Advertisement

Hemoglobin model — Artificial oxygen carrier composed of porphinatoiron complexes

  • Eishun Tsuchida
  • Hiroyuki Nishide
Conference paper
Part of the Topics in Current Chemistry book series (TOPCURRCHEM, volume 132)

Keywords

Oxygen Carrier Irreversible Oxidation Imidazole Ligand Heme Complex Porphyrin Plane 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

8 References

  1. 1.
    Dickerson, R. E., Geis, I.: The Structure and Action of Proteins, Harper & Row, London 1969Google Scholar
  2. 2.
    Lehninger, A. L.: Biochemistry (2nd Ed.), Worth Pub. New York 1975Google Scholar
  3. 3.
    Perutz, M. F., Muirhead, H., Cox, J. M., Goaman, L. C.: Nature 219, 131 (1968)Google Scholar
  4. 4.
    Wang, J. H.: J. Am. Chem. Soc. 80, 3168 (1958)CrossRefGoogle Scholar
  5. 5.
    Jones, N. L.: Blood Gases and Acid-Base Physiology, Marcel Decker, New York 1980Google Scholar
  6. 6.
    Cohen, I. A., Caughey, W. S.: Biochem. 7, 636 (1968)Google Scholar
  7. 7.
    Hammond, G. S., Wu, C. S.: Chem. Ser. 77, 186 (1968)Google Scholar
  8. 8.
    Kao, O. H., Wang, J. H.: Biochem. 4, 342 (1965)CrossRefGoogle Scholar
  9. 9.
    Jones, R. D., Summerville, D. A., Basolo, F.: Chem. Rev. 79, 139 (1979)CrossRefGoogle Scholar
  10. 10.
    Collman, J. P.: Acc. Chem. Res. 10, 265 (1977)CrossRefGoogle Scholar
  11. 11.
    Traylor, T. G., Traylor, P. S.: Annu. Rev. Biophys. Bioeng. 11, 105 (1982)CrossRefPubMedGoogle Scholar
  12. 12.
    Baldwin, F. E., Huff, J.: Am. Chem. Soc. 95, 5757 (1973)CrossRefPubMedGoogle Scholar
  13. 13.
    Chang, C. K.: ibid. 99, 2819 (1977)CrossRefPubMedGoogle Scholar
  14. 14.
    Traylor, T. G., Campbell, D., Tsuchiya, S.: ibid. 101, 4748 (1979)CrossRefGoogle Scholar
  15. 15.
    Battersby, A. R., Hamilton, A. D.: J. Chem. Soc., Chem. Commun. 1980, 117Google Scholar
  16. 16.
    Momenteau, M., Loock, B.: J. Mol. Catal. 7, 315 (1980)CrossRefGoogle Scholar
  17. 17.
    Collman, J. P., Gagne, R. R., Halbert, T. R., Marchon, J. C.: J. Am. Chem. Soc. 95, 7868 (1973)CrossRefPubMedGoogle Scholar
  18. 18.
    Collman, J. P., Brauman, J. I., Collins, T. J., Pittman, R. B., Sessler, J. L.: ibid. 105, 3038 (1983)CrossRefGoogle Scholar
  19. 19.
    Chang, C. K., Traylor, T. G.: ibid. 95, 8475 (1973)CrossRefGoogle Scholar
  20. 20.
    Collman, J. P., Gagne, R. R., Reed, C. A., Halbert, T. R., Lang, G.: ibid. 97, 1427 (1975)CrossRefPubMedGoogle Scholar
  21. 21.
    Tsuchida, E.: J. Macromol. Sci. A13, 545 (1979)Google Scholar
  22. 22.
    Traylor, T. G.: Acc. Chem. Res. 14, 102 (1981)CrossRefGoogle Scholar
  23. 23.
    Collman, J. P., Hegedus, L. S.: Principles and Applications of Organotransition Metal Chemistry, University Sci. Books, Cal. 1980Google Scholar
