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Covid and Ulceration

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Uncommon Ulcers of the Extremities

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Abstract

Although the SARS-Cov-2 Corona virus primarily affects the respiratory system, causing the acute respiratory distress syndrome and pneumonia, but it can involve the other organs also including skin. COVID-19 induced illness has been coupled with various dermatologic manifestations, including rash, urticaria, retiform purpura, and vasculitis. Numerous dermal manifestations of COVID-19 occur, like lymphocytic vasculitis presenting with lesions on the toes, feet, heals, and hands occurs in COVID-19 patients. Vasculitis is a type of leukocytoclastic vasculitis with deposition of immunocomplexes. Commonly involving the children and adolescents. But none of the mechanism can explain the mechanism of ulcer formation among the COVID-19 infected patients.

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References

  1. Coronavirus resource center. https://coronavirus.jhu.edu/. Accessed 28 May 2020.

  2. Coronavirus disease (COVID-19) outbreak situation. World Health Organization. www.who.int/emergencies/diseases/novel-coronavirus-2019. Accessed 11 Apr 2020.

  3. Freeman EE, McMahon DE, Lipoff JB, et al. The spectrum of COVID-19-associated dermatologic manifestations: an international registry of 716 patients from 31 countries. J Am Acad Dermatol. 2020;83(4):1118–29.

    CAS  PubMed  PubMed Central  Google Scholar 

  4. Tang J, Li B, Gong J, Li W, Yang J. Challenges in the management of critical ill COVID -19 patients with pressure ulcer. Int Wound J. 2020;17(5):1523–4.

    PubMed  PubMed Central  Google Scholar 

  5. Li L, Li R, Wu Z, et al. Therapeutic strategies for critically ill patients with COVID-19. Ann Intensive Care. 2020;10(1):45.

    PubMed  PubMed Central  Google Scholar 

  6. Girard R, Baboi L, Ayzac L, Richard JC, Guerin C, Proseva Trial Group. The impact of patient positioning on pressure ulcers in patients with severe ARDS: results from a multicentre randomised controlled trial on prone positioning. Intensive Care Med. 2014;40(3):397–403.

    PubMed  Google Scholar 

  7. Mervis JS, Phillips TJ. Pressure ulcers: pathophysiology, epidemiology, risk factors, and presentation. J Am Acad Dermatol. 2019;81(4):881–90.

    PubMed  Google Scholar 

  8. Magro C, Mulvey JJ, Berlin D, et al. Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases. Transl Res. 2020;220:1–13.

    CAS  PubMed  PubMed Central  Google Scholar 

  9. WHO Timeline-COVID-19. https://www.who.int/news-room/detail/27-04-2020-who-timeline%2D%2D-covid-19. Accessed 28 May 2020.

  10. Coronavirus resource center. https://coronavirus.jhu.edu/map.html. Accessed 28 May 2020.

  11. Bosch-Amate X, Giavedoni P, Podlipnik S. Retiform purpura as a dermatological sign of coronavirus disease 2019 (COVID-19) coagulopathy. J Eur Acad Dermatol Venereol. 2020;34(10):e548–9.

    CAS  PubMed  PubMed Central  Google Scholar 

  12. Zhao Q, Fang X, Pang Z, Zhang B, Liu H, Zhang F. COVID-19 and cutaneous manifestations: a systematic review. J Eur Acad Dermatol Venereol. 2020;34(11):2505–10.

    CAS  PubMed  PubMed Central  Google Scholar 

  13. Martinengo L, Olsson M, Bajpai R, et al. Prevalence of chronic wounds in the general population: systematic review and meta-analysis of observational studies. Ann Epidemiol. 2019;29:8.

    PubMed  Google Scholar 

  14. Nussbaum SR, Carter MJ, Fife CE, et al. An economic evaluation of the impact, cost, and medicare policy implications of chronic nonhealing wounds. Value Health. 2018;21:27.

