Abstract
Neurofibromatosis (NF) is a hereditary or familial disease caused by the mutation of neurofibromin, a gene on chromosome 17 presenting with neurogenic masses and other abnormalities of the skin, nervous system, bones, and soft tissues. Clinically and genetically, NF is classified in three distinct forms: peripheral type 1 (NF1), central type 2 (NF2), and Schwannomatosis, which is a neurocutaneous syndrome that is clinically and genetically distinct from NF1 and NF2. It is characterized by multiple schwannomas in the absence of the tumor on both vestibular nerves [1].
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Bahk, WJ. (2023). Neurofibromatosis Affecting Bone. In: Diagnosis and Management of Primary Bone Tumors. Springer, Singapore. https://doi.org/10.1007/978-981-99-5498-8_22
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DOI: https://doi.org/10.1007/978-981-99-5498-8_22
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