  24. 24.
    Baldwin, J. E., Perlmutter, P.: Top. Curr. Chem. 121, 181 (1984)Google Scholar
  25. 25.
    Baldwin, J. E., Cameron, J. H., Crossley, M. J., Dagley, I. J., Klose, T.: J. Chem. Soc., Dalton Trans. 1984, 1739Google Scholar
  26. 26.
    Momenteau, M., Loock, B., Lavalette, D., Tetreau, C., Mispelter, J.: J. Chem. Soc., Chem. Commun. 1983, 962Google Scholar
  27. 27.
    Suslick, K. S., Fox, M. M., Reinert, T. J.: J. Am. Chem. Soc. 106, 4522 (1984)CrossRefGoogle Scholar
  28. 28.
    Battersby, A. R., Bartholomew, S. A., Nitta, T.: J. Chem. Soc., Chem. Commun. 1983, 1291Google Scholar
  29. 29.
    Chang, C. K., Traylor, T. G.: Proc. Nat. Acad. Sci. USA, 70, 2646 (1973)Google Scholar
  30. 30.
    Traylor, T. G., Tsuchiya, S., Campbell, D., Mitchell, M., Koga, N.: J. Am. Chem. Soc. 107, 604 (1985)CrossRefGoogle Scholar
  31. 31.
    Chang, C. K.: ACS Adv. Chem. Ser. 173, 162 (1979)Google Scholar
  32. 32.
    Ward, B., Wang, C. B., Chang, C. K.: J. Am. Chem. Soc. 103, 5236 (1981)CrossRefGoogle Scholar
  33. 33.
    Tsuchida, E., Nishide, H., Takane, M., Yohsioka, H.: J. Bioinorg. Chem. 25, 43 (1985)Google Scholar
  34. 34.
    Tsuchida, E., Wang, S-g., Yuasa, M., Nishide, H.: J. Chem. Soc., Chem. Commun. 1986, 23Google Scholar
  35. 35.
    Wang, S-g., Nishide, H., Tsuchida, E.: Nippon Kagaku Kaishi (J. Chem. Soc. Jpn.) 1985, 182Google Scholar
  36. 36.
    The cooperative parameter n is estimated from Hill's equation [Hill, A. V.: J. Physiol. 40, 190 (1910); Wymen, J.: Adv. Protein Chem. 19, 223 (1964)]. The relationship between the partial pressure of a gaseous molecule and the degree of the binding with n = 1 corresponds to a hyperbolic binding-equilibrium curve, and that for n > 1 is sigmoidal. The binding with n > 1 is understood that the binding sites cooperatively interact with each other and the binding occurs at a stroke (cooperative binding). n Corresponds to the strength of the cooperative interaction between the sites.Google Scholar
  37. 38.
    Eshima, E., Matsushita, Y., Hasegawa, E., Nishide, H., Tsuchida, E.: Polym. Prepr. Jpn. 31, 542 (1982)Google Scholar
  38. 39.
    Eshima, E., Matsushita, Y., Sekine, M., Nishide, H., Tsuchida, E.: Nippon Kagaku Kaishi (J. Chem. Soc. Jpn.) 1983, 214Google Scholar
  39. 40.
    Eshima, E., Nishide, H., Tsuchida, E.: J. Chem. Soc., Chem. Commun. to be submitted; Jpn. Tokyo Koho JP 59-55885 (1984)Google Scholar
  40. 41.
    Leal, O., Andorson, D. L., Bowman, R. G., Basolo, F.: J. Am. Chem. Soc. 97, 5125 (1975)CrossRefGoogle Scholar
  41. 42.
    Tsuchida, E., Honda, K., Hata, S.: Bull. Chem. Soc. Jpn. 49, 868 (1976)Google Scholar
  42. 43.
    Fuhrhop, J. H., Besecke, S., Subramanian, J.: Makromol. Chem. 178, 1621 (1977)CrossRefGoogle Scholar