    PubMed  Google Scholar 

  15. Galván Casas C, Català A, Carretero Hernández G, et al. Classificationof the cutaneous manifestations of COVID-19: a rapidprospective nationwide consensus study in Spain with 375cases. Br J Dermatol. 2020;183(1):71–7. https://doi.org/10.1111/bjd.19163.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Manalo IF, Smith MK, Cheeley J, Jacobs R. A dermatologic manifestation of COVID-19: transient livedo reticularis. J Am Acad Dermatol. 2020;83(2):700. https://doi.org/10.1016/j.jaad.2020.04.018.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Zhang Y, Cao W, Xiao M, et al. Clinical and coagulation characteristicsof 7 patients with critical COVID-2019 pneumoniaand acro-ischemia. Zhonghua Xue Ye Xue Za Zhi. 2020;41:E006. https://doi.org/10.3760/cma.j.issn.0253-2727.2020.0006.

    Article  CAS  PubMed  Google Scholar 

  18. Hicks CW, Selvarajah S, Mathioudakis N, et al. Burden of infected diabetic foot ulcers on hospital admissions and costs. Ann Vasc Surg. 2016;33:149.

    PubMed  PubMed Central  Google Scholar 

  19. Llamas-Velasco M, Muñoz-Hernández P, Lázaro-González J, et al. Thrombotic occlusive vasculopathy in skin biopsy from alivedoid lesion of a COVID-19 patient. Br J Dermatol. 2020;183:591. https://doi.org/10.1111/bjd.19222.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  20. Magro C, Mulvey JJ, Berlin D, et al. Complement associatedmicrovascular injury and thrombosis in the pathogenesis ofsevere COVID-19 infection: a report of 5 cases. Transl Res. 2020;220:1–13.

    CAS  PubMed  PubMed Central  Google Scholar 

  21. Rondinelli J, Zuniga S, Kipnis P, et al. Hospital-acquired pressure injury: risk-adjusted comparisons in an integrated healthcare delivery system. Nurs Res. 2018;67(1):16–25. https://doi.org/10.1097/NNR.0000000000000258.

    Article  PubMed  PubMed Central  Google Scholar 

  22. Tang J, Li B, Gong J, Li W, Yang J. Challenges in the managementof critically ill COVID-19 patients with pressure ulcer. Int Wound J. 2020;17:1523. https://doi.org/10.1111/iwj.13399.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Connors JM, Levy JH. COVID-19 and its implications for thrombosis and anticoagulation. Blood. 2020;135(23):2033–40. https://doi.org/10.1182/blood.2020006000.

    Article  CAS  PubMed  Google Scholar 

  24. Helms J, Tacquard C, Severac F, et al. High risk of thrombosisin patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study. Intensive Care Med. 2020;46(6):1089–98. https://doi.org/10.1007/s00134-020-06062-x.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  25. Paranjpe I, Fuster V, Lala A, et al. Association of treatment dose Anticoagulation with in-hospital survival among hospitalized patients with COVID-19. J Am Coll Cardiol. 2020;76(1):122–4. https://doi.org/10.1016/j.jacc.2020.05.001. pii: S0735–1097(20)35218–9. [Epub ahead of print].

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Chaturvedi S, Braunstein EM, Yuan X, et al. Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS. Blood. 2020;135:239. https://doi.org/10.1182/blood.2019003863.

    Article  PubMed  PubMed Central  Google Scholar 

  27. Magro CM, Poe JC, Kim C, et al. Degos disease: a C5b-9/interferon-a-mediated endotheliopathy syndrome. Am J Clin Pathol. 2011;135:599–610. https://doi.org/10.1309/AJCP66QIMFARLZKI.

    Article  PubMed  Google Scholar 

  28. Ruffatti A, Calligaro A, Lacognata CS, et al. Insights into thepathogenesis of catastrophic antiphospholipid syndrome. A casereport of relapsing catastrophic antiphospholipid syndrome andreview of the literature on ischemic colitis. Clin Rheumatol. 2019;39:1347. https://doi.org/10.1007/s10067-019-04888-5.

