Abstract
Apraxia is a term used to denote a wide spectrum of higher-order motor disorders that result from acquired brain disease affecting the performance of skilled and/or learned movements with or without preservation of the ability to perform the same movement outside the clinical setting in the appropriate situation or environment. The disturbance of purposive movements cannot be termed apraxia, however, if the patient suffers from any elementary motor or sensory deficit (i.e., paresis, dystonia, ataxia) that could fully explain the abnormal motor behavior or if it results from a language comprehension disorder or from dementia (1,2). Nevertheless, praxic errors are at present much better defined clinically and kinematically and may be distinguished from other nonapractic motor behaviors (3, 4). Praxic disturbances may affect specific parts of the body (i.e., limb apraxia, facial apraxia) and may involve both sides of the body (i.e., ideational [IA] and ideomotor apraxias [IMA]), preferentially one side (i.e., limb-kinetic apraxia [LKA]), or alternatively, interlimb coordination, as in the case of gait apraxia.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Roy EA, Square PA. Common considerations in the study of limb, verbal, and oral apraxia. In Roy EA, ed. Neuropsychological Studies of Apraxia and Related Disorders. Amsterdam: North-Holland, 1985:111–161.
De Renzi E. Apraxia. In Boller F, Grafman J, eds. Handbook of Neuropsychology. Amsterdam: Elsevier Science, 1989:245–263.
Rothi LJ, Heilman KM, eds. Apraxia: The Neuropsychology of Action. East Sussex: Psychology Press, 1997.
Leiguarda R, Marsden CD. Limb apraxias: higher-order disorders of sensorimotor integration [Review]. Brain 2000;123:860–879.
Freund HJ. The apraxias. In: Asbury Ak, McKhann GM, McDonald WJ, eds. Diseases of the Nervous System. Clinical Neurobiology, 2nd ed. Philadelphia: Saunders, 1992:751–767.
Rebeiz JJ, Kolodny EH, Richardson EP. Corticodentatonigral degeneration with neuronal achromasia. Arch Neurol 1968;18:20–33.
Riley DE, Lang AE, Lewis A, et al. Corticobasal ganglionic degeneration. Neurology 1990;40: 1203–1212.
Gibb WR, Luthert PJ, Marsden CD. Corticobasal degeneration. Brain 1989;112:1171–1192.
Rinne J, Lee M, Thompson P, Marsden CD. Corticobasal degeneration: A clinical study of 36 cases. Brain 1994;117:1183–1196.
Leiguarda R, Lees AJ, Merello M, Starkstein S, Marsden CD. The nature of apraxia in corticobasal degeneration. J Neurol Neurosurg Psychiatry 1994;57:455–459.
Kampoliti K, Goetz CG, Boeve BF, et al. Clinical presentation and pharmacological therapy in corticobasal degeneration. Arch Neurol 1998;55:957–961.
Litvan I, Agid Y, Goetz C, et al. Accuracy of the clinical diagnosis of corticobasal degeneration: a clinicopathologic study. Neurology 1997;48:119–125.
Leiguarda R, Pramstaller P, Merello M, Starkstein S, Lees AJ, Marsden CD. Apraxia in Parkinson’s disease, progressive supranuclear palsy, multiple system atrophy, and neuroleptic induced parkinsonism. Brain 1997;120:75–90.
Hamilton JM, Haaland KY, Adair JC, Brandt J. Ideomotor limb apraxia in Huntington’s disease: implications for corticostriatal involvement. Neuropsychologia 2003;41:614–621.
Monza D, Soliveri P, Radice D, et al. Cognitive dysfunction and impaired organization of complex mobility in degenerative parkinsonian syndromes. Arch Neurol 1998;55:372–378.
Buxbaum LJ, Giovannetti, Libon D. The role of the dynamic body schema in praxis: evidence from primary progressive apraxia. Brain Cog 2000;44:166–191.
