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Catecholamine receptors

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Book cover Reviews of Physiology, Biochemistry and Pharmacology, Volume 82

Part of the book series: Reviews of Physiology, Biochemistry and Pharmacology ((REVIEWS,volume 82))

Abstract

In the last few years the characterization of catecholamine receptors has developed considerably. The primary biochemical signals occurring subsequent to catecholamine binding are better understood today than a few years ago. Specific ligands can now be used to monitor catecholamine receptors both in vitro and in vivo. This applies especially to the field of β-adrenergic receptors. Even attempts to solubilize and affinity label the β-adrenergic receptor have met with initial success. It is to be expected that within a few years the mechanism of β-receptor activity will be understood more fully and that further progress will be made in the field of α-adrenergic and dopamine receptors.

Dedication. This article is dedicated to my noble teacher Arieh Berger wo died prematurely six years ago at the age of 51.

Arieh Berger established the molecular basis for the understanding of ligand-macro-molecule recognition through his brilliant studies on the mapping of the active sites of proteolytic enzymes. His work should be a source of inspiration to all molecular pharmacologists as it is for us.

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    Alexander Levitzki

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Levitzki, A. (1978). Catecholamine receptors. In: Reviews of Physiology, Biochemistry and Pharmacology, Volume 82. Reviews of Physiology, Biochemistry and Pharmacology, vol 82. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0030496

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