    Article  PubMed  Google Scholar 

  29. Vaduganathan M, Vardeny O, Michel T, et al. Renin-angiotensin-aldosterone system inhibitors in patients with Covid-19. N Engl J Med. 2020;382:1653.

    CAS  PubMed  Google Scholar 

  30. Manrique-Caballero CL, Peerapornratana S, Formeck C, DelRio-Pertuz G, Gomez Danies H, Kellum JA. Typical and atypicalhemolytic uremic syndrome in the critically ill. Crit Care Clin. 2020;36:333. https://doi.org/10.1016/j.ccc.2019.11.004.

    Article  PubMed  Google Scholar 

  31. Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China. N Engl J Med. 2019;382:727. https://doi.org/10.1056/NEJMoa2001017.

    Article  Google Scholar 

  32. Cucinotta D, Vanelli M. WHO declares COVID-19 a pandemic. Acta Biomed. 2020;91(1):157–60. https://doi.org/10.23750/abm.v91i1.93973.

    Article  PubMed  PubMed Central  Google Scholar 

  33. cdc.gov/coronavirus/2019.ncov.

  34. Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 Novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020;23:1061. https://doi.org/10.1001/jama.2020.1585.

    Article  CAS  Google Scholar 

  35. Tang N, Li D, Wang X, Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost. 2020;18:844. https://doi.org/10.1111/jth.14768.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  36. World Health Organization (WHO). WHO coronavirus disease (COVID-19) dashboard. Geneva: WHO. https://covid19.who.int/.

  37. Baj J, Karakuła-Juchnowicz H, Teresiński G, et al. COVID-19: specific and non-specific clinical manifestations and symptoms: the current state of knowledge. J Clin Med. 2020;9(6):1753.

    CAS  PubMed  PubMed Central  Google Scholar 

  38. Cuker A, Peyvandi F. Coronavirus disease 2019 (COVID-19): hypercoagulability. Waltham, MA: UpToDate; 2020. https://www.uptodate.com/contents/coronavirus-disease-2019-covid-19-hypercoagulability.

    Google Scholar 

  39. Phan T. Novel coronavirus: from discovery to clinical diagnostics. Infect Genet Evol. 2020;79:104211. https://doi.org/10.1016/j.meegid.2020.104211.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  40. Gralinski LE, Sheahan TP, Morrison TE, et al. Complement activation contributes to severe acute respiratory syndrome coronavirus pathogenesis. MBio. 2018;9:e01753–18.

    PubMed  PubMed Central  Google Scholar 

  41. Xu Z, Shi L, Wang Y, et al. Pathologic findings of COVID-19associated with acute respiratory distress syndrome. Lancet Respir Med. 2020;8:420–2.

    CAS  PubMed  PubMed Central  Google Scholar 

  42. Zhang H, Zhou P, Wei Y, et al. Histopathologic changes andSARS-Cov-2 immunostaining in the lung of a patient withCOVID-19. Ann Intern Med. 2020;173:324. https://doi.org/10.7326/M20-0533.

    Article  PubMed  Google Scholar 

  43. Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395:1054–62.

    CAS  PubMed  PubMed Central  Google Scholar 

  44. Magro CM, Momtahen S, Mulvey JJ, Yassin AH, Kaplan RB, Laurence JC. The role of the skin biopsy in the diagnosis of a typical hemolytic uremic syndrome. Am J Dermatopathol. 2015;37:349–59.

    PubMed  PubMed Central  Google Scholar 

  45. Magro CM, Pope Harman A, Klinger D, et al. Use of C4d as adiagnostic adjunct in lung allograft biopsies. Am J Transplant. 2003;3:1143–54.

