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Interstitial Lung Disease in Connective Tissue Disease

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Radiology Illustrated: Chest Radiology

Part of the book series: Radiology Illustrated ((RADILL))

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Abstract

Connective tissue disease (CTDs) showing features of interstitial lung disease (ILD) pattern include systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), systemic sclerosis (SSc), dermatomyositis (DM) and polymyositis (PM), ankylosing spondylitis (AS), Sjögren’s syndrome (SS), and mixed connective tissue disease (MCTD). Histopathologically, interstitial lung diseases associated with CTD are diverse and include nonspecific interstitial pneumonia (NSIP), usual interstitial pneumonia (UIP), cryptogenic organizing pneumonia (COP), apical fibrosis, diffuse alveolar damage (DAD), and lymphoid interstitial pneumonia (LIP) patterns (NSIP accounts for large proportion, especially in SSc, DM and PM, and MCTD. More favorable prognosis in interstitial pneumonia associated with CTDs than in idiopathic interstitial pneumonias (IIPs) may be explained by the larger proportion of NSIP pattern than UIP pattern. Thin-section CT (TSCT) appears to help characterize and determine the extent of ILD in CTDs.

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Authors and Affiliations

  1. Department of Radiology, Sungkyunkwan University School of Medicine (SKKU-SOM), Samsung ChangWon Hospital, Changwon, Kyongsang-namdo, Korea (Republic of)

    Kyung Soo Lee

  2. Department of Radiology, Samsung Medical Center, Seoul, Korea (Republic of)

    Kyung Soo Lee

  3. Department of Pathology, Samsung Medical Center, Seoul, Korea (Republic of)

    Joungho Han

  4. Department of Medicine, Samsung Medical Center, Seoul, Korea (Republic of)

    Man Pyo Chung

  5. Department of Radiology, Pusan National University School of Medicine, Yangsan, Kyongsang-namdo, Korea (Republic of)

    Yeon Joo Jeong

Authors
  1. Kyung Soo Lee
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  2. Joungho Han
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  4. Yeon Joo Jeong
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Correspondence to Kyung Soo Lee .

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Lee, K.S., Han, J., Chung, M.P., Jeong, Y.J. (2023). Interstitial Lung Disease in Connective Tissue Disease. In: Radiology Illustrated: Chest Radiology. Radiology Illustrated. Springer, Singapore. https://doi.org/10.1007/978-981-99-6633-2_28

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  • DOI: https://doi.org/10.1007/978-981-99-6633-2_28

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-99-6632-5

  • Online ISBN: 978-981-99-6633-2

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