Abstract
Nowadays, textile products are being used in several sectors for different purposes beyond imagination. Among these, a very important and emerging domain is medical and healthcare domain. Biopolymers, such as alginate, chitosan, cellulose, gelatin, and collagen, are polymers of natural origin produced by living organisms. They are known to be highly biocompatible and biodegradable. Current studies reported that biopolymers exhibit various health beneficial properties such as antimicrobial, anti-inflammatory, hemostatic, cell proliferative, and antioxidant activities. So biopolymers could be used in the production of medical and paramedical textile devices, with drug delivery property, in the form of fibers, nanofibers, nonwoven, fabrics, sponges, nanoparticles and thin films. In addition, thank to its wound healing properties, biopolymers could be employed in the treatment of soft tissue infections. Biomaterials are able to slow down, then stop the bleeding of recent wounds by activating platelet agglutination. They could also promote the regeneration of tissue cells like muscles, skin, and nerves. Moreover, biopolymers-based nonwoven textile wound dressings can be used drug delivery carriers for wound healing. This paper highlights the structure and characteristics of natural biopolymers. The recent research advances and trends of biomass-derived materials and their derivatives in healthcare and medical textile devices for promotion of wound healing, tissue regeneration, and drug delivery in soft tissue diseases are investigated.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
King, M. W., Gupta, B. S., Guidoin, R.: Biotextiles as Medical Implants, Elsevier, Amsterdam, Netherlands, 2017.
Petros, S., Tesfaye, T., Ayele, M.: A Review on Gelatin Based Hydrogels for Medical Textile Applications. Journal of Engineering (2020). ID 8866582. https://doi.org/10.1155/2020/8866582.
Sumithra, M.: Development of medical textile product using chitosan incorporated herbal extract (Aristolochia bracteolate). Int. J. Pharm. Life Sci. 9(3), 5748–5754 (2018).
Akshay Kumar, K. P., Zare, E. N., Torres-Mendieta, R., Waclawek, S., Makvandi, P., Cernik, M.: Electrospun fibers based on botanical, seaweed, microbial, and animal sourced biomacromolecules and their multidimensional applications. Int. J. Biol. Macromol. 171, 130–149 (2021).
Li, D., Wang, Y., Huang, W., Gong, H.: Biomass-derived fiber materials for biomedical applications. Front. Mater. 10, 1058050 (2023).
Zhao, W., Liu, W., Li, J., Lin, X., Wang, Y.: Preparation of animal polysaccharides nanofibers by electrospinning and their potential biomedical applications. J. Biomed. Mater. Res. Part A 103, 807–818 (2015).
Alminderej, F.M., Ammar, C., El-Ghoul, Y.: Functionalization, characterization and microbiological performance of new biocompatible cellulosic dressing grafted chitosan and Suaeda fruticose polysaccharide extract. Cellulose 28, 9821–9835 (2021).
Jahandideh, A., Ashkani, M., Moini, N.: Biopolymers in textile industries. In Sabu Thomas, Sreeraj Gopi, Augustine Amalraj Editor(s), Biopolymers and their Industrial Applications, Chapter 8, pp. 193–218, Elsevier (2021).
Joyce, K., Fabra, G.T., Bozkurt, Y. et al.: Bioactive potential of natural biomaterials: identification, retention and assessment of biological properties. Sig Transduct Target Ther. 6, 122 (2021).
Elamri, A., Zdiri, K., Hamdaoui, M., Harzallah, O.: Chitosan: A biopolymer for textile processes and products. Textile Research Journal. 93(5–6), 1456–1484 (2023).
Elamri, A., Zdiri, K., Bouzir, D., Hamdaoui M.: Use of Chitosan as Antimicrobial, Antiviral and Antipollution Agent in Textile Finishing. Vlakna a Textil 29(3), 51–70 (2022).
Ahmad, S. I., Ahmad, R., Khan, M. S., Kant, R., Shahid, S., Gautam, L., et al.: Chitin and its derivatives: Structural properties and biomedical applications. Int. J. Biol. Macromol. 164, 526–539 (2020).