    CAS  PubMed  Google Scholar 

  46. Magro CM, Deng A, Pope-Harman A, et al. Humorally mediated post transplantation septal capillary injury syndrome as a commonform of pulmonary allograft rejection: a hypothesis. Transplantation. 2002;74:1273–80.

    CAS  PubMed  Google Scholar 

  47. Yao XH, Li TY, He ZC, et al. A pathological report of threeCOVID-19 cases by minimally invasive autopsies. Zhonghua Bing Li Xue Za Zhi. 2020;49(5):411–7. https://doi.org/10.3760/cma.j.cn112151-20200312-00193.

    Article  CAS  PubMed  Google Scholar 

  48. Gattinoni L, Coppola S, Cressoni M, Busana M, Chiumello D. Covid-19 does not lead to a “typical” acute respiratory distress syndrome. Am J Respir Crit Care Med. 2020;201:1299.

    CAS  PubMed  PubMed Central  Google Scholar 

  49. 10.1164/rccm.202003-0817LE.

    Google Scholar 

  50. Chen J, Wang X, Zhang S. Findings of acute pulmonary embolism in COVID-19 patients. Lanc Infect Dis. 2020.

    Google Scholar 

  51. Haq SA, Pagnoux C. Infection-associated vasculitides. Int J Rheum Dis. 2019;22:109–15.

    PubMed  Google Scholar 

  52. Teng GG, Chatham WW. Vasculitis related to viral and other microbial agents. Best Pract Res Clin Rheumatol. 2015;29:226–43.

    PubMed  Google Scholar 

  53. Jennette JC, Falk RJ, Bacon PA, et al. 2012 revised international chapel hill consensus conference nomenclature of vasculitides. Arthritis Rheum. 2013;65:1–11.

    CAS  PubMed  Google Scholar 

  54. Connors JM, Levy JH. Thromboinflammation and the hypercoagulability of COVID-19. J Thromb Haemost. 2020;18:1559–61.

    CAS  PubMed  PubMed Central  Google Scholar 

  55. Zhang Y, Xiao M, Zhang S, et al. Coagulopathy and antiphospholipid antibodies in patients with Covid-19. N Engl J Med. 2020;382:e38.

    PubMed  Google Scholar 

  56. Ackerman AB, Boer A, Bennin B, Gottlieb G. Vasculitis: basic patterns and analysis of them in histologic diagnosis of inflammatory skin diseases. In: An algorithmic method based on pattern analysis. 3rd ed. New York: Ardor Scribendi; 2005. p. 278–88.

    Google Scholar 

  57. Jennette JC, Falk RJ, Bacon PA, Basu N, Cid MC, Ferrario F, et al. Revised international chapel hill consensus conference nomenclature of vasculitides. Arthritis Rheum. 2013;65:1–11.

    CAS  PubMed  Google Scholar 

  58. Drerup C, Metze D, Ehrchen J, et al. Evidence for immunoglobulin-mediated vasculitis caused by monoclonal gammopathy in monoclonal gammopathy of unclear significance prompting oncologic treatment. JAAD Case Rep. 2019;5:288–91.

    PubMed  PubMed Central  Google Scholar 

  59. Magro C, Mulvey JJ, Berlin D, Nuovo G, Salvatore S, Harp J, et al. Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases. Transl Res. 2020;220:1–13. https://doi.org/10.1016/j.trsl.2020.04.007.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  60. Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727–33.

    CAS  PubMed  PubMed Central  Google Scholar 

  61. Hu K, Fan J, Li X, Gou X, Li X, Zhou X. The adverse skin reactions of health care workers using personal protective equipment for COVID-19. Medicine (Baltimore). 2020;99:e20603.

    CAS  PubMed  Google Scholar 

  62. Gefen A, Ousey K. Update to device-related pressure ulcers: SECURE prevention. COVID-19, face masks and skin damage. J Wound Care. 2020;29:245–59.

    PubMed  Google Scholar 

  63. Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395:1054.

