Cell stress responses during COVID19: Exploring pathogenic links and therapeutics

The current pandemic has stimulated research about a group of viruses that includes the human respiratory viruses known as SARS viruses. The pathology of these viruses is very unusual in that many of the symptoms and organ damage caused by these viruses is beyond the primary sites of infection in the respiratory tract and lungs of victims. Early on, investigators in the cell stress response field began observing similarities among COVID19 and chronic cell stress response pathologies. In addition, other investigators suspected that the cellular and tissue states of cytoprotection, a potent and transient cellular defense system present in humans and other organisms, may provide novel opportunities for new therapeutics against SARS viruses. This collection of original articles and current reviews describes state of the art research and hypotheses exploring these links.

Articles (15 in this collection)