  43. 44.
    Nishide, H., Shinohara, K., Tsuchida, E.: J. Polymer Sci. Chem. Ed. 19, 1109 (1981)CrossRefGoogle Scholar
  44. 45.
    Nishide, H., Kato, M., Tsuchida, E.: Eur. Polymer J. 17, 579 (1981)CrossRefGoogle Scholar
  45. 46.
    Tsuchida, E., Nishide, H.: Adv. Polymer Sci. 24, 1 (1977)Google Scholar
  46. 47.
    Kaneko, M., Tsuchida, E.: J. Polymer Sci. Rev. 16, 397 (1981)Google Scholar
  47. 48.
    Tsuchida, E., Nishide, H.: ACS Sym. Ser. 212, 49 (1983)Google Scholar
  48. 49.
    Tsuchida, E., Nishide, H., Ohno, H.: J. Inorg. Biochem. 17, 283 (1982)CrossRefGoogle Scholar
  49. 50.
    Nishide, H., Ohno, H., Tsuchida, E.: Makromol. Chem., Rapid Commun. 2, 55 (1981)Google Scholar
  50. 51.
    Tsuchida, E., Nishide, H., Yokoyama, H.: J. Chem. Soc., Dalton Trans. 1984, 2383 (1984)Google Scholar
  51. 52.
    Uotani, N., Hasegawa, E., Nishide, H., Tsuchida, E.: J. Inorg. Biochem. 22, 85 (1984)CrossRefPubMedGoogle Scholar
  52. 53.
    Tsuchida, E., Nishide, H., Yokoyama, H., Inoue, H.: Polymer J. 16, 325 (1984)Google Scholar
  53. 54.
    Nishide, H., Sekine, M., Tsuchida, E.: ibid. 14, 629 (1982)Google Scholar
  54. 55.
    Tsuchida, E., Nishide, H.: Makromol. Chem., Rapid Commun. 3, 417 (1982)Google Scholar
  55. 56.
    Tsuchida, E., Abe, K.: Adv. Polymer Sci. 45, 1 (1982)Google Scholar
  56. 57.
    Tsuchida, E., Nishide, H., Taguchi, K.: Makromol. Chem., Rapid Commun. 3, 161 (1982)Google Scholar
  57. 58.
    Tsuchida, E., Nishide, H., Sato, Y.: Bull. Chem. Soc., Jpn. 55, 1980 (1982)Google Scholar
  58. 59.
    Tsuchida, E.: J. Pharm. Dyn., 6, 9 (1983)Google Scholar
  59. 60.
    Tsuchida, E., Nishide, H., Sato, Y.: J. Chem. Soc., Chem. Commun. 1982, 556Google Scholar
  60. 61.
    Tsuchida, E., Nishide, H.: J. Chem. Soc., Dalton Trans., to be submittedGoogle Scholar
  61. 62.
    Young, R., Chang, C. K.: J. Am. Chem. Soc. 107, 898 (1985)CrossRefGoogle Scholar
  62. 63.
    Tsuchida, E., Nishide, H., Yokoyama, H., Young, R., Chang, C. K.: Chem. Lett. 1984, 991Google Scholar
  63. 64.
    Nishide, H., Tsuchida, E.: Makromol. Chem. 183, 1883 (1982)CrossRefGoogle Scholar
  64. 65.
    Shigehara, K., Shinohara, K., Sato, Y., Tsuchida, E.: Makromolecules 14, 1153 (1981)CrossRefGoogle Scholar
  65. 66.
    Hasegawa, E., Tsuchida, E.: J. Polymer Sci. Chem. Ed. 15, 3039 (1977)CrossRefGoogle Scholar
  66. 67.
    Tsuchida, E., Hasegawa, E., Kanayama, T.: Macromolecules 11, 947 (1978)CrossRefGoogle Scholar
  67. 68.
    Vasilenko, I. A., Ushakova, I. P., Radyukhin, V. A.: J. Gen. Chem. USSR, 1979, 126Google Scholar
  68. 69.
    Makino, N., Yokoya, M., Sugita, Y.: Biochem. Biophys. Res. Commun. 108, 1010 (1982)CrossRefPubMedGoogle Scholar
