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Development and Growth of the Spine and Lungs

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Paediatric Scoliosis
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Abstract

This chapter explores the normal development and growth of the human spine, with a particular emphasis on its association with thoracic cage and lung development. Spinal development initiates during the embryonic stage with the formation of the notochord and neural tube, leading to the differentiation of somites into the musculoskeletal system. Longitudinal spine growth is influenced by neural stem activity, resulting in varying growth rates for the thoracic and lumbar regions. Any disruption in this process, such as early-onset scoliosis (EOS), can hinder thoracic cage development and lung growth, potentially leading to severe respiratory insufficiency. Early intervention, like opening wedge thoracostomy, is vital in expanding the thoracic cage and maximizing lung growth before bronchial tree development is complete. While conventional spinal instrumentation has limitations in controlling deformities, newer techniques aim to preserve spinal growth and motion. Avoiding extensive spine arthrodesis in young children is crucial to maintain their spinal and thoracic growth potential. Emphasizing a longer, curved spine with preserved growth over early fusion and a shorter, straight spine is gaining acceptance in scoliosis treatment.

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References

  1. Dimeglio A. Growth of the spine before age 5 years. J Pediatr Orthop B. 1992;1(2):102–7.

    Article  Google Scholar 

  2. Morrissy RT, Weinstein SL. Lovell & Winter’s pediatric orthopaedics. Philadelphia: Lippincott Williams & Wilkins; 2001. p. 1496.

    Google Scholar 

  3. Rothman RH, Simeone FA, Herkowitz HN, editors. Rothman–Simeone and Herkowitz’s, the spine. 7th ed. Philadelphia: Elsevier; 2018. p. 2.

    Google Scholar 

  4. Weinstein SL, editor. The pediatric spine: principles and practice. 2nd ed. Philadelphia: Lippincott Williams & Wilkins; 2001. p. 1086.

    Google Scholar 

  5. Diab M, Staheli LT. Practice of paediatric orthopaedics. Philadelphia: Lippincott Williams & Wilkins; 2016.

    Google Scholar 

  6. Zhang H, Sucato DJ. Unilateral pedicle screw epiphysiodesis of the neurocentral synchondrosis. Production of idiopathic-like scoliosis in an immature animal model. J Bone Jt Surg Am. 2008;90(11):2460–9.

    Article  Google Scholar 

  7. Dimeglio A, Canavese F. The growing spine: how spinal deformities influence normal spine and thoracic cage growth. Eur Spine J. 2012;21(1):64–70.

    Article  PubMed  Google Scholar 

  8. Canavese F, Dimeglio A. Normal and abnormal spine and thoracic cage development. World J Orthop. 2013;4(4):167–74.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Helenius IJ. Normal and abnormal growth of spine. In: Yazici M, editor. Non-idiopathic spine deformities in young children. Berlin: Springer; 2011. p. 3–13. https://doi.org/10.1007/978-3-642-19417-7_1.

    Chapter  Google Scholar 

  10. Emans JB, Ciarlo M, Callahan M, Zurakowski D. Prediction of thoracic dimensions and spine length based on individual pelvic dimensions in children and adolescents: an age-independent, individualized standard for evaluation of outcome in early onset spinal deformity. Spine. 2005;30(24):2824–9.

    Article  PubMed  Google Scholar 

  11. Karol LA, Johnston C, Mladenov K, Schochet P, Walters P, Browne RH. Pulmonary function following early thoracic fusion in non-neuromuscular scoliosis. J Bone Jt Surg Am. 2008;90(6):1272–81.

    Article  Google Scholar 

  12. Akbarnia BA, Campbell RM, Dimeglio A, Flynn JM, Redding GJ, Sponseller PD, et al. Fusionless procedures for the management of early-onset spine deformities in 2011: what do we know? J Child Orthop. 2011;5(3):159–72.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Charles YP, Diméglio A, Marcoul M, Bourgin JF, Marcoul A, Bozonnat MC. Influence of idiopathic scoliosis on three-dimensional thoracic growth. Spine. 2008;33(11):1209–18.

    Article  PubMed  Google Scholar 

  14. Pehrsson K, Larsson S, Oden A, Nachemson A. Long-term follow-up of patients with untreated scoliosis. A study of mortality, causes of death, and symptoms. Spine (Phila Pa 1976). 1992;17(9):1091–6.

    Article  CAS  PubMed  Google Scholar 

  15. DeGroodt EG, van Pelt W, Borsboom GJ, Quanjer PH, van Zomeren BC. Growth of lung and thorax dimensions during the pubertal growth spurt. Eur Respir J. 1988;1(2):102–8.

    Article  CAS  PubMed  Google Scholar 

  16. Campbell RM, Hell-Vocke AK. Growth of the thoracic spine in congenital scoliosis after expansion thoracoplasty. J Bone Jt Surg Am. 2003;85(3):409–20.

    Article  Google Scholar 

  17. Campbell RM, Smith MD, Mayes TC, Mangos JA, Willey-Courand DB, Kose N, et al. The characteristics of thoracic insufficiency syndrome associated with fused ribs and congenital scoliosis. J Bone Jt Surg Am. 2003;85(3):399–408.

    Article  Google Scholar 

  18. Mehta HP, Snyder BD, Callender NN, Bellardine CL, Jackson AC. The reciprocal relationship between thoracic and spinal deformity and its effect on pulmonary function in a rabbit model: a pilot study. Spine. 2006;31(23):2654–64.

    Article  PubMed  Google Scholar 

  19. Bess S, Akbarnia BA, Thompson GH, Sponseller PD, Shah SA, El Sebaie H, et al. Complications of growing-rod treatment for early-onset scoliosis: analysis of one hundred and forty patients. J Bone Jt Surg Am. 2010;92(15):2533–43.

    Article  Google Scholar 

  20. McCarthy RE, Sucato D, Turner JL, Zhang H, Henson MAW, McCarthy K. Shilla growing rods in a caprine animal model: a pilot study. Clin Orthop. 2010;468(3):705–10.

    Article  PubMed  Google Scholar 

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Correspondence to Kishore Puthezhath .

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Puthezhath, K. (2023). Development and Growth of the Spine and Lungs. In: Zacharia, B., Raja, S.D.C., KV, N. (eds) Paediatric Scoliosis . Springer, Singapore. https://doi.org/10.1007/978-981-99-3017-3_48

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  • DOI: https://doi.org/10.1007/978-981-99-3017-3_48

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-99-3016-6

  • Online ISBN: 978-981-99-3017-3

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