    CAS  PubMed  PubMed Central  Google Scholar 

  64. Lu R, Zhao X, Li J, et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020;395:565.

    CAS  PubMed  PubMed Central  Google Scholar 

  65. Qian GQ, Yang NB, Ding F, et al. Epidemiologic and clinical characteristics of 91 hospitalized patients with COVID-19 in Zhejiang, China: a retrospective, multi-centre case series. QJM. 2020;113:474.

    CAS  PubMed  PubMed Central  Google Scholar 

  66. Bouaziz JD, Duong TA, Jachiet M, et al. Vascular skin symptoms in COVID-19: a French observational study. J Eur Acad Dermatol Venereol. 2020;34:e451.

    CAS  PubMed  PubMed Central  Google Scholar 

  67. Wollina U, Karadağ AS, Rowland-Payne C, et al. Cutaneous signs in COVID-19 patients: a review. Dermatol Ther. 2020;33:e13549.

    CAS  PubMed  PubMed Central  Google Scholar 

  68. Zhang Y, Cao W, Xiao M, et al. Clinical and coagulation characteristics of 7 patients with critical COVID-2019 pneumonia and acro-ischemia. Zhonghua Xue Ye Xue Za Zhi. 2020;41:E006.

    CAS  PubMed  Google Scholar 

  69. Tang J, Li B, Gong J, et al. Challenges in the management of critical ill COVID-19 patients with pressure ulcer. Int Wound J. 2020;17:1523.

    PubMed  PubMed Central  Google Scholar 

  70. Galvan Casas C, Catala A, Carretero Hernandez G, et al. Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases. Br J Dermatol. 2020;183(1):71–7.

    CAS  PubMed  PubMed Central  Google Scholar 

  71. Magro C, Mulvey JJ, Laurence J, et al. The differing pathophysiologiest hat underlie COVID-19 associated perniosis and thrombotic retiform purpura: a case series. Br J Dermatol. 2021;184(1):141–50.

    CAS  PubMed  PubMed Central  Google Scholar 

  72. Garrido Ruiz MC, Santos-Briz A, Santos-Briz A, et al. Spectrum of clinicopathologic findings in COVID-19-induced skin lesions: demonstration of direct viral infection of the endothelial cells. Am J Surg Pathol. 2021;45(3):293–303.

    PubMed  Google Scholar 

  73. Zhou N-Y, Yang L, Dong L-Y, et al. Prevention and treatment of skin damage caused by personal protective equipment: experience of the first-line clinicians treating 2019-nCoV infection. Int J Dermatol Venereol. [Epub ahead of print]. https://doi.org/10.1097/JD9.0000000000000085.

  74. Jiang Q, Song S, Zhou J, et al. The prevalence, characteristics, and prevention status of skin injury caused by personal protective equipment among medical staff in fighting COVID-19: a multicenter, cross-sectional study. Adv Wound Care (New Rochelle). 2020;9:357–64.

    PubMed  Google Scholar 

  75. Gefen A, Ousey K. Prevention of skin damage caused by the protective equipment used to mitigate COVID-19. J Wound Care. 2020;29:311.

    PubMed  Google Scholar 

  76. Cichowitz A, Pan WR, Ashton M. The heel: anatomy, bloodsupply, and the pathophysiology of pressure ulcers. Ann Plast Surg. 2009;62:423–9.

    CAS  PubMed  Google Scholar 

  77. Brown KL, Phillips TJ. Nutrition and wound healing. Clin Dermatol. 2010;28:432–9.

    PubMed  Google Scholar 

  78. Ma S, Yuan Z, Peng Y, Chen J, Li H, Luo Q, et al. Experience andsuggestion of medical practices for burns during the outbreakof COVID-19. Burns. 2020;46:749–55.

