Spontaneous vesicle formation from a one-component solution of a biological surfactant

  • L. Cantu
  • M. Corti
  • M. Musolino
  • P. Salina
Part of the Progress in Colloid & Polymer Science book series (PROGCOLLOID, volume 84)


Spontaneous formation of unilamellar vesicles from a solution of a single surfactant in water at normal pH is reported. The surfactant is the ganglioside GM3, a glucosidic amphiphile of biological origin. The vesicle average diameter sharply changes from 530 Å to 490 Å across the chain melting transition temperature at about 30°C. No hysteresis effects are found and vesicles are extremely stable. The bilayer thickness is surprisingly small, indicating that hydrophobic chains are fully interdigitated.

Key words

Spontaneous vesicles biological surfactants self-aggregation light-scattering 


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Copyright information

© Dr. Dietrich Steinkopff Verlag GmbH & Co. KG 1991

Authors and Affiliations

  • L. Cantu
    • 1
  • M. Corti
    • 1
    • 2
  • M. Musolino
    • 1
  • P. Salina
    • 1
  1. 1.Dipartimento di Chimica e Biochimica MedicaUniversità di MilanoMilanoItaly
  2. 2.Dipartimento die ElettronicaUniversità di PaviaPaviaItaly

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