Skip to main content

Diagnosis and Treatment of Drug-Resistant Cervical Tuberculous Lymphadenitis

  • Chapter
  • First Online:
Diagnostic Imaging of Drug Resistant Pulmonary Tuberculosis

Abstract

Tuberculosis, a chronic disease induced by infection of mycobacterium tuberculosis (MTB), is one of main diseases endangering human health. Tuberculosis may affect almost all organs and tissues in the body. Clinically, it can be divided into pulmonary tuberculosis and extra-pulmonary tuberculosis according to the different sites infected in patients. Among all extra-pulmonary tuberculosis, tuberculous lymphadenitis is the most common one, and its most common site is the neck [1]. Cervical tuberculous lymphadenitis (CTL) accounts for 4.0–5.1% of all tuberculosis cases, and 20.3–50% of extra-pulmonary tuberculosis [2]. In recent years, Indian scholar Akkara et al. [3] showed that cervical lymph node tuberculosis accounted for 5.36% of all tuberculosis cases, so cervical lymph node tuberculosis is quite common clinically.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Gautam H, Agrawal SK, Verma SK, et al. Cervical tuberculous lymphadenitis: clinical profile and diagnostic modalities [J]. Int J Mycobacter. 2018;7(3):212–6.

    Article  Google Scholar 

  2. Technical Guidance Group of the Fifth National Epidemiological Sampling Survey of tuberculosis, and Office of the Fifth National Epidemiological Sampling Survey of Tuberculosis. Report on the fifth national epidemiological sampling survey of tuberculosis in 2010. Chin J Antituberc. 2012;34(8):485–508.

    Google Scholar 

  3. Akkara SA, Singhania A, Akkara AG, et al. A study of manifestations of extrapulmonary tuberculosis in the ENT region [J]. Indian J Otolaryngol Head Neck Surg. 2014;66(1):46–50.

    Article  PubMed  Google Scholar 

  4. Zeng Z, Zhou J, Tao J, et al. Application of gene chip to the diagnosis of tuberculosis lymphadenitis and analysis on its drug resistance [J/OL]. Chin J Clin (Electr Ed). 2020;14(11):890–4.

    Google Scholar 

  5. Yu X, Fang X. The role of fine needle aspiration cytology in combination with fluorescence quantify polymerase chain reaction in diagnosing tuberculosis lymphadenitis [J]. Chin J Tuberc Resp Dis. 2009;32(1):51–4.

    Google Scholar 

  6. Romdhane E, Arfaoui A, Benabdessalem C, et al. Performance of GeneXpert ultra in the diagnosis of tuberculous cervical lymphadenitis in formalin fixed paraffin embedded tissues [J]. Tuberculosis. 2020;125:102–12.

    Article  Google Scholar 

  7. Raja R, Sreeramulu PN, Dave P, et al. GeneXpert Assay—a cutting-edge tool for rapid tissue diagnosis of tuberculous lymphadenitis [J]. J Clin Tuberc Other Mycobact Dis. 2020;21:100204.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Tadesse M, Abebe G, Abdissa K, Aragaw D, Abdella K, Bekele A, et al. GeneXpert MTB/ RIF assay for the diagnosis of tuberculous lymphadenitis on concentrated fine needle aspirates in high tuberculosis burden settings. PLoS One. 2015;10(9):e0137471.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Yang C, Dai X, Li Q, et al. A clinical analysis on 210 cases of cervical tuberculosis lymphadenitis [J]. Chin J Antituberc. 2017;39(02):169–73.

    Google Scholar 

  10. Guo B, Liu W, Shao B, et al. The role of cervical lymphadenectomy in treating cervical tuberculosis lymphadenitis [J]. Chin J Tuberc Resp Dis. 1998;21(6):352–4.

    CAS  Google Scholar 

  11. Lee Y, Park KS, Chung SY. Cervical tuberculous lymphadenitis: CT findings [J]. J Comput Assist Tomogr. 1994;18(3):370075.

    Article  Google Scholar 

  12. Jiang T, Xue L, Lian G, et al. A research on clinical application of micro-invasiveness in combination with negative pressure wound therapy to surgery of cervical tuberculosis lymphadenitis [J]. Chin J Biomed Eng. 2021;27(01):47–52.

    Google Scholar 

  13. Wang H, Zheng S, Huang P, et al. Retrospective analysis of functional regional cervical lymph node dissection in the treatment of abscess and ulcerated cervical lymphatic tuberculosis [J/CD]. Electr J Emerg Infect Dis. 2021;6(4):275–9.

    Google Scholar 

  14. Wang Z, Liu J, Li J, et al. Analysis of factors related to responses in 173 cases of cervical tuberculosis lymphadenitis to surgical treatment [J]. Chin J Antituberc. 2016;38(7):559–63.

    Google Scholar 

  15. Tuberculosis Branch of Chinese Medical Association. Expert consensus on the treatment of multidrug resistant and rifampicin resistant tuberculosis in China (2019 edition). Chin J Tuberc Resp Dis. 2019;42(10):733–40.

    Google Scholar 

  16. Sayaka O, Muneo N, Ayumi M, et al. A clinical review of 38 cases of cervical tuberculous lymphadenitis in Japan―the role of neck dissection [J]. Auris Nasus Larynx. 2017;120(3):276–7.

    Google Scholar 

  17. Zheng Q-t, Dong C-f, Lu P-x, et al. The comparative analysis of color doppler ultrasonography and multi-slice CT scan in the diagnosis of cervical lymph node tuberculosis[J].Electronic journal of. Emerg Infect Dis. 2017;2(3):218–22.

    Google Scholar 

  18. Xiuling H, Changfeng D. The application value of new ultrasound technique in cervical lymph node tuberculosis[J].Electronic journal of. Emerg Infect Dis. 2021;6(3):255–9.

    Google Scholar 

  19. Zhao D, Wang M, Liu J, et al. An observation of effectiveness of functional cervical lymphadenectomy in treating cervical tuberculosis lymphadenitis [J]. Chin J Difficult Complicated Cases. 2019;18(1):60–4.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 People's Medical Publishing House, PR of China

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Wang, Hj., Lu, Hz., Yi, Yx., Luo, Zh., He, Yl. (2023). Diagnosis and Treatment of Drug-Resistant Cervical Tuberculous Lymphadenitis. In: Lu, PX., Lu, Hz., Yi, Yx. (eds) Diagnostic Imaging of Drug Resistant Pulmonary Tuberculosis. Springer, Singapore. https://doi.org/10.1007/978-981-99-8339-1_12

Download citation

  • DOI: https://doi.org/10.1007/978-981-99-8339-1_12

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-99-8338-4

  • Online ISBN: 978-981-99-8339-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics