Skip to main content

Nano-Informatics: Studies on Nano Information Platforms and Their Application in Various Sectors

  • Chapter
  • First Online:
Biological Applications of Nanoparticles

Abstract

Nano-informatics is the interdisciplinary area that investigates the application of information technology on nanobiotechnological data. It is already known that nanotechnology has diverse application area in different industrial sectors such as agriculture, biomedical, pharmacy, etc. Basically nano-informatics deals with all “e-data” of nanomaterial from their properties, toxicity, and interactions with biological units. In this chapter, focus is given on the description of computational platforms dealing with nanotechnological data and how it can be helpful to the further research sector. Due to the less amount of nanotechnological data retrieval system, till now very few research are focused on nano-informatics, but as a subset of informatics technology, nano-informatics can be well- collaborated with material science, chemistry, biotechnology, nanotechnology, physics to make a new trend.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 129.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  • Albanese A, Tang PS, Chan WC (2012) The effect of nanoparticle size, shape, and surface chemistry on biological systems. Annu Rev Biomed Eng 14:1–6

    Article  CAS  PubMed  Google Scholar 

  • Av E, Ao E, Ga K, Vy Z (2012) Properties of nanostructures: data acquisition, categorization, and evaluation. Data Sci J 11:126–139

    Article  Google Scholar 

  • Baker NA, Fritts M, Guccione S, Paik DS, Pappu RV, Patri A, Rubin D, Shaw SY, Thomas DG (2009) Nanotechnology Informatics White Paper caBIG National Cancer Institute February 2009 (non-peer reviewed manuscript)

    Google Scholar 

  • Casalini T (2021) Not only in silico drug discovery: Molecular modelling towards in silico drug delivery formulations. J Control Rele 332:390–417

    Google Scholar 

  • Chhabra RS, Bucher JR, Wolfe M, Portier C (2003) Toxicity characterization of environmental chemicals by the US national toxicology program: An overview. Int J Hyg Env Hea 206(4–5):437–445

    Google Scholar 

  • Cpsc D, Doe E, Nih N, Nist N (2012) Nanotechnology knowledge infrastructure: enabling National Leadership in sustainable design

    Google Scholar 

  • De la Iglesia D, Harper S, Hoover MD, Klaessig F, Lippell P, Maddux B, Morse J, Nel A, Rajan K, Reznik-Zellen R, Tuominen MT (2020) Nanoinformatics 2020 roadmap

    Google Scholar 

  • Dias R, Timmers LF, Caceres RA, Azevedo D Jr (2008) Curr Drug Targets 9(12):1040–1047

    Article  CAS  PubMed  Google Scholar 

  • Duhovny D, Nussinov R, Wolfson HJ (2002) Efficient unbound docking of rigid molecules. In: International workshop on algorithms in bioinformatics, vol 17. Springer, Berlin, pp 185–200

    Chapter  Google Scholar 

  • Ewing TJ, Makino S, Skillman AG, Kuntz ID (2001) DOCK 4.0: search strategies for automated molecular docking of flexible molecule databases. J Comput Aided Mol Des 15(5):411–428

    Article  CAS  PubMed  Google Scholar 

  • Gaheen S, Hinkal GW, Morris SA, Lijowski M, Heiskanen M, Klemm JD (2013) caNanoLab: data sharing to expedite the use of nanotechnology in biomedicine. Comput Sci Discov 6(1):014010

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Goodsell DS, Morris GM, Olson AJ (1996) Automated docking of flexible ligands: applications of AutoDock. J Mol Recognit 9(1):1–5

    Article  CAS  PubMed  Google Scholar 

  • Graham LM, Nguyen TM, Lee SB (2011) Nanodetoxification: emerging role of nanomaterials in drug intoxication treatment. Nanomedicine 6(5):921–928

    Article  CAS  PubMed  Google Scholar 

  • Hanwell MD, Curtis DE, Lonie DC, Vandermeersch T, Zurek E, Hutchison GR (2012) Avogadro: an advanced semantic chemical editor, visualization, and analysis platform. J Chem 4(1):1–7

    Google Scholar 

  • Humphrey W, Dalke A, Schulten K (1996) VMD: visual molecular dynamics. J Mol Graph 14(1):33–38

    Article  CAS  PubMed  Google Scholar 

  • Hunter AD (1996) ACD/ChemSketch 1.0 (freeware); ACD/ChemSketch 2.0 and its tautomers, dictionary, and 3D plug-ins; ACD/HNMR 2.0; ACD/CNMR 2.0. ACS Publications, Washington, DC

    Google Scholar 

  • Joy S, Nair PS, Hariharan R, Pillai MR (2006) Detailed comparison of the protein-ligand docking efficiencies of GOLD, a commercial package and ArgusLab, a licensable freeware. In Silico Biol 6(6):601–605

    CAS  PubMed  Google Scholar 

  • Jurj A, Braicu C, Pop LA, Tomulease C, Gherman C, Breindan-Naegoe I (2017) The new era of nanotechnology, an alternative to change cancer treatment. Drug Design, Development and Therapy 11:2871–2890.

    Google Scholar 

  • Kramer B, Rarey M, Lengauer T (1999) Evaluation of the FLEXX incremental construction algorithm for protein–ligand docking. Proteins 37(2):228–241

    Article  CAS  PubMed  Google Scholar 

  • Lai DY (2012) Toward toxicity testing of nanomaterials in the 21st century: a paradigm for moving forward. Wiley Interdiscip Rev Nanomed Nanobiotechnol 4(1):1–5

    Article  CAS  PubMed  Google Scholar 

  • Makarucha AJ, Todorova N, Yarovsky I (2011) Nanomaterials in biological environment: a review of computer modelling studies. Eur Biophys J 40(2):103–115

    Article  CAS  PubMed  Google Scholar 

  • Maojo V, Martin-Sanchez F, Kulikowski C, Rodriguez-Paton A, Fritts M (2010) Nanoinformatics and DNA-based computing: catalyzing nanomedicine. Pediatr Res 67(5):481–489

    Article  CAS  PubMed  Google Scholar 

  • Maojo V, Fritts M, de la Iglesia D, Cachau RE, Garcia-Remesal M, Mitchell JA, Kulikowski C (2012) Nanoinformatics: a new area of research in nanomedicine. Int J Nanomedicine 7:3867

    Article  PubMed  PubMed Central  Google Scholar 

  • Mittal D, Kaur G, Singh P, Yadav K, Ali SA (2020) Nanoparticle-based sustainable agriculture and food science: recent advances and future outlook. Front Nanotechnol 2:10

    Article  Google Scholar 

  • Nwankwo W, Ukhurebor KE (2021) Nanoinformatics: opportunities and challenges in the development and delivery of healthcare products in developing countries. In: IOP conference series: earth and environmental science, vol 655. IOP Publishing, Bristol, p 012018

    Google Scholar 

  • Oliveira AL (2019) Biotechnology, big data and artificial intelligence. Biotechnol J 14(8):1800613

    Article  Google Scholar 

  • Ostraat ML, Mills KC, Guzan KA, Murry D (2013) The nanomaterial registry: facilitating the sharing and analysis of data in the diverse nanomaterial community. Int J Nanomedicine 8(Suppl 1):7

    CAS  PubMed  PubMed Central  Google Scholar 

  • Panneerselvam S, Choi S (2014) Nanoinformatics: emerging databases and available tools. Int J Mol Sci 15(5):7158–7182

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Pautler M, Brenner S (2010) Nanomedicine: promises and challenges for the future of public health. Int J Nanomedicine 5:803

    PubMed  PubMed Central  Google Scholar 

  • Pernaa J, Aksela M, Ghulam SP (2017) Introduction to molecular modeling in chemistry education. University of Helsinki, Helsinki

    Google Scholar 

  • Petrescu I, Lamotte-Brasseur J, Chessa JP, Ntarima P, Claeyssens M, Devreese B, Marino G, Gerday C (2000) Xylanase from the psychrophilic yeast Cryptococcus adeliae. Extremophiles 4(3):137–144

    Article  CAS  PubMed  Google Scholar 

  • Phan JH, Moffitt RA, Stokes TH, Liu J, Young AN, Nie S, Wang MD (2009) Convergence of biomarkers, bioinformatics and nanotechnology for individualized cancer treatment. Trends Biotechnol 27(6):350–358

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Rarey M, Kramer B, Lengauer T, Klebe G (1996) A fast flexible docking method using an incremental construction algorithm. J Mol Biol 261(3):470–489

    Article  CAS  PubMed  Google Scholar 

  • Rose P, Bhat M, Vidhani K, Ajmeri N, Gole A, Ghaisas S (2011) Intelligent informatics platform for nano-agriculture. In: 2011 11th IEEE international conference on nanotechnology. IEEE, New York, pp 916–919

    Chapter  Google Scholar 

  • Rosse C, Mejino JL Jr (2003) A reference ontology for biomedical informatics: the foundational model of anatomy. J Biomed Inform 36(6):478–500

