Collection
N6-methyladenosine modification in cancer
In this cross-journal collection, we welcome a wide range of articles on the role of N6-methyladenosine in cancer including primary research articles, method-based articles, reviews, and perspectives. N6-methyladenosine (m6A) is a modified mRNA, methylated at the N6-position of adenosine, recently shown as one of the most modification of mRNA and playing an important role in stimulating tumor promotion and inhibiting tumor suppression. Thus, modification and abnormal levels of N6-Methyladenosine play an important role in cancer development and progression. For example, m6A plays a role in AML, breast cancer, ovarian cancer pancreatic and renal cell cancer. Nevertheless, our insight in the complex ways of the mechanisms of tumor-regulation is still very incomplete.
The accompanying collection of articles represents key research in this area from the journals Oncogene, Oncogenesis, Cancer Cell International, and Journal of Cancer Research and Clinical Oncology. The editors welcome future submissions to expand this collection further.
Articles (40 in this collection)
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Comprehensive immunohistochemical analysis of N6-methyladenosine (m6A) writers, erasers, and readers in endometrial cancer
Authors (first, second and last of 9)
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The m6A reading protein YTHDF3 potentiates tumorigenicity of cancer stem-like cells in ocular melanoma through facilitating CTNNB1 translation
Authors (first, second and last of 12)
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METTL3 promotes intrahepatic cholangiocarcinoma progression by regulating IFIT2 expression in an m6A-YTHDF2-dependent manner
Authors (first, second and last of 9)
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YTHDF2 promotes multiple myeloma cell proliferation via STAT5A/MAP2K2/p-ERK axis
Authors (first, second and last of 8)
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The prognosis biomarkers based on m6A-related lncRNAs for myeloid leukemia patients
Authors (first, second and last of 7)
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METTL3 promotes lung adenocarcinoma tumor growth and inhibits ferroptosis by stabilizing SLC7A11 m6A modification
Authors (first, second and last of 7)
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Hypoxia-mediated YTHDF2 overexpression promotes lung squamous cell carcinoma progression by activation of the mTOR/AKT axis
Authors (first, second and last of 5)
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Systematic analyses of the role of prognostic and immunological EIF3A, a reader protein, in clear cell renal cell carcinoma
Authors (first, second and last of 6)
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Emerging role of m6A methylation modification in ovarian cancer
Authors (first, second and last of 7)
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KIAA1429 is a potential prognostic marker in colorectal cancer by promoting the proliferation via downregulating WEE1 expression in an m6A-independent manner
Authors (first, second and last of 12)
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Stabilization of UCA1 by N6-methyladenosine RNA methylation modification promotes colorectal cancer progression
Authors (first, second and last of 11)
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miR-151a-3p-rich small extracellular vesicles derived from gastric cancer accelerate liver metastasis via initiating a hepatic stemness-enhancing niche
Authors (first, second and last of 18)
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Effects of RNA methylation N6-methyladenosine regulators on malignant progression and prognosis of melanoma
Authors (first, second and last of 9)
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The m6A methyltransferase METTL3 controls epithelial-mesenchymal transition, migration and invasion of breast cancer through the MALAT1/miR-26b/HMGA2 axis
Authors (first, second and last of 5)
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Identification of a robust signature for clinical outcomes and immunotherapy response in gastric cancer: based on N6-methyladenosine related long noncoding RNAs
Authors (first, second and last of 6)
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Recent advances of m6A methylation modification in esophageal squamous cell carcinoma
Authors (first, second and last of 9)
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M6A methylation of DEGS2, a key ceramide-synthesizing enzyme, is involved in colorectal cancer progression through ceramide synthesis
Authors (first, second and last of 8)
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N6-methyladenosine demethylase ALKBH5 suppresses malignancy of esophageal cancer by regulating microRNA biogenesis and RAI1 expression
Authors (first, second and last of 9)
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The functions and prognostic values of m6A RNA methylation regulators in thyroid carcinoma
Authors (first, second and last of 6)
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IDH2 contributes to tumorigenesis and poor prognosis by regulating m6A RNA methylation in multiple myeloma
Authors (first, second and last of 11)
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Identification and validation of lncRNAs involved in m6A regulation for patients with ovarian cancer
Authors (first, second and last of 5)
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FTO downregulation mediated by hypoxia facilitates colorectal cancer metastasis
Authors (first, second and last of 17)
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N6-methyladenosine demethyltransferase FTO-mediated autophagy in malignant development of oral squamous cell carcinoma
Authors (first, second and last of 13)
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YTHDF2 is a potential target of AML1/ETO-HIF1α loop-mediated cell proliferation in t(8;21) AML
Authors (first, second and last of 9)
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METTL3-mediated m6A methylation of SPHK2 promotes gastric cancer progression by targeting KLF2
Authors (first, second and last of 6)
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Role of m6A methyltransferase component VIRMA in multiple human cancers (Review)
Authors (first, second and last of 4)
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Comprehensive analysis of the transcriptome‐wide m6A methylome in invasive malignant pleomorphic adenoma
Authors (first, second and last of 6)
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Decreased expression of METTL14 predicts poor prognosis and construction of a prognostic signature for clear cell renal cell carcinoma
Authors (first, second and last of 6)
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Metformin exhibits antiproliferation activity in breast cancer via miR-483-3p/METTL3/m6A/p21 pathway
Authors (first, second and last of 11)
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Emerging role of long noncoding RNA-encoded micropeptides in cancer
Authors (first, second and last of 5)
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Increased expression of YTHDF1 and HNRNPA2B1 as potent biomarkers for melanoma: a systematic analysis
Authors (first, second and last of 4)
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Deoxycholic acid modulates the progression of gallbladder cancer through N6-methyladenosine-dependent microRNA maturation
Authors (first, second and last of 15)
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YTHDF2 promotes the liver cancer stem cell phenotype and cancer metastasis by regulating OCT4 expression via m6A RNA methylation
Authors (first, second and last of 10)
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Novel positioning from obesity to cancer: FTO, an m6A RNA demethylase, regulates tumour progression
Authors