Liepmann H. Apraxia. Ergeb Gesamten Medizin 1920;1:516–543.
Clark MA, Merians AS, Kothari A, et al. Spatial planning deficits in limb apraxia. Brain 1994;117: 1093–1106.
Poizner H, Clark MA, Merians AS, Macauley B, Gonzalez Rothi LJ, Heilman KM. Joint coordination deficits in limb apraxia. Brain 1995;118:227–242.
Leiguarda R, Starkstein S. Apraxia in the syndromes of Pick Complex. In Kertesz A, Muñoz DG, eds. Pick’s Disease and Pick Complex. New York: Wiley-Liss, 1998:129–143.
Leiguarda R, Merello M, Balej J. Apraxia in corticobasal degeneration. In: Litvan I, Goetz CG, Lang A, eds. Corticobasal Degeneration and Related Disorders. Advances in Neurology, vol. 82. Philadelphia: Lippincott Williams & Wilkins, 2000:103–121.
Leiguarda R, Merello M, Balej J, Starkstein S, Nogués M, Marsden C. D. Disruption of spatial organization and interjoint coordination in Parkinson’s disease, progressive supranuclear palsy and multiple system atrophy. Mov Disord 2000;15:627–640.
Haaland KY, Harrington DL, Knight RT. Spatial deficits in ideomotor limb apraxia. A kinematic analysis of aiming movements. Brain 1999;122:1169–1182.
Caselli RJ, Stelmach GE, Caviness JV, et al. A kinematic study of progressive apraxia with and without dementia. Mov Disord 1999;14:276–287.
Leiguarda R, Merello M, Nouzeilles MI, Balej J, Rivero A, Nogués M. Limb-kinetic apraxia in corticobasal degeneration: clinical and kinematic features. Mov Disord 2003;18(1):49–59.
Haaland KY, Flaherty D. The different types of limb apraxia errors made by patients with left vs. right hemisphere damage. Brain Cog 1984;3:370–384.
Rapcsak SZ, Ochipa C, Beeson PM, Rubens A. Apraxia and the right hemisphere. Brain Cog 1993;23: 181–202.
Rushworth MFS, Nixon PD, Wade DT, Renowden S, Passingham RE. The left hemisphere and the selection of learned actions. Neuropsychologia 1998;36:11–24.
Rushworth MFS, Krams M, Passingham RE. The attentional role of the left parietal cortex: the distinct lateralization and localization of motor attention in the human brain. J Cogn Neurosci 2001;13(5): 698–710.
Ochipa C, Rothi LJG, Heilman KM. Conceptual apraxia in Alzheimer’s disease. Brain 1992;115: 1061–1071.
De Renzi E, Lucchelli F. Ideational apraxia. Brain 1988;113:1173–1188.
Heilman KM, Maher LH, Greenwald L, Rothi LJ. Conceptual apraxia from lateralized lesions. Neurology 1997;49: 457–464.
Hodges JR, Spatt J, Patterson K. “What” and “how”: Evidence for the dissociation of object knowledge and mechanical problem-solving skills in the human brain. Proc Natl Acad Sci USA 1999;96: 9444–9448.
Hodges J, Bozeat S, Lambon Ralph M, Patterson K, Spatt J. The role of conceptual knowledge in object use evidence from semantic dementia. Brain 2000;123:1913–1925.
Pramstaller PP, Marsden CD. The basal ganglia and apraxia [Review]. Brain 1996;119:319–340.
Leiguarda R. Limb-apraxia: cortical or subcortical. Neuroimage 2001;14:S137–S141.
Haaland KY, Harington DL, Knight RT. Neural representations of skilled movement. Brain 2000;123: 2306–2313.
Ochipa C, Rothi LJ, Heilman KM. Conduction apraxia. J Neurol Neurosurg Psychiatry 1994;57: 1241–1244.
Goldenberg G, Hagmann S. The meaning of meaningless gestures: a study of visuo-imitative apraxia. Neuropsychologia 1997;35:333–341.
