Skip to main content

Machine Learning Models for Alzheimer’s Disease Detection Using OASIS Data

  • Chapter
  • First Online:
Data Analysis for Neurodegenerative Disorders

Abstract

Early Prediction of Alzheimer’s disease is a challenging task for researchers to contribute. Dementia is the simplest symptom of Alzheimer’s disease. Nowadays, most researchers apply Artificial Intelligence to discover mental disorders like Alzheimer’s, which mostly affect the old age population worldwide. In Alzheimer's disease, the brain is under neurodegenerative changes. As our population ages, more people will be affected by diseases that impact memory functionalities. These repercussions will profoundly affect the person’s social and financial fronts. It is difficult to predict Alzheimer's disease in its early stages. The Medication given early in Alzheimer's disease is more effective and has fewer minor side effects than treatment given later. To find the optimum parameters for Alzheimer's disease prediction, researchers used a variety of algorithms, including Decision Trees, Random Forests, Support Vector Machines, Gradient Boosting, and Voting classifiers. Predictions of Alzheimer's disease are based on data from the Open Access Series of Imaging Studies (OASIS). The performance of machine learning models is tested using measures such as Precision, Recall, Accuracy, and F1-score. Clinicians can use the proposed classification approach to make diagnoses of these disorders. With these ML algorithms, it is extremely beneficial to reduce annual Alzheimer's disease death rates in early diagnosis. On the test data of Alzheimer’s disease, the proposed work demonstrates better results, with the best validation average accuracy of 80%.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Zhang, D., Shen, D.: Predicting future clinical changes of MCI patients using longitudinal and multimodal biomarkers. PLoS ONE 7(3), e33182 (2012). https://doi.org/10.1371/journal.pone.0033182

    Article  Google Scholar 

  2. Batmanghelich, K.N., Ye, D.H., Pohl, K.M., Taskar, B., Davatzikos, C.: Disease classification and prediction via semi-supervised dimensionality reduction. Biomedical Imaging: From Nano to Macro, 2011 IEEE International Symposium on IEEE, pp. 1086–1090 (2011). https://doi.org/10.1109/ISBI.2011.5872590

  3. Ardekani, B.A., Bachman, A.H., Figarsky, K., Sidtis, J.J.: Corpus callosum shape changes in early Alzheimer’s disease: an MRI study using the OASISbraindatabase. Brain Struct. Funct. 219, 343–352 (2014). https://doi.org/10.1007/s00429-013-0503-0

  4. https://en.wikipedia.org/wiki/Precision_and_recall

  5. Marcus, D.S., Wang, T.H., Parker, J., Csernansky, J.G., Morris, J.C., Buckner, R.L.: Open Access Series of Imaging Studies (OASIS): cross-sectional MRI data in young, middle aged, nondemented, and demented older adults. J. Cogn. Neurosci. 19(9), 1498–1507 (2007)

    Article  Google Scholar 

  6. Marcus, D.S., Fotenos, A.F., Csernansky, J.G., Morris, J.C., Buckner, R.L.: Open access series of imaging studies: longitudinal MRI data in nondemented and demented older adults. J. Cogn. Neurosci. 22(12), 2677–2684 (2010)

    Article  Google Scholar 

  7. Islam, J., Zhang, Y.: Early diagnosis of Alzheimer’s disease: a neuroimaging study with deep learning architectures. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition Workshops, pp. 1881–1883 (2018)

    Google Scholar 

  8. Tayal, A., Solanki, A., Singh, S.P.: Integrated frame work for identifying sustainable manufacturing layouts based on big data, machine learning, meta-heuristic and data envelopment analysis. Sustainable Cities and Society (2020)

    Google Scholar 

  9. Singh, S.P., Solanki, A., Singh, T., Tayal, A.: Internet of intelligent things: injection of intelligence into IoT devices. Artificial intelligence to solve pervasive internet of …, (2021)

    Google Scholar 

  10. Kaur, H., Singh, S.P., Bhatnagar, S., Solanki, A.: Intelligent smart home energy efficiency model using artificial intelligence and internet of things. Artificial Intelligence to Solve Pervasive Internet of …, (2021)

    Google Scholar 

  11. Singh, S.P., Sharma, A., Kumar, R.: Designing of fog based FBCMI2E Model using machine learning approaches for intelligent communication systems. Computer Communications (2020)

    Google Scholar 

  12. Solanki, A., Kumar, S., Rohan, C., Singh, S.P., Tayal, A.: Prediction of breast and lung cancer, comparative review and analysis using machine learning techniques. Smart Computing and Self-Adaptive Systems (2021)

    Google Scholar 

  13. Tiwari, S., Kane, L., Koundal, D., Jain, A., Alhudhaif, A., Polat, K., Zaguia, A., Alenezi, F., Althubiti, S.A.: SPOSDS: A smart Polycystic Ovary Syndrome diagnostic system using machine learning. Expert Syst. Appl. 203, 117592 (2022)

    Article  Google Scholar 

  14. Bari Antor, M., Jamil, A. H. M., Mamtaz, M., Monirujjaman Khan, M., Aljahdali, S., Kaur, M., ... & Masud, M. (2021). A comparative analysis of machine learning algorithms to predict alzheimer’s disease. Journal of Healthcare Engineering2021.