  69. 70.
    Hasegawa, E., Matsushita, Y., Eshima, K., Tsuchida, E.: ibid. 104, 793 (1982); 105, 1416 (1982)CrossRefPubMedGoogle Scholar
  70. 71.
    Tsuchida, E., Nishide, H., Yuasa, M., Hasegawa, E., Matsushita, Y.: J. Chem. Soc., Dalton Trans. 1984, 1147Google Scholar
  71. 72.
    Loach, P. A., Kong, J. L. Y.: ACS Symp. Ser. 201, 515 (1982)Google Scholar
  72. 73.
    Fendler, J. H.: Membrane Mimetic Chemistry, John Wiley, New York 1982Google Scholar
  73. 74.
    Eshima, K., Yuasa, M., Nishide, H., Tsuchida, E.: J. Chem. Soc., Chem. Commun. 1985, 130Google Scholar
  74. 75.
    Nishide, H., Maeda, H., Wang, S., Tsuchida, E.: ibid. 1985, 260Google Scholar
  75. 76.
    Matsushita, Y., Hasegawa, E., Eshima, K., Tsuchida, E.: Heterocycles 22, 1403 (1984)Google Scholar
  76. 77.
    Tsuchida, E.: to be publishedGoogle Scholar
  77. 78.
    Matsushita, Y., Hasegawa, E., Eshima, K., Tsuchida, E.: Heterocycles 22, 2547 (1984)Google Scholar
  78. 79.
    Matsushita, Y., Hasegawa, E., Eshima, K., Tsuchida, E.: Chem. Lett. 1983, 1387Google Scholar
  79. 80.
    Tsuchida, E., Hasegawa, E., Matsushita, Y.: Inorg. Chim. Acta 93, 137 (1984)CrossRefGoogle Scholar
  80. 81.
    Tsuchida, E., Nishide, H., Yuasa, M., Hasegawa, E., Matsushita, Y.: J. Chem. Soc., Dalton Trans. 1985, 275Google Scholar
  81. 82.
    Ohno, H., Maeda, Y., Tsuchida, E.: Biochim. Biophys. Acta 642, 27 (1981)PubMedGoogle Scholar
  82. 83.
    Ogata, Y., Nishide, H., Tsuchida, E.: Polym. Prepr. Jpn. 34, 646 (1985)Google Scholar
  83. 84.
    Tsuchida, E., Nishide, H., Sekine, M., Yamagishi, A.: Biochim. Biophys. Acta 734, 274 (1983)PubMedGoogle Scholar
  84. 85.
    Liposomes undergo distinct structural changes at a certain temperature, i.e. the phase transition temperature (Tc), when heated or cooled. These changes do not affect the gross structural features of liposomes, i.e. they remain as roughly spherical closed smectic mesophases of the phospholipid bilayer, and correspond to the orientation of the alkyl chains of the lipid. Below Tc, lipids in the bilayers are in highly ordered gel states, with their alkyl chains in all-trans conformations. Above Tc lipids become liquid crystal states as the consequence of gauche rotations and kink formations. For example, the Tc values of EYL, and DPPC liposomes are −15 to −7, 23.5 and 41 °C, respectively (Ansell, G. B., Dmason, R. M., Hamthorne, J. N.: Form and Function of Phospholipid, Elsevier, Amsterdam 1973).Google Scholar
  85. 86.
    Ringsdorf, H., Gros, L., Schupp, H.: Angew. Chem., Int. Ed. Eng. 20, 305 (1981)Google Scholar
  86. 87.
    Hupfer, B., Ringsdorf, H., Schupp, H.: Makromol. Chem. 182, 247 (1981)CrossRefGoogle Scholar
  87. 88.
