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Management of Relapsed Acute Promyelocytic Leukemia and the Role of Hematopoietic Stem Cell Transplantation

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Pathogenesis and Treatment of Leukemia

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Abstract

This chapter addresses one of the most controversial issues in the management of acute promyelocytic leukemia (APL) which is the optimal management of relapsed APL following second remission and role of hematopoietic stem cell transplantation in APL. Historical data on the outcomes with HSCT in the preoral arsenic trioxide trioxide (ATO) era will be discussed. The role of consolidation and maintenance with oral ATO-based regimens will be discussed.

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Authors and Affiliations

  1. Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China

    Harinder Gill

  2. Department of Medicine, Queen Mary Hospital, Hong Kong, China

    Harinder Gill

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Correspondence to Harinder Gill .

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  1. Department of Medicine, Queen Mary Hospital, Hongkong, Hong Kong

    Harinder Gill

  2. Department of Medicine, Queen Mary Hospital, Hongkong, Hong Kong

    Yok-Lam Kwong

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Gill, H. (2023). Management of Relapsed Acute Promyelocytic Leukemia and the Role of Hematopoietic Stem Cell Transplantation. In: Gill, H., Kwong, YL. (eds) Pathogenesis and Treatment of Leukemia. Springer, Singapore. https://doi.org/10.1007/978-981-99-3810-0_18

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  • DOI: https://doi.org/10.1007/978-981-99-3810-0_18

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