Abstract
The mobilization of adipose tissue of dairy cows during early lactation is reflected by increased fatty acid (FA) plasma concentrations. The capacity of the liver for complete oxidation of non-esterified FA (NEFA) is limited leading to an increased formation of ketone bodies, re-esterification, and accumulation of triacylglycerides in the liver. This is accompanied by a lower feed intake and a high incidence of metabolic disorders (Drackley et al., 2005). The skeletal muscle may also oxidize FA and thus relieve the liver from FA load. Here we hypothesized that skeletal muscle FA degradation adapts to the extent of fat mobilization during early lactation.
Keywords
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Brennan, K.M., J.J. Michal, J.J. Ramsey and K.A. Johnson, 2009. Body weight loss in beef cows: I. The effect of increased beta-oxidation on messenger ribonucleic acid levels of uncoupling proteins two and three and peroxisome proliferator-activated receptor in skeletal muscle. J. Anim. Sci. 87, 2860–2866.
Drackley, J.K., H.M. Dann, G.N. Douglas, N.A. Janovick-Guretzky, N.B. Litherland, J.P. Underwood and J.J. Loor, 2005. Physiological and pathological adaptations in dairy cows that may increase susceptibility to periparturient diseases and disorders. Ital. J. Anim. Sci. 4, 323–344.
De Lange, P., M. Moreno, E. Silvestri, A. Lombardi, F. Goglia and A. Lanni, 2007. Fuel economy in food-deprived skeletal muscle: signaling pathways and regulatory mechanisms. FASEB J. 21, 3431–3441.
Acknowledgements
Supported by DFG, Germany
Author information
Authors and Affiliations
Corresponding author
Editor information
Rights and permissions
Copyright information
© 2013 Wageningen Academic Publishers The Netherlands
About this chapter
Cite this chapter
Schäff, C., Hammon, H.M., Röntgen, M., Kuhla, B. (2013). Skeletal muscle fatty acid oxidation in lactating dairy cows during early lactation. In: Oltjen, J.W., Kebreab, E., Lapierre, H. (eds) Energy and protein metabolism and nutrition in sustainable animal production. Energy and protein metabolism and nutrition in sustainable animal production, vol 134. Wageningen Academic Publishers, Wageningen. https://doi.org/10.3920/978-90-8686-781-3_175
Download citation
DOI: https://doi.org/10.3920/978-90-8686-781-3_175
Publisher Name: Wageningen Academic Publishers, Wageningen
Online ISBN: 978-90-8686-781-3
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)