    Hasegawa, E., Matsushita, Y., Eshima, K., Nishide, H., Tsuchida, E.: Makromol. Chem., Rapid Commun. 5, 779 (1984)Google Scholar
  88. 89.
    Tsuchida, E., Hasegawa, E., Matsushita, Y., Eshima, K., Yuasa, M., Nishide, H.: Chem. Lett. 1985, 1650Google Scholar
  89. 90.
    Tsuchida, E.: to be publishedGoogle Scholar
  90. 91.
    Yuasa, M., Ogata, Y., Nishide, H., Tsuchida, H., Nozaki, T.: Chem. Lett. 1984, 1889Google Scholar
  91. 92.
    Tsuchida, E., Nishide, H., Yuasa, M.: J. Chem. Soc., Chem. Commun. 1984, 96Google Scholar
  92. 93.
    Tsuchida, E., Yuasa, M., Nishide, H.: J. Chem. Soc., Dalton Trans. 1985, 65Google Scholar
  93. 94.
    Antonini, E., Brunoi, M.: Hemoglobin and Myoglobin in their Reactions with Ligands, North-Holland Pub., Amsterdam 1971Google Scholar
  94. 95.
    Roughton, F. J. W.: Proc. R. Soc. London 111, 1 (1932)Google Scholar
  95. 96.
    Tsuchida, E., Nishide, H., Yuasa, M., Sekine, M.: Bull. Chem. Soc. Jpn. 57, 776 (1984)Google Scholar
  96. 97.
    Yuasa, M., Nishide, H., Tsuchida, E.: J. Pharm. Dyn. 8, 17 (1985)Google Scholar
  97. 98.
    Tsuchida, E.: to be publishedGoogle Scholar
  98. 99.
    Tsuchida, E., Nishide, H., Yuasa, M.: Biochim. Biophys. Acta., to be submittedGoogle Scholar
  99. 100.
    Seki, N., Ohno, H., Tsuchida, E., Sasakawa, S.: Bull. Chem. Soc. Jpn. 57, 2863 (1984)Google Scholar
  100. 101.
    Ohno, H., Seki, N., Tsuchida, E.: Makromol. Chem. 185, 329 (1984)CrossRefGoogle Scholar
  101. 102.
    Tsuchida, E.: to be publishedGoogle Scholar
  102. 103.
    Tam, S., Blumenstein, J., Wong, J. T.: Can. J. Biochem. 56, 981 (1978)PubMedGoogle Scholar
  103. 104.
    Friedman, H. I., De Venuto, F., Schwavtz, B. D., Nemeth, T. J.: Surgery Gynecology Obstetrics, 159, 429 (1984)Google Scholar
  104. 105.
    Chang, T. M. S.: Artificial Cells, Medical Inform. Ser., Montreal 1976Google Scholar
  105. 106.
    Djorjevich, L., Miller, I. F.: Exp. Hemat. 8, 584 (1980)PubMedGoogle Scholar
  106. 107.
    Chem. Eng. News, May 3, 31 (1982)Google Scholar
  107. 108.
    Chem. Eng. News, Jan. 14, 42 (1985)Google Scholar
  108. 109.
    Tsuchida, E., Nishide, H.: Makromol. Chem., Rapid Commun. 3, 693 (1982)Google Scholar
  109. 110.
    Martell, A. E., Calvin, M.: Chemistry of the Metal Chelate Compounds, Printice-Hall, Engelwood 1952Google Scholar
  110. 111.
    Kurimura, Y., Tsuchida, E.: Makromol. Chem. 183, 2889 (1982)CrossRefGoogle Scholar
  111. 112.
    Tsuchida, E., Kaneko, M., Nishide, H.: J. Phys. Chem. 90, in press (1986)Google Scholar

Copyright information

© Springer-Verlag 1986

Authors and Affiliations

  • Eishun Tsuchida
    • 1
  • Hiroyuki Nishide
    • 1
  1. 1.Department of Polymer ChemistryWaseda UniversityTokyoJapan

Personalised recommendations