Maintenance of genome integrity under physical constraints
- Submission status
- Open for submission from
- 01 March 2022
- Submission deadline
Philipp Oberdoerffer is an Associate Professor of Radiation Oncology and Molecular Radiation Sciences at the Johns Hopkins School of Medicine. His laboratory investigates how the epigenetic control of genome maintenance determines the cellular response to DNA damage, and ultimately malignant transformation. Philipp received his Ph. D. in mouse genetics and immunology from the University of Cologne, Germany, and went on to pursue studies on the molecular biology of aging as a postdoc at Harvard Medical School.
Evi Soutoglou is a Research Professor at the Genome Damage and Stability Centre of Sussex University. Her lab is interested in how chromatin and nuclear structure affects DNA repair processes and has used CRSIP/Cas9 targeting and other tools for studying DSBs at specific chromatin contexts. Evi Soutoglou received her PhD from the University of Crete, Greece and she was trained in tissue-specific gene regulation. As a post-doc at the National Cancer Institute (NCI) at NIH, she focused her attention to the emerging role of chromatin structure in DNA repair. Her work provided new insights into the cellular properties of DSBs.