Congenital and Perinatal Infections

Part of the series Infectious Disease pp 271-288

Mycoplasma and Ureaplasma

  • Ken B. WaitesAffiliated withDivision of Laboratory Medicine, Department of Pathology, University of Alabama at Birmingham

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The concept that Mycoplasma hominis and Ureaplasma spp could be important pathogens that may affect pregnancy outcomes and the health of neonates was first given serious consideration in the 1960s and early 1970s when reports of postpartum endometritis with septicemia, chorioamnionitis, and low birth weight caused by these organisms began to appear and a treatment trial of pregnant women given tetracycline showed a significant beneficial effect on birth weight for their infants (14). Since those days, a great many more case reports have been described, and numerous clinical studies have been performed in an attempt to clarify what roles, if any, these organisms play as agents responsible for invasive infections in neonates, premature labor, spontaneous abortion, stillbirth, and chronic lung disease of prematurity.