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Influence of Metal Ions on the Activity of Soil Humic-Enzyme Complexes

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Use of Humic Substances to Remediate Polluted Environments: From Theory to Practice

Part of the book series: NATO Science Series ((NAIV,volume 52))

Abstract

In the present work, we attempted to elucidate the mechanisms of soil humic acids associations with some proteases. The stability of humic-enzyme complexes and the ways humic acids influence the activity of enzymes were determined. It was shown that humic acids are non-specific inhibitors of proteases. Enzyme-inhibitor complexes are formed by electrostatic, hydrophobic and other types of intermolecular interactions. The protease inhibiting ability of humic acids is influenced by their interaction with metal ions. The stability of enzyme-inhibitor complexes that form by association of proteases with humic-metal complexes depends on the nature of the metals and on the number of coordination centres on the polymeric chains of humic acids.

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Author information

Authors and Affiliations

  1. Institute of Chemistry and Chemical Technology, NAS of Kyrgyz Republic, Chui prospect, 267, 720071, Bishkek, Kyrgyzstan

    S. Jorobekova, K. Kydralieva & E. Hudaybergenova

Authors
  1. S. Jorobekova
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  2. K. Kydralieva
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  3. E. Hudaybergenova
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Editor information

Editors and Affiliations

  1. Lomonosov Moscow State University, Moscow, Russia

    Irina V. Perminova

  2. University of Florida, Gainesville, FL, USA

    Kirk Hatfield

  3. Institute of Ecological Chemistry, GSF-Research Center for Environmental Health, Neuherberg, Germany

    Norbert Hertkorn

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Jorobekova, S., Kydralieva, K., Hudaybergenova, E. (2005). Influence of Metal Ions on the Activity of Soil Humic-Enzyme Complexes. In: Perminova, I.V., Hatfield, K., Hertkorn, N. (eds) Use of Humic Substances to Remediate Polluted Environments: From Theory to Practice. NATO Science Series, vol 52. Springer, Dordrecht. https://doi.org/10.1007/1-4020-3252-8_16

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