Spatt J, Bak T, Bozeat S, Patterson K, Hodges JR. Apraxia, mechanical problem solving and semantic knowledge. Contribution to object usage in corticobasal degeneration. J Neurol 2002;249:601–608.
Goldenberg G, Hagmann S. Tool use and mechanical problem solving in apraxia. Neuropsychologia 1998; 36:581–589.
Grèzes J, Costes N, Decety J. The effects of learning and intention on the neural network involved in the perception of meaningless actions. Brain 1999;122:1875–1887.
Hermsdörfer J, Goldenberg G, Wachsmuth C, et al. Cortical correlates of gesture processing: clues to the cerebral mechanisms underlying apraxia during the imitation of meaningless gestures. Neuroimage 2001;14: 149–161.
Goldenberg G, Straus S. Hemisphere asymmetries for imitation of novel gestures. Neurology 2002;59: 893–897.
Alexander GE, DeLong MR, Strick PL. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Ann Rev Neurosci 1986;9:357–381.
Yeterian EH, Pandya DN. Striatal connections of the parietal association cortices in rhesus monkeys. J Comp Neurol 1993;332:175–197.
Kleist K. Kortikate (innervatorische) Apraxie. J Psychiat Neurol 1907;25:46–112.
Kleist K. Gehirnpathologische und lokalisatorische Ergebnisse: das Stirnhirn im engeren Sinne und seine Störungen. Zeitschrift ges Neurologie und Psychiatrie 1931;131:442–448.
Denes G, Mantovan MC, Gallana A, Cappelletti JV. Limb-kinetic apraxia. Mov Disord 1998;13: 468–476.
Blasi V, Labruna L, Soricelli A, Carlomagno S. Limb-kinetic apraxia: a neuropsychological description. Neurocase 1999;5:201–211.
Raade AS, Rothi LJG, Helman KM. The relationship between buccofacial and limb apraxia. Brain Cog 1991; 16:130–146.
Bizzozero I, Costato D, Della Sala S, Papagno C, Spinnler H, Venneri A. Upper and lower face apraxia: role of the right hemisphere. Brain 2000;123:2213–2230.
Boghen D. Apraxia of lid opening: a review. Neurology 1997; 48:1491–1494.
Tozlovanu V, Forget R, Iancu A. Boghen D. Prolonged orbicularis oculi activity. A major factor in apraxia of lid opening. Neurology 2001;57:1013–1018.
Kase CS, Troncoso JF, Court JE, Tapia JF, Mohr JP. Global spatial disorientation: clinico-pathologic correlations. J Neurol Sci 1977;34:267–278.
Okuda B, Tanaka H, Kawabata K, Tachibana H, Sugita M. Truncal and limb apraxia in corticobasal degeneration. Mov Disord 2001;16:760–762.
Jacobs DH, Adair JC, Macauley BL, Gold M, Gonzalez Rothi LJ, Heilman KM. Apraxia in corticobasal degeneration. Brain Cogn 1999;40:336–354.
Pillon B, Blin J, Vadailhet M, et al. The neuropsychological pattern of corticobasal degeneration: comparison with supranuclear palsy and Alzheimer’s disease: Neurology 1995;45:1477–1483.
Blondel A, Eustache F, Schaeffer S, Maire R, Lechvalier B, Sayette V. Etudie clinique et cognitive de l’apraxie dans l’atrophie cortico-basale. Rev Neurol (Paris) 1997;153:737–747.
Peigneux P, Van Der Linden M, Andres-Benito P, Sadzot B, Franck G, Salmon E. Exploration neuropsychologique et par imagerie fonctionnalle cérébrale d’une apraxia visuo-imitative. Rev Neurol (Paris) 2000;156(5):459–472.
Graham NL, Zenan A, Young AW, Patterson K, Hodges JR. Dyspraxia in a patient with corticobasal degeneration: the role of visual and tactile inputs to action. J Neurol Neurosurg Psychiatry 1999;67:334–344.
