Abstract
We propose a Bayesian method whereby MAP estimates of functional (PET and SPECT) images may be reconstructed with the aid of prior information derived from registered anatomical (CT and MRI) images of the same slice. Our prior information consists of significant anatomical boundaries that are likely to correspond to discontinuities in an otherwise spatially smooth radionuclide distribution. Our algorithm, like others proposed recently, seeks smooth solutions with occasional discontinuities; the contribution here is the inclusion of a coupling term that influences the creation of discontinuities in the vicinity of the significant anatomical boundaries. Simulations on anatomically derived mathematical phantoms are presented. The reconstructions are greatly improved when the prior information is used.
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© 1991 Springer-Verlag Berlin Heidelberg
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Gindi, G., Lee, M., Rangarajan, A., Zubal, I.G. (1991). Bayesian reconstruction of functional images using registered anatomical images as priors. In: Colchester, A.C.F., Hawkes, D.J. (eds) Information Processing in Medical Imaging. IPMI 1991. Lecture Notes in Computer Science, vol 511. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0033747
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DOI: https://doi.org/10.1007/BFb0033747
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