Saltz, A., Kandalam, U.: Mesenchymal stem cells and alginate microcarriers for craniofacial bone tissue engineering: A review. J. Biomed. Mater. Res. A 104, 1276–1284 (2016).
Hecht, H.; Srebnik, S.: Structural Characterization of Sodium Alginate and Calcium Alginate. Biomacromolecules 17, 2160–2167 (2016).
Wróblewska-Krepsztul J., Rydzkowski T., Michalska-Pożoga I., Thakur V.K.: Biopolymers for Biomedical and Pharmaceutical Applications: Recent Advances and Overview of Alginate Electrospinning. Nanomaterials (Basel) 9(3), 404 (2019).
Tan, G., Wang, L., Pan, W., Chen, K.: Polysaccharide Electrospun Nanofibers for Wound Healing Applications. Int J Nanomedicine 17, 3913–3931 (2022).
Castro, K.C., Campos, M.G.N., Mei, L.H.I.: Hyaluronic acid electrospinning: challenges, applications in wound dressings and new perspectives. Int J Biol Macromol. 173, 251–266 (2021).
Frenkel, J.S.: The role of hyaluronan in wound healing. Int Wound J 11, 159–163 (2014).
Maia, J., Evangelista, M.B., Gil, H., Ferreira, L.: Dextran-based materials for biomedical applications. Res. Signpost 37661, 31–53 (2014).
Samrot, A.V., Sathiyasree, M., Rahim, S.B.A., et al.: Scaffold Using Chitosan, Agarose, Cellulose, Dextran and Protein for Tissue Engineering-A Review. Polymers (Basel) 15(6), 1525 (2023).
Chattopadhyay, S., Raines, R.T.: Review collagen-based biomaterials for wound healing: Collagen-Based Biomaterials. Biopolymers 101, 821–833 (2014).
Ricard-Blum, S.: The Collagen Family. Cold Spring Harb Perspect Biol 3, a004978–a004978 (2011).
Tonndorf, R., Aibibu, D., Cherif, C.: Collagen multifilament spinning. Mater Sci Eng C Mater Biol Appl. 106, 110105 (2020).
Wang, Z., Zhang, Y., Zhang, J., Huang, L., Liu, J., Li, Y., Zhang, G., Kundu, S.C., Wang, L.: Exploring natural silk protein sericin for regenerative medicine: an injectable, photoluminescent, cell-adhesive 3D hydrogel. Sci. Rep. 4, 7064 (2014).
Kasoju, N. Bora, U. Silk fibroin in tissue engineering. Adv. Healthcare Mater. 1, 319 (2012).
Gil, E.S., Panilaitis, B., Bellas, E., Kaplan, D. L. Functionalized silk biomaterials for wound healing Adv. Healthcare Mater. 2, 206 (2013).
Zhang, W., Chen, L., Chen, et al. Silk Fibroin Biomaterial Shows Safe and Effective Wound Healing in Animal Models and a Randomized Controlled Clinical Trial. Adv. Healthcare Mater. 6, 1700121 (2017).
Fearing, B.V., Van Dyke, M.E.: In vitro response of macrophage polarization to a keratin biomaterial. Acta Biomater. 10, 3136–3144 (2014).
Yao, C.-H., Lee, C.Y., Huang, C.H., Chen, Y.S., Chen, K.Y.: Novel bilayer wound dressing based on electrospun gelatin/keratin nanofibrous mats for skin wound repair. Mater. Sci. Eng. C 79, 533–540 (2017).
Zarei, M., Tanideh, N., Zare, S., Aslani, F.S., Koohi-Hosseinabadi, O., Rowshanghias, A., Pourjavaheri, F., Mehryar, P., Muthuraj, R.: Electrospun poly(3-hydroxybutyrate)/chicken feather-derived keratin scaffolds: Fabrication, in vitro and in vivo biocompatibility evaluation. J. Biomater. Appl. 34, 741–752 (2020).
Akhmetova, A., Heinz, A.: Electrospinning Proteins for Wound Healing Purposes: Opportunities and Challenges. Pharmaceutics 13, 4 (2021).
Parham, S., Kharazi, A.Z., Bakhsheshi-Rad, H.R., Kharaziha, M., Ismail, A.F., Sharif, S., Razzaghi, M., RamaKrishna, S. and Berto, F.: Antimicrobial Synthetic and Natural Polymeric Nanofibers as Wound Dressing: A Review. Adv. Eng. Mater. 24, 2101460 (2022).
Hong, Y., Zhu, X., Wang, P., Fu, H., Deng, C., Cui, L., Wang, Q., Fan, X.: Tyrosinase-Mediated Construction of a Silk Fibroin/Elastin Nanofiber Bioscaffold. Appl Biochem Biotechnol. 178(7), 1363–1376 (2016).
Chong, C., Wang, Y., Fathi, A., Parungao, R., Maitz, P.K., Li, Z.: Skin wound repair: Results of a pre-clinical study to evaluate electropsun collagen-elastin-PCL scaffolds as dermal substitutes. Burns. 45(7), 1639–1648 (2019).
Mendes, A.C., Stephansen, K., Chronakis, I.S.: Electrospinning of food proteins and polysaccharides. Food Hydrocoll. 68, 53–68 (2017).
Wsoo, M.A., Shahir, S., Mohd Bohari, S.P., Nayan, N.H.M., Razak, S.I.A.: A review on the properties of electrospun cellulose acetate and its application in drug delivery systems: A new perspective. Carbohydr. Res. 491, 107978 (2020).
Poshina, D., Otsuka, I.: Electrospun Polysaccharidic Textiles for Biomedical Applications. Textiles 1, 152–169 (2021).
Chee, B.S., Nugent, M.: Electrospun natural polysaccharide for biomedical application. In Natural Polysaccharides in Drug Delivery and Biomedical Applications, Hasnain, M.S., Nayak, A.K., Eds., Chapter 26-pp. 589–615, Academic Press: Cambridge, MA, USA (2019).
Mostafalu, P., Kiaee, G., Giatsidis, et al.: A textile dressing for temporal and dosage controlled drug delivery. Adv. Funct. Mater. 27(41), 1702399 (2017).
Bakhsheshi-Rad, H. R., Ismail, A. F., Aziz, M., Akbari, M., Hadisi, Z., Omidi, M., et al.: Development of the PVA/CS nanofibers containing silk protein sericin as a wound dressing: In vitro and in vivo assessment. Int. J. Biol. Macromol. 149, 513–521 (2020).
Simoes, D., Miguel, S. P., Ribeiro,M. P., Coutinho, P.,Mendonca, A. G., Correia, I. J.: Recent advances on antimicrobial wound dressing: A review. Eur. J. Pharm. Biopharm. 127, 130–141(2018).
Yuan, M., Dai, F., Li, D., Fan, Y., Xiang, W., Tao, F., et al.: Lysozyme/collagen multilayers layer-by-layer deposited nanofibers with enhanced biocompatibility and antibacterial activity. Mater Sci. Eng. C Mater Biol. Appl. 112, 110868 (2020).
Varaprasad, K., Jayaramudu, T., Kanikireddy, V., Toro, C., Sadiku, E.R.: Alginate-based composite materials for wound dressing application: A mini review. Carbohydr Polym. 15(236), 116025 (2020).
Shalumon, K.T., Anulekha, K.H., Girish, C.M., Prasanth, R., Nair, S.V., Jayakumar, R.: Single step electrospinning of chitosan/poly(caprolactone) nanofibers using formic acid/acetone solvent mixture. Carbohydr. Polym. 80, 413–419 (2010).
Kang, Y.M., Lee, B.N., Ko, J.H., Kim, G.H., Kang, K.N., Kim, D.Y., Kim, J.H., Park, Y.H., Chun, H.J., Kim, C.H.: In vivo biocompatibility study of electrospun chitosan microfiber for tissue engineering. Int. J. Mol. Sci. 11, 4140–4148 (2010).
