Severe Asthma

From ICU to Discharge
  • Brian M. Morrissey
  • Nicholas J. Kenyon
  • Timothy E. Albertson
Part of the Current Clinical Practice book series (CCP)


  • The in-hospital mortality rate for all patients with asthma is less than 1%, but for patients with near-fatal asthma who require intubation, the mortality rate may be as high as 5%.

  • Near-fatal asthma refers to a life-threatening asthma attack that requires ventilatory support; status asthmaticus refers to an asthma attack that does not readily respond to aggressive standard treatment.

  • /gb-agonists remain the main pharmacotherapy in status asthmaticus and near-fatal asthma (NFA).

  • African-Americans, women, and the elderly are at increased risk of fatal asthma.

  • Controlled modes of ventilation that allow for a prolonged expiratory time are favored in patients with NFA.

  • General anesthesia by either intravenous infusion or gas inhalation are therapeutic options for the patients with the most severe asthma.

  • Coordination of discharge and follow-up care can safely reduce length of hospital stay.


Intensive Care Unit Continuous Positive Airway Pressure Severe Asthma Respir Crit Acute Asthma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Humana Press Inc. 2006

Authors and Affiliations

  • Brian M. Morrissey
    • 1
  • Nicholas J. Kenyon
    • 1
  • Timothy E. Albertson
    • 2
  1. 1.Division of Pulmonary and Critical Care Medicine, Department of Medicine, School of MedicineUniversity of California at DavisDavis
  2. 2.Division of Pulmonary and Critical Care Medicine, Department of Medicine, School of MedicineUniversity of California at DavisDavis

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