    PubMed  PubMed Central  Google Scholar 

  79. Hahnel E, El Genedy M, Tomova-Simitchieva T, Hauß A, Stroux A, Lechner A, et al. The effectiveness of two silicone dressingsfor sacral and heel pressure ulcer prevention comparedwith no dressings in high-risk intensive care unit patients: arandomized controlled parallel-group trial. Br J Dermatol. 2020;183:256–64.

    CAS  PubMed  Google Scholar 

  80. Apirag C, Peerasak C, Jupaporn K. Cost-effectiveness analysisin comparing alginate silver dressing with silver zinc sulfadiazinecream in the treatment of pressure ulcers. Arch Plast Surg. 2013;40:589–96.

    Google Scholar 

  81. Mataro I, Lanza A, Di Franco S, Di Franco L, Sangiuolo M, Notaro M, et al. Releasing burn-ınduced compartment syndromeby enzymatic escharotomy-debridement: a case study. J Burn Care Res. 2020;41:1097–103.

    PubMed  Google Scholar 

  82. Batra RK, Aseeja V. VAC therapy in large ınfected sacral pressureulcer grade ıv can be an alternative to flap reconstruction? Indian J Surg. 2014;76:162–4.

    CAS  PubMed  Google Scholar 

  83. Forrester JD, Nassar AK, Maggio PM, Hawn MT. Precautions for operating room team members during the COVID-19 pandemic. J Am Coll Surg. 2020;230:1098–101.

    PubMed  PubMed Central  Google Scholar 

  84. Surajit B, Mishra K. Pressure ulcers: current understanding andnewer modalities of treatment. Indian J Plast Surg. 2015;48:4–16.

    Google Scholar 

  85. Dincer M, Doger C, Tas SS, Karakaya D. An analysis of patientsin palliative care with pressure injuries. Niger J Clin Pract. 2018;21:484–91.

    CAS  PubMed  Google Scholar 

  86. Cox J, Schallom M. Pressure injuries in critical care: a survey ofcritical care nurses. Crit Care Nurse. 2017;37:46–55.

    PubMed  Google Scholar 

  87. Wall BM, Mangold T, Huch KM, Corbett C, Cooke CR. Bacteremiain the chronic spinal cord injury population: risk factors for mortality. J Spinal Cord Med. 2003;26:248–53.

    PubMed  Google Scholar 

  88. Ferrell BA, Josephson K, Norvid P, Alcorn H. Pressure ulcersamong patients admitted to home care. J Am Geriatr Soc. 2000;48:1042–7.

    CAS  PubMed  Google Scholar 

  89. Rogers LC, Armstrong DG, Capotorto J, et al. Wound center without walls: the new model of providing care during the COVID-19 pandemic. Wounds. 2020;32:178.

    PubMed  PubMed Central  Google Scholar 

  90. Prachand VN, Milner R, Angelos P, et al. Medically necessary, time-sensitive procedures: scoring system to ethically and efficiently manage resource scarcity and provider risk during the COVID-19 pandemic. J Am Coll Surg. 2020;231:281.

    PubMed  PubMed Central  Google Scholar 

  91. Zingarelli EM, Ghiglione M, Pesce M, et al. Facial pressure ulcers in a COVID-19 50-year-old female intubated patient. Indian J Plast Surg. 2020;53:144.

    PubMed  PubMed Central  Google Scholar 

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  1. Department of Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India

    Rohit Kumar Singh & Puneet Kumar

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  1. Institute of Medical Sciences, Department of Surgery, Banaras Hindu University, Varanasi, India

    Ajay K. Khanna

  2. Institute of Medical Sciences, Department of General Surgery, Banaras Hindu University, Varanasi, India

    Satyendra Kumar Tiwary

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Kumar Singh, R., Kumar, P. (2023). Covid and Ulceration. In: Khanna, A.K., Tiwary, S.K. (eds) Uncommon Ulcers of the Extremities. Springer, Singapore. https://doi.org/10.1007/978-981-99-1782-2_15

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