Skip to main content

The Construction of a Culture of Standardization at the Institut Pasteur (1885–1900)

  • Chapter
Evaluating and Standardizing Therapeutic Agents, 1890–1950

Part of the book series: Science, Technology and Medicine in Modern History ((STMMH))

  • 86 Accesses

Abstract

The initial wave of conception and production of animal and human vaccines supervised by Louis Pasteur (1822–95), although considered a great achievement in France, suffered from several theoretical, methodological and technical weaknesses that threatened the reproducibility of the results as well as part of the validity of Pasteur’s approach. While these problems were mostly pointed out by German scientists, there were also French critics of Pasteur’s work.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 54.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

Notes

  1. G. Geison, The Private Science of Louis Pasteur, Princeton University Press, Princeton, 1995.

    Google Scholar 

  2. T. D. Brock, Robert Koch: A Life in Medicine and Bacteriology, ASM press, Washington, 1998

    Google Scholar 

  3. A. M. Silverstein, A History of Immunology, Academic Press, San Diego CA, 1989.

    Google Scholar 

  4. C. Gradmann, ‘Maladies expérimentales. Les expériences sur l’animal aux débuts de la bactériologie médicale’, in G. Gachelin (ed.), Les organismes modèles dans la recherche médicale, Presses Universitaires de France, Paris, 2006, pp. 75–94.

    Google Scholar 

  5. P. Weindling, ‘From Medical Research to Clinical Practice: Serum Therapy for Diphtheria in the 1890s’, in J. Pickstone (ed.), Medical Innovations in Historical Perspective, St Martin’s Press, New York, 1992, pp. 72–83.

    Chapter  Google Scholar 

  6. I. Chalmers, ‘Comparing Like with Like: Some Historical Milestones in the Evolution of Methods to Create Unbiased Comparison Groups in Therapeutic Experiments’, British Medical Journal, 1998 317: 1167.

    Article  Google Scholar 

  7. A. Chaillou, and L. Martin, ‘Etude clinique et bactériologique sur la diphtérie. Travail du laboratoire du Dr. Roux’, Annales de l’Institut Pasteur, 1894, 8: 449–78.

    Google Scholar 

  8. C. Debue Barazer, ‘Les implications scientifiques et industrielles du succès de la Stovaïne. Ernest Fourneau (1873–1949) et la chimie des médicaments en France’, Gesnerus 2007 64: 24–53.

    Google Scholar 

  9. J. Carroy and H. Schmidgen, ‘Reaktionsversuche in Leipzig, Paris und Würzburg: Die deutsch-französische Geschichte eines psychologischen Experiments, 1890–1910’, Medizinhistorisches Journal 2004 39: 27–55.

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Copyright information

© 2010 Gabriel Gachelin

About this chapter

Cite this chapter

Gachelin, G. (2010). The Construction of a Culture of Standardization at the Institut Pasteur (1885–1900). In: Gradmann, C., Simon, J. (eds) Evaluating and Standardizing Therapeutic Agents, 1890–1950. Science, Technology and Medicine in Modern History. Palgrave Macmillan, London. https://doi.org/10.1057/9780230285590_5

Download citation

  • DOI: https://doi.org/10.1057/9780230285590_5

  • Publisher Name: Palgrave Macmillan, London

  • Print ISBN: 978-1-349-30087-7

  • Online ISBN: 978-0-230-28559-0

  • eBook Packages: Palgrave History CollectionHistory (R0)

Publish with us

Policies and ethics