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Multidetector-Row CT vs Intravascular Ultrasound for Coronary Plaque Characterization

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CT of the Heart

Part of the book series: Contemporary Cardiology ((CONCARD))

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Abstract

Coronary artery disease (CAD) constitutes a major clinically relevant disease in the Western industrialized world, causing 600,000 deaths annually (1). The underlying pathophysiological mechanism seems to be coronary plaque disruption, subsequent thrombosis, and acute myocardial infarction. Fifty percent of afflicted patients experience this potentially life-threatening condition without experiencing prior symptoms (2). Therefore, direct visualization of epicardial coronary arteries is necessary to assess the focal severity and clinical relevance of the vessel wall alterations. The visualization of plaque has two different clinical focal points. On the one hand, obstructive coronary artery disease causing chronic ischemia to the vessel-dependent myocardial tissue needs to be assessed to determine an adequate revascularization strategy (condition of stable angina pectoris). On the other hand, precursors of the already mentioned unheralded plaque rupture causing unstable angina, myocardial infarction, or sudden death should be assessed to take preventive measures to avoid these acute coronary syndromes.

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Author information

Authors and Affiliations

  1. Department of Radiology, University of Tübingen, Tübingen, Germany

    Axel Kuettner MD

Authors
  1. Axel Kuettner MD
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Editor information

Editors and Affiliations

  1. Department of Radiology, Medical University of South Carolina, Charleston, SC

    U. Joseph Schoepf MD

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© 2005 Humana Press, Inc., Totowa, NJ

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Kuettner, A. (2005). Multidetector-Row CT vs Intravascular Ultrasound for Coronary Plaque Characterization. In: Schoepf, U.J. (eds) CT of the Heart. Contemporary Cardiology. Humana Press. https://doi.org/10.1385/1-59259-818-8:381

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  • DOI: https://doi.org/10.1385/1-59259-818-8:381

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-303-9

  • Online ISBN: 978-1-59259-818-2

  • eBook Packages: MedicineMedicine (R0)

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