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Periorbital Skull Base Neoplasms

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Orbital Apex and Periorbital Skull Base Diseases

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Abstract

The anatomical relationship of the orbit and specifically the orbital apex to the skull base makes it vulnerable to neoplastic invasion or extension by skull base and primary periorbital tumors. These lesions, although rare, provide a challenge in terms of diagnosis and treatment given their location. Patients may present with proptosis, ophthalmoplegia, and/or vision loss. Workup involves imaging and biopsy in many cases. They can range from benign histology such as meningiomas to neoplastic pathologies such as aggressive sarcomas. Surgery remains the primary treatment modality in most cases. Characteristics of several tumors and neoplasms that may involve the orbit or orbital apex are discussed in this chapter including sphenoid wing meningiomas, trigeminal schwannomas, sellar region tumors, sinonasal tumors, cavernous angiomas, lymphangiomas, lymphomas, soft tissue neoplasms, and metastases.

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Authors and Affiliations

  1. Department of Neurosurgery, MedStar Georgetown University Hospital, Washington, DC, USA

    Ehsan Dowlati

  2. Department of Neurosurgery, George Washington University Hospital, Washington, DC, USA

    Max Fleisher

  3. Department of Neurosurgery, Lehigh Valley Health Network, Allentown, PA, USA

    Walter C. Jean

  4. Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, FL, USA

    Walter C. Jean

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  1. Ehsan Dowlati
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  2. Max Fleisher
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  3. Walter C. Jean
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Correspondence to Walter C. Jean .

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Editors and Affiliations

  1. Department of Neurosurgery, Queen Elizabeth Hospital, Hong Kong, China

    Tak Lap POON

  2. Department of Neurosurgery, Queen Elizabeth Hospital, Hong Kong, China

    Calvin MAK

  3. Ophthalmology and Visual Sciences, Hong Kong Eye Hospital, Hong Kong, China

    Hunter Kwok Lai YUEN

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Dowlati, E., Fleisher, M., Jean, W.C. (2023). Periorbital Skull Base Neoplasms. In: POON, T.L., MAK, C., YUEN, H.K.L. (eds) Orbital Apex and Periorbital Skull Base Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-99-2989-4_13

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