Adult Endocrinology

  • Leighton Seal
Part of the Critical and Applied Approaches in Sexuality, Gender and Identity book series (CAASGI)


This chapter considers the endocrine treatment possibilities for non-binary adults. It discusses the various medicines and interventions which are commonly used and also considers the pros and cons of less commonly used interventions. It also explores the sensitivities necessary when working with this patient group so as to establish good rapport, and the best form of multidisciplinary working for endocrinologists and the wider multidisciplinary team. Lastly, it details the possibilities and limitations of current medicine with regard to effecting non-binary physical changes.


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Further Reading

  1. Barrett, J. D. (2007). Transsexual and Other Disorders of Gender Identity: A Practical Guide to Management. Abingdon, UK: Radcliffe.Google Scholar
  2. Hembree, W. C., Cohen-Kettenis, P., Delemarre-van de Waal, H. A., Gooren, L. J., Meyer, W. J., Spack, N. P., et al. (2009). Endocrine Treatment of Transsexual Persons: An Endocrine Society Clinical Practice Guideline. The Journal of Clinical Endocrinology & Metabolism, 94(9), 3132–3154. doi:10.1210/jc.2009-0345.
  3. Melmed, S., & Williams, R. H. (2011). Williams Textbook of Endocrinology (12th ed.). Philadelphia, PA: Elsevier/Saunders.Google Scholar
  4. Seal, L. J. (2015). A Review of the Physical and Metabolic Effects of Cross-Sex Hormonal Therapy in the Treatment of Gender Dysphoria. Annals of Clinical Biochemistry. doi:10.1177/0004563215587763.
  5. Wylie, K., Barrett, J., Besser, M., Bouman, W., Brain, C., Bridgman, M., et al. (2013). Good Practice Guidelines for the Assessment and Treatment of Adults with Gender Dysphoria. Retrieved from

Copyright information

© The Author(s) 2017

Authors and Affiliations

  • Leighton Seal
    • 1
  1. 1.Charing Cross Gender Identity ClinicLondonUK

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