Pharr V, Utte B, Stark M, Litvan I, Fantie B, Grafman J. Comparision of apraxia in corticobasal degeneration and progressive supranuclear palsy. Neurology 2001;56:957–963.
Spatt J, Bak T, Bozeat S, Patterson K, Hodges JR. Apraxia, mechanical problem solving and semantic knowledge. Contributions to object usage in corticobasal degeneration. J Neurol 2002;249:601–608.
Kertesz A, Martínez-Lange P, Davidson W, Muñoz DG. The corticobasal degeneration syndrome overlaps progressive aphasia and frontotemporal dementia. Neurology 2000;14:1368–1375.
Okuda B, Tachibana H, Kawabata K, Takeda M, Sugita M. Slowly progressive limb-kinetic apraxia with a decrease in unilateral cerebral blood flow. Acta Neurol Scand 1992;86:76–81.
Ozsancak C, Auzou P, Hannequin D. Dysarthria and orofacial apraxia in corticobasal degeneration. Mov Disord 2000;15:905–910.
Dickson DW, Liu WK, Reding HK, Yen SH. Neuropathologic and molecular considerations, in corticobasal degeneration and related disorders. In: Litvan I, Goetz CG, Lang AE, eds. Advances in Neurology, vol. 82. Philadelphia: Lippincott Williams & Wilkins, 2000:9–28.
Brooks DJ. Functional imaging studies in corticobasal degeneration, in corticobasal degeneration and related disorders. In: Litvan I, Goetz CG, Lang AE, eds. Advances in Neurology, vol. 82. Philadepphia: Lippincott Williams & Wilkins, 2000:209–216.
Litvan I, Agid I, Calue D, et al. Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome): report of the NINDS-SPSP international workshop. Neurology 1996;47: 1–9.
Nath U, Ben-Shlomo Y, Thomson RG, Lees AJ, Buru DJ. Clinical features and natural history of progressive supranuclear palsy. Neurology 2003;60:910–916.
McKeith IG, Galasco D, Kosaba K. Consensus guidelines for the clinical and pathological diagnosis of dementia with lewy bodies (DLB): report of the consortium on DLB international work shop. Neurology 1996;47: 113–124.
Daniel SE, de Bruin V, Lees AJ. The clinical and pathological spectrum of Steele-Richardson-Olszewski syndrome (progressive supranuclear palsy): a reappraises [Review]. Brain 1995;118:759–770.
Abeleyra C, Marello, M, Manes F, Leiguarda R. Defective imitation of limbgestures in Lewy body dementia, in preparation.
Bergeron C, Pollamen MS, Weyer L, Lang AE. Cortical degeneration in progressive supranuclear palsy. A comparison with cortical-basal ganglionic degeneration. J Neuropathol Exp Neurol 1997;56:726–734.
Rinne J, Portin R, Routtinen H, et al. Cognitive impairment and the brain dopaminergic system in Parkinson disease. Arch Neurol 2000;57:470–475.
Hu MTM, Taylor-Robinson SD, Ray Chaudhuri K, et. al. Evidence for cortical dysfunction in clinically non-demented patients with Parkinson’s disease: a proton MR spectroscopy study. J Neurol Neurosurg Psychiatry 1999;67:20–26.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2005 Humana Press Inc., Totowa, NJ
About this chapter
Cite this chapter
Leiguarda, R. (2005). Role of Praxis in Diagnosis and Assessment. In: Litvan, I. (eds) Atypical Parkinsonian Disorders. Current Clinical Neurology. Humana Press. https://doi.org/10.1385/1-59259-834-X:197
Download citation
DOI: https://doi.org/10.1385/1-59259-834-X:197
Publisher Name: Humana Press
Print ISBN: 978-1-58829-331-2
Online ISBN: 978-1-59259-834-2
eBook Packages: MedicineMedicine (R0)