Abstract
Completion of the human genome sequence has opened up an enormous opportunity to researchers all over the world. The Human Genome Project, which includes the expressed sequence tags (ESTs) database and the genome sequence database, provides a huge source of data that can be used to study and identify molecular targets for a wide range of diseases, including cancer. Major efforts must now be devoted to develop strategies by which these databases will be mined efficiently to identify the hidden therapeutic treasures. We have utilized the EST and genome databases, different bioinformatics tools, and several experimental methods to identify tissue-specific genes for prostate and breast cancer. The genes identified can be used as novel targets for the diagnosis and treatment of prostate and breast cancer.
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© 2005 Humana Press Inc., Totowa, NJ
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Bera, T.K., Egland, K.A., Lee, B.K., Pastan, I. (2005). Identification of Novel Cancer Target Antigens Utilizing EST and Genome Sequence Databases. In: LaRochelle, W.J., Shimkets, R.A. (eds) The Oncogenomics Handbook. Cancer Drug Discovery and Development. Humana Press. https://doi.org/10.1385/1-59259-893-5:31
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DOI: https://doi.org/10.1385/1-59259-893-5:31
Publisher Name: Humana Press
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