Zhang, X., Wang, C., Liao, M., Dai, L., Tang, Y., Zhang, H., Coates, P., Sefat, F., Zheng, L., Song, J.: Aligned electrospun cellulose scaffolds coated with rhBMP for both in vitro and in vivo bone tissue engineering. Carbohydr. Polym. 213, 27–38 (2019).
Zhao, X., Zhou, L., Li, Q., Zou, Q., Du, C.: Biomimetic mineralization of carboxymethyl chitosan nanofibers with improved osteogenic activity in vitro and in vivo. Carbohydr. Polym. 195, 225–234 (2018).
Zha, F., Chen, W., Hao, L., Wu, C., Lu, M., Zhang, L., Yu, D.: Electrospun cellulose-based conductive polymer nanofibrous mats: Composite scaffolds and their influence on cell behavior with electrical stimulation for nerve tissue engineering. Soft Matter 16, 6591–6598 (2020).
Joy, J., Pereira, J., Aid-Launais, R., Pavon-Djavid, G., Ray, A.R., Letourneur, D., Meddahi-Pellé, A., Gupta, B.: Gelatin-Oxidized carboxymethyl cellulose blend based tubular electrospun scaffold for vascular tissue engineering. Int. J. Biol. Macromol. 107, 1922–1935 (2018).
Zhang, K., Fan, L., Yan, Z., Yu, Q., Mo, X.: Electrospun biomimic nanofibrous scaffolds of silk fibroin/hyaluronic acid for tissue engineering. J. Biomater. Sci. Polym. Ed. 23, 1185–1198 (2012).
Soni, B.: Cellulose-Based Graft Copolymers, Thakur, V.K. Eds, Taylor and Francis, London (2015).
Rostamitabar, M., Abdelgawad, A.M., Jockenhoevel, S. and Ghazanfari, S.: Drug-Eluting Medical Textiles: From Fiber Production and Textile Fabrication to Drug Loading and Delivery. Macromol. Biosci. 21, 2100021 (2021).
Tungprapa, S., Jangchud, I., and Supaphol, P.: Release characteristics of four model drugs from drug-loaded electrospun cellulose acetate fiber mats. Polymer 48 (17), 5030–5041 (2007).
Chen, Y., Qiu, Y., Chen, W., and Wei, Q.: Electrospun thymol-loaded porous cellulose acetate fibers with potential biomedical applications. Mater Sci. Eng. C Mater Biol. Appl. 109, 110536 (2020).
Oprea, M., and Voicu, S. I.: Recent advances in composites based on cellulose derivatives for biomedical applications. Carbohydr. Polym. 247, 116683 (2020).
Hassabo, A., Zayed, M., Bakr, M., Othman, H.: The Utilisation of Gelatin Biopolymer in Textile Wet Processing. Journal of Textiles, Coloration and Polymer Science 19(2), 125–136 (2022).
Soares, R.M.D., Siqueira, N.M., Prabhakaram, M.P., Ramakrishna, S.: Electrospinning and electrospray of bio-based and natural polymers for biomaterials development. Mater. Sci. Eng. C-Mater. Biol. Appl. 92, 969–982 (2018).
Troy, E., Tilbury, M.A., Power, A.M., Wall, J.G.: Nature-Based Biomaterials and Their Application in Biomedicine. Polymers 13, 3321 (2021).
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2024 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
About this paper
Cite this paper
Elamri, A., Zdiri, K., Hamdaoui, M. (2024). Application of Biopolymers in Medical Textiles: Myriad of Opportunities. In: Abdessalem, S.B., Hamdaoui, M., Baffoun, A., Elamri, A. (eds) Proceedings of the Second International Conference of Innovative Textiles and Developed Materials-ITDM’2; 05-06 May 2023; Tunisia. ITDM 2023. Springer, Singapore. https://doi.org/10.1007/978-981-99-7950-9_15
Download citation
DOI: https://doi.org/10.1007/978-981-99-7950-9_15
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-99-7949-3
Online ISBN: 978-981-99-7950-9
eBook Packages: Chemistry and Materials ScienceChemistry and Material Science (R0)