Dengue Virus

  • Enid J. García-Rivera
  • José G. Rigau-Pérez
Part of the Infectious Disease book series (ID)

Abstract

Dengue is the most frequently reported human viral disease transmitted by arthropod vectors. The disease is endemic in most tropical and subtropical areas; over half of the world’s population lives in locations that are at risk for transmission (Fig. 1). Worldwide, there are an estimated 50–100 million cases of dengue and 250,000–500,000 cases of dengue hemorrhagic fever (DHF) annually. During the last few decades, dengue epidemics have been reported in countries that had not previously been considered endemic (1). This chapter provides a brief review of the clinical and laboratory features of dengue and DHF, a detailed discussion of dengue infection during pregnancy, and specific characteristics of dengue during the perinatal period.

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References

  1. 1.
    Gubler DJ. Dengue and dengue hemorrhagic fever: its history and resurgence as a global public health problem. In: Gubler DJ, Kuno G, eds. Dengue and Dengue Hemorrhagic Fever. Wallingford, UK: CAB International, 1997:1–22.Google Scholar
  2. 2.
    Rigau-Pérez JG, Clark GG, Gubler DJ, Reiter P, Sanders EJ, Vorndam AV. Dengue and dengue hemorrhagic fever. Lancet 1998:352:971–977.PubMedCrossRefGoogle Scholar
  3. 3.
    Gubler DJ, Suharyono W, Sumarmo, Wulur H, Jahja E, Sulianti-Saroso J. Virological surveillance for dengue hemorrhagic fever in Indonesia using the mosquito inoculation technique. Bull WHO 1979;57:932–936.Google Scholar
  4. 4.
    Siler JF, Hall MW, Hitchens AP. Dengue: its history, epidemiology, mechanism of transmission, etiology, clinical manifestations, immunity, and prevention. Philippine J Sci 1926;29:1–304.Google Scholar
  5. 5.
    George R, Lum LCS. Clinical spectrum of infection. In: Gubler DJ, Kuno G, eds. Dengue and Dengue Hemorrhagic Fever. Wallingford, UK: CAB International, 1997:89–113.Google Scholar
  6. 6.
    Cobra C, Rigau-Pérez J, Kuno G, Vorndam V. Symptoms of dengue fever in relation to host immunologic response and virus serotype, Puerto Rico, 1990–1991. Am J Epidemiol 1995;142:1204–1211.PubMedGoogle Scholar
  7. 7.
    Dietz V, Gubler DJ, Ortiz S, et al. The 1986 dengue and dengue hemorrhagic fever epidemic in Puerto Rico: epidemiologic and clinical observations. P R Health Sci J 1996;15:201–210.PubMedGoogle Scholar
  8. 8.
    Wintrobe MM. Clinical Hematology. Philadelphia: Lea and Febiger, 1961:299.Google Scholar
  9. 9.
    Gubler DJ, Trent DW. Emergence of epidemic dengue/dengue hemorrhagic fever as a public health problem in the Americas. Infect Agents Dis 1993;2:383–393.PubMedGoogle Scholar
  10. 10.
    Halstead SB. Pathogenesis of dengue: challenges to molecular biology. Science 1988;239:476–481.PubMedCrossRefGoogle Scholar
  11. 11.
    Halstead SB. Epidemiology of dengue and dengue hemorrhagic fever. In: Gubler DJ, Kuno G, eds. Dengue and dengue hemorrhagic fever. Wallingford, UK: CAB International, 1997:23–44.Google Scholar
  12. 12.
    Kliks SC, Nimmanitya S, Nisalak A, Burke D. Evidence that maternal antibodies are important in the development of dengue hemorrhagic fever in infants. Am J Trop Med Hyg 1988;38:411–419.PubMedGoogle Scholar
  13. 13.
    Figueiredo LT, Carlucci RH, Duarte G. Prospective study with infants whose mother had dengue during pregnancy. Rev Inst Med Trop Sao Paulo 1994;136:417–421.Google Scholar
  14. 14.
    Carey D, Myers R, Wilson E, Manoharan A. Transplacentally-acquired group-B HI antibody and dengue infection among infants in Vellore, South India. Ind J Med Res 1968;56:1468–1477.Google Scholar
  15. 15.
    Cantelar FN, Molina AL. Dengue: estudio clinicoserológico en madres y recién nacidos. Rev Cubana Med Trop 1981;33:96–105.Google Scholar
  16. 16.
    Molina AL, Cantelar FN, GarcÍa-Santana C. Dengue: respuesta serológica e inmunológica en recién nacidos. Rev Cub Hig Epid 1981;19:346–350.Google Scholar
  17. 17.
