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Sydenham’s Chorea, PANDAS, and Other Poststreptococcal Neurological Disorders

  • Roser Pons
Part of the Current Clinical Neurology book series (CCNEU)

Abstract

A 12-year-old boy developed hyperthyroidism secondary to Grave’s disease, which was successfully treated with I-131 treatment. Several months later, pharyngeal infection with group A β-hemolytic Streptococcus was documented by throat culture and subsequent rise in antistreptolysin O titer. He was treated with oral antibiotics, and 2 weeks later developed insidious, progressive chorea, incoordination with right hemibody, and imbalance. Examination revealed moderate chorea affecting the eyes, arms, and legs, incoordination of fine hand movements, motor impersistence on hand grip and tongue protrusion, and near inability to walk. He was treated with valproic acid, and his symptoms resolved within 3 weeks.

Keywords

Attention Deficit Hyperactivity Disorder Valproic Acid Rheumatic Fever Streptococcal Infection Streptococcal Pharyngitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Humana Press Inc. 2005

Authors and Affiliations

  • Roser Pons
    • 1
  1. 1.Department of NeurologyColumbia University Medical CenterNew York

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