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Bone Allograft Transplantation

Theory and Practice

  • Chapter
Bone Regeneration and Repair

Abstract

An amazing change has occurred in the last 30 yr in our ability to care for children and adults with bone sarcomas. Because of better imaging technology and vast improvements in our systems for treating sarcoma with chemotherapy, we no longer use amputations as our first line of care and now perform limb-sparing surgery for most of our patients. The success of metallic implants is very attractive, and many centers use these technologies (1–14) in the treatment of high-grade tumors involving a joint, but in addition there is a long history in orthopedics of the use of allograft implants (15–42). The latter system is intriguing in many ways and may in fact outlive the metallic implants over time. The aim of this chapter is to review the history of allografting, describe the current state of knowledge, present our series of over 1000 cases and their complications, and then try to establish some rules and approaches to alloimplants of the future.

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Authors and Affiliations

  1. Orthopedic Oncology Service, Massachusetts General Hospital and Children’s Hospital, Harvard Medical School, Boston, MA

    Henry J. Mankin MD, Francis J. Hornicek MD,PhD & William W. Tomford MD

  2. Beth Israel Deaconess Hospital and Othopaedic Oncology Service, Children’s Hospital, Boston, MA

    Mark C. Gebhardt MD (Chief of Orthopaedics)

Authors
  1. Henry J. Mankin MD
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  2. Francis J. Hornicek MD,PhD
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  3. William W. Tomford MD
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  4. Mark C. Gebhardt MD
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Editor information

Editors and Affiliations

  1. Department of Orthopaedic Surgery David Geffen School of Medicine, University of California, Los Angeles, CA

    Jay R. Lieberman MD

  2. Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT

    Gary E. Friedlaender MD

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© 2005 Humana Press Inc., Totowa, NJ

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Mankin, H.J., Hornicek, F.J., Tomford, W.W., Gebhardt, M.C. (2005). Bone Allograft Transplantation. In: Lieberman, J.R., Friedlaender, G.E. (eds) Bone Regeneration and Repair. Humana Press. https://doi.org/10.1385/1-59259-863-3:241

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  • DOI: https://doi.org/10.1385/1-59259-863-3:241

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-847-9

  • Online ISBN: 978-1-59259-863-2

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