Abstract
Ground-glass opacity (GGO) is caused by partial displacement of air in lung parenchyma. The opacity is caused by partial filling of airspaces, interstitial thickening (due to fluid, cells, or fibrosis), partial collapse of alveoli, and increased capillary blood volume. Without reticulation, the GGO areas usually represent active inflammatory or reversible disease state.
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References
Mueller-Mang C, Grosse C, Schmid K, Stiebellehner L, Bankier AA. What every radiologist should know about idiopathic interstitial pneumonias. Radiographics. 2007;27:595–615.
Lee KS, Kullnig P, Hartman TE, Muller NL. Cryptogenic organizing pneumonia: CT findings in 43 patients. AJR Am J Roentgenol. 1994;162:543–6.
Kim Y, Lee KS, Choi DC, Primack SL, Im JG. The spectrum of eosinophilic lung disease: radiologic findings. J Comput Assist Tomogr. 1997;21:920–30.
Min JH, Lee HY, Lim H, et al. Drug-induced interstitial lung disease in tyrosine kinase inhibitor therapy for non-small cell lung cancer: a review on current insight. Cancer Chemother Pharmacol. 2011;68:1099–109.
Kim EA, Lee KS, Johkoh T, et al. Interstitial lung diseases associated with collagen vascular diseases: radiologic and histopathologic findings. Radiographics. 2002;22(Suppl 1):S151–65.
Katzenstein AL, Fiorelli RF. Nonspecific interstitial pneumonia/fibrosis. Histologic features and clinical significance. Am J Surg Pathol. 1994;18:136–47.
Travis WD, Hunninghake G, King TE Jr, et al. Idiopathic nonspecific interstitial pneumonia: report of an American Thoracic Society Project. Am J Respir Crit Care Med. 2008;177:1338–47.
Kligerman SJ, Groshong S, Brown KK, Lynch DA. Nonspecific interstitial pneumonia: radiologic, clinical, and pathologic considerations. Radiographics. 2009;29:73–87.
Park IN, Kim DS, Shim TS, et al. Acute exacerbation of interstitial pneumonia other than idiopathic pulmonary fibrosis. Chest. 2007;132:214–20.
Tsubamoto M, Muller NL, Johkoh T, et al. Pathologic subgroups of nonspecific interstitial pneumonia: differential diagnosis from other idiopathic interstitial pneumonias on high-resolution computed tomography. J Comput Assist Tomogr. 2005;29:793–800.
Kim TS, Lee KS, Chung MP, et al. Nonspecific interstitial pneumonia with fibrosis: high-resolution CT and pathologic findings. AJR Am J Roentgenol. 1998;171:1645–50.
Yousem SA, Colby TV, Gaensler EA. Respiratory bronchiolitis-associated interstitial lung disease and its relationship to desquamative interstitial pneumonia. Mayo Clin Proc. 1989;64:1373–80.
Vassallo R. Diffuse lung diseases in cigarette smokers. Semin Respir Crit Care Med. 2012;33:533–42.
Hartman TE, Primack SL, Swensen SJ, Hansell D, McGuinness G, Muller NL. Desquamative interstitial pneumonia: thin-section CT findings in 22 patients. Radiology. 1993;187:787–90.
Hidalgo A, Franquet T, Gimenez A, Bordes R, Pineda R, Madrid M. Smoking-related interstitial lung diseases: radiologic–pathologic correlation. Eur Radiol. 2006;16:2463–70.
Okada F, Ando Y, Yoshitake S, et al. Clinical/pathologic correlations in 553 patients with primary centrilobular findings on high-resolution CT scan of the thorax. Chest. 2007;132:1939–48.
Hansell DM, Wells AU, Padley SP, Muller NL. Hypersensitivity pneumonitis: correlation of individual CT patterns with functional abnormalities. Radiology. 1996;199:123–8.
Moon JH, Kim EA, Lee KS, Kim TS, Jung KJ, Song JH. Cytomegalovirus pneumonia: high-resolution CT findings in ten non-AIDS immunocompromised patients. Korean J Radiol. 2000;1:73–8.
Franquet T, Lee KS, Muller NL. Thin-section CT findings in 32 immunocompromised patients with cytomegalovirus pneumonia who do not have AIDS. AJR Am J Roentgenol. 2003;181:1059–63.
Chung MP, Yi CA, Lee HY, Han J, Lee KS. Imaging of pulmonary vasculitis. Radiology. 2010;255:322–41.
Morell F, Roger A, Reyes L, Cruz MJ, Murio C, Munoz X. Bird fancier’s lung: a series of 86 patients. Medicine (Baltimore). 2008;87:110–30.
Lara AR, Schwarz MI. Diffuse alveolar hemorrhage. Chest. 2010;137:1164–71.
Selman M, Pardo A, King TE Jr. Hypersensitivity pneumonitis: insights in diagnosis and pathobiology. Am J Respir Crit Care Med. 2012;186:314–24.
Selman M, Buendia-Roldan I. Immunopathology, diagnosis, and management of hypersensitivity pneumonitis. Semin Respir Crit Care Med. 2012;33:543–54.
Small JH, Flower CD, Traill ZC, Gleeson FV. Air-trapping in extrinsic allergic alveolitis on computed tomography. Clin Radiol. 1996;51:684–8.
Franquet T, Hansell DM, Senbanjo T, Remy-Jardin M, Muller NL. Lung cysts in subacute hypersensitivity pneumonitis. J Comput Assist Tomogr. 2003;27:475–8.
Silva CI, Churg A, Muller NL. Hypersensitivity pneumonitis: spectrum of high-resolution CT and pathologic findings. AJR Am J Roentgenol. 2007;188:334–44.
Wallace JM, Hannah J. Cytomegalovirus pneumonitis in patients with AIDS. Findings in an autopsy series. Chest. 1987;92:198–203.
de Maar EF, Verschuuren EA, Harmsen MC, The TH, van Son WJ. Pulmonary involvement during cytomegalovirus infection in immunosuppressed patients. Transpl Infect Dis. 2003;5:112–20.
Lombard CM, Colby TV, Elliott CG. Surgical pathology of the lung in anti-basement membrane antibody-associated Goodpasture’s syndrome. Hum Pathol. 1989;20:445–51.
Primack SL, Miller RR, Muller NL. Diffuse pulmonary hemorrhage: clinical, pathologic, and imaging features. AJR Am J Roentgenol. 1995;164:295–300.
Cheah FK, Sheppard MN, Hansell DM. Computed tomography of diffuse pulmonary haemorrhage with pathological correlation. Clin Radiol. 1993;48:89–93.
Cha MJ, Lee KS, Hwang HS, et al. Pulmonary intravascular lymphomatosis: clinical, CT, and PET findings, correlation of CT and pathologic results, and survival outcome. Radiology. 2016;280:602–10.
Blatman KH, Grammer LC. Chapter 19: Hypersensitivity pneumonitis. Allergy Asthma Proc. 2012;33(Suppl 1):S64–6.
Catherinot E, Lanternier F, Bougnoux ME, Lecuit M, Couderc LJ, Lortholary O. Pneumocystis jirovecii pneumonia. Infect Dis Clin N Am. 2010;24:107–38.
Allen JN, Pacht ER, Gadek JE, Davis WB. Acute eosinophilic pneumonia as a reversible cause of noninfectious respiratory failure. N Engl J Med. 1989;321:569–74.
Cheon JE, Lee KS, Jung GS, Chung MH, Cho YD. Acute eosinophilic pneumonia: radiographic and CT findings in six patients. AJR Am J Roentgenol. 1996;167:1195–9.
Lacasse Y, Girard M, Cormier Y. Recent advances in hypersensitivity pneumonitis. Chest. 2012;142:208–17.
Silver SF, Muller NL, Miller RR, Lefcoe MS. Hypersensitivity pneumonitis: evaluation with CT. Radiology. 1989;173:441–5.
Jaffe ES, Harris NL, Stein H, Vardiman JW, editors. World Health Organization Classification of Tumors. Pathology and genetics of tumours of haematolpoietic and lymphoid tissues. Lyon: IARC Press; 2001.
Nakamichi N, Fukuhara S, Aozasa K, Morii E. NK-cell intravascular lymphomatosis: a mini-review. Eur J Haematol. 2008;81(1):1–7.
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Lee, K.S., Han, J., Chung, M.P., Jeong, Y.J. (2023). Ground-Glass Opacity Without Reticulation. In: Radiology Illustrated: Chest Radiology. Radiology Illustrated. Springer, Singapore. https://doi.org/10.1007/978-981-99-6633-2_21
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DOI: https://doi.org/10.1007/978-981-99-6633-2_21
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