Mass spectrometry-based proteomics: advances in data processing

Mass spectrometry, an analytical technique to measure the mass-to-charge ratio of ions in a biological sample, is an indispensable tool in large-scale studies of the proteome. It allows to identify and obtain structural information on proteins based on the unique fragmentation the sample is subjected to. While the principles of mass spectrometry date back to the late 19th-early 20th century, the field experienced tremendous advances since then and has recently gained renewed importance with the advent of the omics and high-throughput approaches. This Collection welcomes submissions on novel computational approaches, software and statistical methods for the analysis of mass spectrometry data for proteomics.