    Martínez E, Guzmán M, Valdés M, Soler M, Kourí G. Dengue fever and hemorrhagic dengue in infants with a primary infection. Rev Cubana Med Trop 1993;45:97–101.PubMedGoogle Scholar
  18. 18.
    Halstead S, Nimmammitya S, Margiotta M. Dengue and chinkungunya virus infection in man in Thailand, 1962–1964. Am J Trop Med Hyg 1969;18:972–983.PubMedGoogle Scholar
  19. 19.
    Tassniyom S, Vasanawathana S, Chirawatkul A, Rojanasuphot S. Failure of high dose methylprednisolone in established dengue shock syndrome: a placebo-controlled, double blind study. Pediatrics 1993;92:111–115.PubMedGoogle Scholar
  20. 20.
    Ventura A, Ehrenkranz J, Rosenthal D. Placental passage of antibodies to dengue virus in persons living in a region of hyperendemic dengue virus infection. J Infect Dis 1975;131(Suppl):S62–S68.PubMedGoogle Scholar
  21. 21.
    Moreau JP, Rosen L, Saugrain J, Lagraulet J. An epidemic of dengue on Tahiti associated with hemorrhagic manifestations. Am J Trop Med Hyg 1973;22:237–241.PubMedGoogle Scholar
  22. 22.
    Taechakraichana N, Limpaphayom K. Dengue hemorrhagic fever in pregnancy. Chula Med J 1989;33:213–218.Google Scholar
  23. 23.
    Thaithumyanon P, Thisyakorn U, Deerojnawong J, Innis DL. Dengue infection complicated by severe hemorrhage and vertical transmission in a parturient woman. Clin Infect Dis 1994;18:248–249.PubMedGoogle Scholar
  24. 24.
    Chye JK, Lim CT, Kwee BN, Lim JMH, George R, Lam SK. Vertical transmission of dengue. Clin Infect Dis 1997;25:1374–1377.PubMedGoogle Scholar
  25. 25.
    Bunyavejchevin S, Tanawattanacharoen S, Taechakraichana N, Thisyakorn U, Tannirandirn Y, Limpaphayom K. Dengue hemorrhagic fever during pregnancy: antepartum, intrapartum and postpartum management. J Obstet Gynaecol Res 1997;23:445–448.PubMedGoogle Scholar
  26. 26.
    Carles G, Peiffer H, Talarmin A. Effects of dengue fever during pregnancy in French Guiana. Clin Infect Dis 1999;28:637–649.PubMedGoogle Scholar
  27. 27.
    Boussemart T, Babe P, Sibille G, Neyret C, Berchel C. Prenatal transmission of dengue: two new cases. J Perinatol 2001;21:255–257.PubMedCrossRefGoogle Scholar
  28. 28.
    Kerdpanich A, Watanaveradej V, Samakoses R, et al. Perinatal dengue infection. Southeast Asian J Trop Med Public Health 2001;32:488–493.PubMedGoogle Scholar
  29. 29.
    Chotigeat U, Kalayanarooj S, Nisalak A. Vertical transmission of dengue infection in Thai infants: two cases reports. J Med Assoc Thai 2003;86(Suppl 3):S628–S632.PubMedGoogle Scholar
  30. 30.
    Watanaveeradej V, Kerdpanich A, Chulyamitporn T, Nisalak A, Endy P. Perinatal transmission of dengue viral infection. Am J Trop Med Hyg 2000;62(3 Suppl):S342.Google Scholar
  31. 31.
    Poli L, Chungue E, Soulignac O, Gestas P, Kuo P, Papouin-Rauzy M. Dengue maternofoetale. Bull Soc Path Exot 1991;84:513–521.Google Scholar
  32. 32.
    Gubler DJ, Suharyono W, Tan R, Abidin M, Sie A. Viremia in patients with naturally acquired dengue infection. Bull WHO 1981;59:623–630.PubMedGoogle Scholar
  33. 33.
    Vaughn DW, Green S, Kalayanarooj S, et al. Dengue in the early febrile phase: viremia and antibody responses. J Infect Dis 1997;176:322–330.PubMedCrossRefGoogle Scholar
  34. 34.
    Vorndam AV, Kuno G. Laboratory diagnosis of dengue virus infections. In: Gubler DJ, Kuno G, eds. Dengue and dengue hemorrhagic fever. Wallingford, UK: CAB International, 1997:313–333.Google Scholar
  35. 35.
    Gubler DJ, Sather GE. Laboratory diagnosis of dengue and dengue hemorrhagic fever. In: Fonseca da Cunha F, ed. Simposio Internacional sobre Febre Amarela e Dengue, 1988. Rio de Janeiro: Fundaçao Oswaldo Cruz/Bio-Manguinhos, 1988:291–322.Google Scholar

Copyright information

© Humana Press Inc., Totowa, NJ 2006

Authors and Affiliations

  • Enid J. García-Rivera
    • 1
  • José G. Rigau-Pérez
    • 2
  1. 1.Dengue BranchCenters for Disease Control and PreventionSan Juan
  2. 2.Epidemiology, Entomology and Prevention Activity, Dengue BranchCenters for Disease Control and PreventionSan Juan

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