    Article  PubMed  Google Scholar 

  • Ruping K, Sherman BW (2004) Nanoinformatics: Emerging computational tools in nanoscale research. In: Technical proceedings of the 2004 NSTI nanotechnology conference and trade show, vol 3. Tech Connect, Noida, pp 525–528

    Google Scholar 

  • Sarkar B, Verma SK, Akhtar J, Netam SP, Gupta SK, Panda PK, Mukherjee K (2018) Molecular aspect of silver nanoparticles regulated embryonic development in zebrafish (Danio rerio) by Oct-4 expression. Chemosphere 206:560–567

    Article  CAS  PubMed  Google Scholar 

  • Sayle RA, Milner-White EJ (1995) RASMOL: biomolecular graphics for all. Trends Biochem Sci 20(9):374–376

    Article  CAS  PubMed  Google Scholar 

  • Schrödinger L, DeLano W (2020) The PyMOL molecular graphics system, version, vol 2. Schrödinger, New York, NY

    Google Scholar 

  • Scott NR, Chen H, Cui H (2018) Nanotechnology applications and implications of agrochemicals toward sustainable agriculture and food systems. J Agric Food Chem 66(26):6451–6456

    Article  CAS  PubMed  Google Scholar 

  • Sridhar KR, Bärlocher F, Krauss GJ, Krauss G (2005) Response of aquatic hyphomycete communities to changes in heavy metal exposure. Int Rev Hydrobiol 90(1):21–32

    Article  CAS  Google Scholar 

  • Thierry B (2009) Drug nanocarriers and functional nanoparticles: applications in cancer therapy. Curr Drug Deliv 6(4):391–403

    Article  CAS  PubMed  Google Scholar 

  • Thomas DG, Klaessig F, Harper SL, Fritts M, Hoover MD, Gaheen S, Stokes TH, Reznik-Zellen R, Freund ET, Klemm JD, Paik DS (2011) Informatics and standards for nanomedicine technology. Wiley Interdiscip Rev Nanomed Nanobiotechnol 3(5):511–532

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Thomas DG, Gaheen S, Harper SL, Fritts M, Klaessig F, Hahn-Dantona E, Paik D, Pan S, Stafford GA, Freund ET, Klemm JD (2013) ISA-TAB-Nano: a specification for sharing nanomaterial research data in spreadsheet-based format. BMC Biotechnol 13(1):1–5

    Article  Google Scholar 

  • Totrov R, Abagyan R (1997) Proteins 1:215–220

    Article  Google Scholar 

  • Toumey C (2011) Why not zwergo-technology? Nat Nanotechnol 6(7):393–394

    Article  CAS  PubMed  Google Scholar 

  • Verdonk ML, Cole JC, Hartshorn MJ, Murray CW, Taylor RD (2003) Improved protein–ligand docking using GOLD. Proteins 52(4):609–623

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgement

The authors are grateful to the Birla Institute of Technology, Mesra for providing infrastructure and financial support (Institute Research Fellowship) for executing the study.

Multiple Choice Question

  1. 1.

    Toxicity Database is

    1. (a)

      ISA-TAB-Nano

    2. (b)

      TOXNET

    3. (c)

      Nanomaterial Registry

  2. 2.

    ChemSketch is a

    1. (a)

      Modelling software

    2. (b)

      Docking software

    3. (c)

      Visualization software

Short answer type questions

  1. 1.

    Describe about ISA-TAB-Nano.

  2. 2.

    What is Molecular modelling?

  3. 3.

    What are the differences between bioinformatics and nanoinformatics?

  4. 4.

    What is molecular docking?

  5. 5.

    What are the various components of nanoinformatics?

Long answer type questions

  1. 1.

    What is Avogadro software? How it can be helpful in developing nanoparticle structure, describe with example.

  2. 2.

    Describe a docking software that helps in interaction studies of nanoparticles with another biological macromolecule.

  3. 3.

    Make a list of databases that provide information about nanoparticle and toxicity study.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Koel Mukherjee .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Mukherjee, K., Bhadaria, H., Pillai, S., Kumari, M., Sarkar, B. (2023). Nano-Informatics: Studies on Nano Information Platforms and Their Application in Various Sectors. In: Sarkar, B., Sonawane, A. (eds) Biological Applications of Nanoparticles. Springer, Singapore. https://doi.org/10.1007/978-981-99-3629-8_10

Download citation

Publish with us

Policies and ethics