and hough transform. IEEE Trans. Biomedical Engineering 18, 419–428 (1999)

    Google Scholar 

  2. Can, A., Stewart, C.V., Roysam, B., Tanenbaum, H.L.: A feature-based, robust, hierarchical algorithm for registering pairs of images of the curved human retina. IEEE Trans. Pattern Anal. Machine Intell. 24, 347–364 (2002)

    Article  Google Scholar 

  3. Stewart, C.V., Tsai, C.L., Roysam, B.: The dual-bootstrap iterative closest point algorithm with application to retinal image registration. IEEE Trans. Med. Imag. 22, 1379–1394 (2003)

    Article  Google Scholar 

  4. Maes, F., Collignon, A., Vandermeulen, D., Marchal, G., Suetens, P.: Multi-modality medical image registration by maximization of mutual information. IEEE Trans. Medical Imaging 16, 187–198 (1997)

    Article  Google Scholar 

  5. Besl, P.J., McKay, N.D.: A method for registration of 3-d shape. IEEE Trans. Pattern Anal. Machine Intell. 14, 239–256 (1992)

    Article  Google Scholar 

  6. Sawhney, H.S., Kumar, R.: True multi-image alignment and its application to mosaicing and lens distortion correction. IEEE Trans. Pattern Analysis and Machine Intelligence 21, 235–243 (1999)

    Article  Google Scholar 

  7. Chaudhuri, S., Chatterjee, S., Katz, N., Nelson, M., Goldbaum, M.: Detection of blood vessels in retinal images using two-dimensional matched filters. IEEE Trans. Medical Imaging 8, 263–269 (1989)

    Article  Google Scholar 

  8. Pal, N.R., Pal, S.K.: Entropic thresholding. Signal processing 16, 97–108 (1989)

    Article  MathSciNet  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Chanwimaluang, T., Fan, G. (2005). Retinal Image Registration for NIH’s ETDRS. In: Bebis, G., Boyle, R., Koracin, D., Parvin, B. (eds) Advances in Visual Computing. ISVC 2005. Lecture Notes in Computer Science, vol 3804. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11595755_7

Download citation

  • DOI: https://doi.org/10.1007/11595755_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-30750-1

  • Online ISBN: 978-3-540-32284-9

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics