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Modern Classification of Acute and Chronic Leukemias: Integrating Biology, Clinicopathologic Features, and Genomics

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Pathogenesis and Treatment of Leukemia

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Abstract

The modern classification of acute leukemias and myeloid neoplasms has much refinement incorporating clinicopathologic and genomic features with the objective of defining disease entities with information on the clinical behaviour, pathobiology, and prognosis. In this chapter, we discuss the current classification of acute leukemias and myeloid neoplasms, highlighting the fifth edition of the World Health Organization (WHO) Classification published in 2022, and the International Consensus Classification (ICC) of Myeloid Neoplasms and Acute Leukemia. Details on the classification of acute lymphoblastic leukemia and myeloid neoplasms with germline predisposition are discussed elsewhere.

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Authors and Affiliations

  1. Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine, University of Hong Kong, Hong Kong, China

    Harinder Gill

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  1. Harinder Gill
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Correspondence to Harinder Gill .

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Editors and Affiliations

  1. Department of Medicine, Queen Mary Hospital, Hongkong, Hong Kong

    Harinder Gill

  2. Department of Medicine, Queen Mary Hospital, Hongkong, Hong Kong

    Yok-Lam Kwong

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Gill, H. (2023). Modern Classification of Acute and Chronic Leukemias: Integrating Biology, Clinicopathologic Features, and Genomics. In: Gill, H., Kwong, YL. (eds) Pathogenesis and Treatment of Leukemia. Springer, Singapore. https://doi.org/10.1007/978-981-99-3810-0_2

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  • DOI: https://doi.org/10.1007/978-981-99-3810-0_2

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-99-3809-4

  • Online ISBN: 978-981-99-3810-0

  • eBook Packages: MedicineMedicine (R0)

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