Abstract
Central nervous system (CNS) infections are difficult to diagnose and manage resulting in high mortality and morbidity due to neurological sequelae like cognitive impairment and seizure disorders. A plethora of organisms including viruses, bacteria, fungi, and parasites may invade the CNS. The antimicrobial choice is limited due to physiological barriers in the CNS. Brain abscesses are focal suppurative lesions caused mainly by bacteria including mycobacteria, fungi, and parasites. The immunocompromised host is more vulnerable. Effective management often includes surgery along with supportive care especially care of the raised intracranial pressure. Antibiotic duration is prolonged, often more than eight weeks, Repeated brain imaging is necessary to ascertain the resolution of the lesion.
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References
Tunkel AR. Approach to the patient with central nervous system infection. In: Mandell GL, Bennett JE, Dolin R, editors. Mandell, Douglas, and Bennet’s principles and practice of infectious diseases, vol. 1. Philadelphia: Churchill Livingstone (Elsevier); 2010. p. 1183–8.
Tunkel AR. Brain abscess. In: Mandell GL, Bennett JE, Dolin R, editors. Mandell, Douglas, and Bennet’s principles and practice of infectious diseases, vol. 1. Philadelphia: Churchill Livingstone (Elsevier); 2010. p. 1265–78.
Roos KL, Tyler KL. Meningitis, encephalitis, brain abscess, and empyema. In: Kasper DL, Fauci AS, Hauser SL, Longo DL, Jameson JL, Loscalzo J, editors. Harrison’s principles of internal medicine, vol. 2. McGraw Hill; 2015. p. 883–905.
Brouwer CM, Tunkel AR, McKhann GM II, van de Beek D. Brain abscess. N Engl J Med. 2014;371:447–56.
Modi M, Prabhakar S, Gupta K, Vasishta RK, Ahuja C, Khandelwal N, Kajsekhar V. CNS tuberculomas. In: Chopra JS, Sawhney IMS, editors. Neurology in tropics. Elsevier; 2016. p. 206–21.
Index-TB Guidelines—Guidelines on extra-pulmonary tuberculosis for India. From Central TB Division, Ministry of Health and Family Welfare, Govt Of India.
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Shobhana, A. (2024). Brain Abscess. In: Oli, K.K., Shrestha, G.S., Ojha, R., Pal, P.K., Pandey, S., Das, B. (eds) Case-based Approach to Common Neurological Disorders. Springer, Singapore. https://doi.org/10.1007/978-981-99-8676-7_9
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DOI: https://doi.org/10.1007/978-981-99-8676-7_9
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