    Google Scholar 

  15. Moradi, E., Pepe, A., Gaser, C., Huttunen, H., Tohka, J., Initiative, A.D.N.: Machine learning framework for early MRI-based Alzheimer’s conversion prediction in MCI subjects. Neuroimage 104, 398–412 (2015)

    Article  Google Scholar 

  16. Zhang, Y., Dong, Z., Phillips, P., Wang, S., Ji, G., Yang, J., Yuan, T.F.: Detection of subjects and brain regions related to Alzheimer’s disease using 3D MRI scans based on eigenbrain and machine learning. Front. Comput. Neurosci. 9, 66 (2015)

    Article  Google Scholar 

  17. Magnin, B., Mesrob, L., Kinkingnéhun, S., Pélégrini-Issac, M., Colliot, O., Sarazin, M., Benali, H., et al.: Support vector machine-based classification of Alzheimer’s disease from whole-brain anatomical MRI. Neuroradiology 51(2), 73–83 (2009)

    Article  Google Scholar 

  18. Khan, P., Kader, M.F., Islam, S.R., Rahman, A.B., Kamal, M.S., Toha, M.U., et al.: Machine learning and deep learning approaches for brain disease diagnosis: principles and recent advances. IEEE Access 9, 37622–37655 (2021)

    Article  Google Scholar 

  19. Saratxaga, C.L., Moya, I., Picón, A., Acosta, M., Moreno-Fernandez-de-Leceta, A., Garrote, E., et al.: MRIDeep learning-based solution forAlzheimer’s Disease Prediction. J. Pers. Med (2021)

    Google Scholar 

  20. Sudharsan, M., Thailambal, G.: Alzheimer’s disease prediction using machine learning techniques and principal component analysis (PCA). Materials Today: Proceedings (2021)

    Google Scholar 

  21. Helaly, H.A., Badawy, M., Haikal, A.Y.: Deep learning approach for early detection of Alzheimer’s disease. Cogn Comput. (2021)

    Google Scholar 

  22. Basheer, S., Bhatia, S., Sakri, S.B.: Computational modeling of dementia prediction using deep neural network: analysis on OASIS dataset. IEEE Access 9, 42449–42462 (2021)

    Article  Google Scholar 

  23. Martinez-Murcia, F.J., Ortiz, A., Gorriz, J.M., Ramirez, J., Castillo-Barnes, D.: Studying the manifold structure of Alzheimer’s disease: a deep learning approach using convolutional autoencoders. IEEE J Biomed. Health Inform. 24, 17–26 (2020)

    Article  Google Scholar 

  24. Prajapati, R., Khatri, U., Kwon, G.R.: An efficient deep neural network binary classifier for Alzheimer’s disease classification. In: International Conference on Artificial Intelligence in Information and Communication (ICAIIC), pp. 231–234, (2021)

    Google Scholar 

  25. Marcus, D.S., Fotenos, A.F., Csernansky, J.G., Morris, J.C., Buckner, R.L.: Open Access Series of Imaging Studies (OASIS): longitudinal MRI data in nondemented and demented older adults. J. Cogn. Neurosci. 22(12), 2677–2684 (2010). https://doi.org/10.1162/jocn.2009.21407

    Article  Google Scholar 

  26. Marcus, D.S., Wang, T.H., Parker, J., Csernansky, J.G., Morris, J.C., Buckner, R.L., Open Access Series of Imaging Studies (OASIS): cross-sectional MRI data in young, middle aged, nondemented, and demented older adults. J. Cogn. Neurosci., 19, 1498–1507. https://doi.org/10.1162/jocn.2007.19.9.1498

  27. Moradi, E., Pepe, A., Gaser, C., Huttunen, H., Tohka, J.: Machine learning framework for early MRI-based Alzheimer’s conversion prediction in MCI subjects. NeuroImage 104, 398–412 (2015), ISSN 1053–8119. https://doi.org/10.1016/j.neuroimage.2014.10.002

  28. Zhang, Y., Dong, Z., Phillips, P., et al.: Detection of subjects and brain regions related to Alzheimer’s disease using 3D MRI scans based on eigenbrain and machine learning. Front. Comput. Neurosci. 9, 66 (2015). https://doi.org/10.3389/fncom.2015.00066

    Article  Google Scholar 

  29. Magnin, B., Mesrob, L., Kinkingnéhun, S., et al.: Support vector machine-based classification of Alzheimer’s disease from whole-brain anatomical MRI. Neuroradiology 51, 73 (2009). https://doi.org/10.1007/s00234-008-0463-x

    Article  Google Scholar 

  30. Ma, J., Ding, Y., Cheng, J.C., Tan, Y., Gan, V.J., Zhang, J.: Analyzing the leading causes of traffic fatalities using XGBoost and grid-based analysis: a city management perspective. IEEE Access 7, 148059–148072 (2019)

    Article  Google Scholar 

  31. Filipovych, R., Davatzikos, C.: Semi-supervised pattern classification of medical images: application to mild cognitive impairment (MCI). Neuroimage 55(3), 1109–1119 (2011). https://doi.org/10.1016/j.neuroimage.2010.12.066

    Article  Google Scholar 

  32. http://scikit-learn.org/stable/modules/preprocessing.html#imputation

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Simar Preet Singh .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Shrivastava, R.K., Singh, S.P., Kaur, G. (2023). Machine Learning Models for Alzheimer’s Disease Detection Using OASIS Data. In: Koundal, D., Jain, D.K., Guo, Y., Ashour, A.S., Zaguia, A. (eds) Data Analysis for Neurodegenerative Disorders. Cognitive Technologies. Springer, Singapore. https://doi.org/10.1007/978-981-99-2154-6_6

Download citation

  • DOI: https://doi.org/10.1007/978-981-99-2154-6_6

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-99-2153-9

  • Online ISBN: 978-981-99-2154-6

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics